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Results for “Homozygous Familial Hypercholesterolemia”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Not applicableStudy completedNCT03018678
What this trial is testing

Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
University of Pennsylvania 21
Large-scale testing (Phase 3)Study completedNCT03884452
What this trial is testing

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Who this might be right for
Familial Hypercholesterolemia
Organon and Co 50
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Large-scale testing (Phase 3)Study completedNCT00943306
What this trial is testing

Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 19
Large-scale testing (Phase 3)Ended earlyNCT00263081
What this trial is testing

Efficacy of Lapaquistat Acetate Co-Administered With Current Lipid-Lowering Treatment on Blood Cholesterol Levels in Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Takeda 44
Large-scale testing (Phase 3)Study completedNCT00730236
What this trial is testing

A Safety and Efficacy Study of AEGR-733 to Treat Homozygous Familial Hypercholesterolemia (FH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Aegerion Pharmaceuticals, Inc. 29
Large-scale testing (Phase 3)Study completedNCT01624142
What this trial is testing

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders

Who this might be right for
Severe Familial Hypercholesterolemia
Amgen 300
Large-scale testing (Phase 3)Study completedNCT03409744
What this trial is testing

Evaluate the Long-Term Safety and Efficacy of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 116
Early research (Phase 1)Study completedNCT00515307
What this trial is testing

Bone Marrow Stem Cells as a Source of Allogenic Hepatocyte Transplantation in Homozygous Familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia, Familial
University of Tehran 1
Not applicableLooking for participantsNCT04370899
What this trial is testing

Early Detection of Familial Hypercholesterolemia in Children

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia - HeterozygousFamilial Hypercholesterolemia - Homozygous
Institut Investigacio Sanitaria Pere Virgili 400
Not applicableStudy completedNCT02135705
What this trial is testing

LOWER: Lomitapide Observational Worldwide Evaluation Registry

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amryt Pharma 260
Not applicableApproved For MarketingNCT06500598
What this trial is testing

Compassionate Use of Evinacumab

Who this might be right for
Pediatric Homozygous Familial Hypercholesterolemia (HoFH)Severe Hypertriglyceridemia (HTG)Dysbetalipoproteinemia (DBL)
Regeneron Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT04034485
What this trial is testing

Phase 3 Study to Evaluate the Efficacy and Safety of LIB003 With Evolocumab in HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 65
Not applicableLooking for participantsNCT07470723
What this trial is testing

The ORIGIN-FH Study

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)Homozygous Familial Hypercholesterolemia (HoFH)Familial Hypercholesterolemia
University of Wisconsin, Madison 70
Not applicableActive Not RecruitingNCT06832371
What this trial is testing

Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)Major Adverse Cardiovascular Events (MACE)Dyslipidemia
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 73
Large-scale testing (Phase 3)Study completedNCT02226198
What this trial is testing

Evaluate the Efficacy and Safety of Rosuvastatin in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca 20
Large-scale testing (Phase 3)Looking for participantsNCT05682378
What this trial is testing

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Who this might be right for
Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 195
Testing effectiveness (Phase 2)WithdrawnNCT03455777
What this trial is testing

Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akcea Therapeutics
Large-scale testing (Phase 3)Study completedNCT03399786
What this trial is testing

Efficacy and Safety of Evinacumab in Patients With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 65
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