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Results for “Human African Trypanosomiasis”

25 trials

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Showing 20 of 25 results

Large-scale testing (Phase 3)Study completedNCT03974178
What this trial is testing

Fexinidazole in Human African Trypanosomiasis Due to T. b. Rhodesiense

Who this might be right for
Trypanosomiasis, AfricanSleeping SicknessTrypanosoma Brucei Rhodesiense; Infection
Drugs for Neglected Diseases 45
Large-scale testing (Phase 3)Study completedNCT03025789
What this trial is testing

Fexinidazole in Human African Trypanosomiasis Due to T.b. Gambiense at Any Stage

Who this might be right for
Trypanosomiasis, AfricanSleeping SicknessTrypanosomiasis; Gambian
Drugs for Neglected Diseases 174
Not applicableStudy completedNCT03112655
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: Early Test-of-cure

Who this might be right for
African TrypanosomiasisAfrican; Trypanosomiasis, WestSleeping Sickness; West African+1 more
Institut de Recherche pour le Developpement 88
Large-scale testing (Phase 3)Study completedNCT01685827
What this trial is testing

Pivotal Study of Fexinidazole for Human African Trypanosomiasis in Stage 2

Who this might be right for
Human African Trypanosomiasis (HAT)Sleeping Sickness
Drugs for Neglected Diseases 394
Not applicableWithdrawnNCT05645822
What this trial is testing

Screen and Treat Implementation for HAT Control

Who this might be right for
Sleeping SicknessTrypanosomiasis, African
Institute of Tropical Medicine, Belgium
Not applicableStudy completedNCT05466630
What this trial is testing

Prospective Evaluation of the Specificity of Serological Tests for Human African Trypanosomiasis

Who this might be right for
Human African TrypanosomiasisSleeping SicknessTrypanosoma Brucei Gambiense; Infection+1 more
Institut de Recherche pour le Developpement 1,095
Large-scale testing (Phase 3)Not Yet RecruitingNCT06356974
What this trial is testing

Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)

Who this might be right for
Human African Trypanosomiasis
Drugs for Neglected Diseases 2,500
Early research (Phase 1)Study completedNCT01533961
What this trial is testing

Human African Trypanosomiasis: First in Man Clinical Trial of a New Medicinal Product, the SCYX-7158

Who this might be right for
TrypanosomiasisTrypanosomiasis, AfricanProtozoan Infections+1 more
Drugs for Neglected Diseases 136
Large-scale testing (Phase 3)Study completedNCT05256017
What this trial is testing

Safety and Tolerability Study of Acoziborole in g-HAT Seropositive Subjects

Who this might be right for
Trypanosomiasis, AfricanTrypanosoma Brucei Gambiense; InfectionSleeping Sickness
Drugs for Neglected Diseases 1,208
Large-scale testing (Phase 3)Ended earlyNCT00489658
What this trial is testing

Eflornithine + Nifurtimox Late-Stage Human African Trypanosomiasis (HAT)in West Nile, Uganda

Who this might be right for
Trypanosomiasis, African
Epicentre 31
Not applicableStudy completedNCT03356665
What this trial is testing

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection

Who this might be right for
African TrypanosomiasesWest African; TrypanosomiasisSleeping Sickness; West African+1 more
Institut de Recherche pour le Developpement 10,700
Post-approval studies (Phase 4)Study completedNCT00906880
What this trial is testing

Clinical Study to Assess the Tolerability, Feasibility and Effectiveness of Nifurtimox and Eflornithine (NECT) for the Treatment of Trypanosoma Brucei Gambiense Human African Trypanosomiasis (HAT) in the Meningo-encephalitic Phase

Who this might be right for
Human African Trypanosomiasis
Drugs for Neglected Diseases 630
Not applicableStudy completedNCT06060600
What this trial is testing

A Retrospective Analysis of Suramin Treatment for Stage 1 TBR

Who this might be right for
Trypanosoma Brucei Rhodesiense; Infection
Paxmedica 345
Large-scale testing (Phase 3)Study completedNCT00146627
What this trial is testing

Efficacy - Safety of Eflornithine-Nifurtimox Combination Versus Eflornithine to Treat Human African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 280
Large-scale testing (Phase 3)Study completedNCT03087955
What this trial is testing

Efficacy and Safety of Acoziborole (SCYX-7158) in Patients With Human African Trypanosomiasis Due to T.b. Gambiense

Who this might be right for
Trypanosomiasis, AfricanGambiense TrypanosomiasisSleeping Sickness
Drugs for Neglected Diseases 208
Early research (Phase 1)Ended earlyNCT01483170
What this trial is testing

Multiple Dose Study to Evaluate Security, Tolerance and Pharmacokinetic of Fexinidazole (Drug Candidate for Human African Trypanosomiasis) Administered With a Loading Dose and With Food

Who this might be right for
Trypanosomiasis, African
Drugs for Neglected Diseases 30
Not applicableWithdrawnNCT03394976
What this trial is testing

Prospective Evaluation of an RDT to Screen for Gambiense HAT and Diagnose P. Falciparum Malaria

Who this might be right for
Human African Trypanosomiasis
Foundation for Innovative New Diagnostics, Switzerland
Large-scale testing (Phase 3)Study completedNCT02184689
What this trial is testing

Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study

Who this might be right for
Human African Trypanosomiasis (HAT)
Drugs for Neglected Diseases 125
Large-scale testing (Phase 3)Ended earlyNCT00330148
What this trial is testing

Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis

Who this might be right for
Trypanosomiasis, African
Epicentre 435
Early research (Phase 1)Study completedNCT01340157
What this trial is testing

Fexinidazole (1200mg) Bioavailability Under Different Food Intake Conditions

Who this might be right for
PK in Healthy Volunteers
Drugs for Neglected Diseases 12
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