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Results for “Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Ended earlyNCT02540928
What this trial is testing

AMG 319 in HPV Positive and Negative HNSCC

Who this might be right for
Human Papillomavirus (HPV)Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Cancer Research UK 35
Large-scale testing (Phase 3)Active Not RecruitingNCT02215265
What this trial is testing

Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS)

Who this might be right for
Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
Lisette Nixon 1,269
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07178301
What this trial is testing

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Northwestern University 100
Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Not applicableLooking for participantsNCT06554158
What this trial is testing

De-escalation of Adjuvant Radiation for Low-Risk HPV Oropharyngeal Cancers

Who this might be right for
Oropharynx Cancer
Georgetown University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03224000
What this trial is testing

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 90
Large-scale testing (Phase 3)UnknownNCT01874171
What this trial is testing

Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Warwick 334
Not applicableLooking for participantsNCT05918510
What this trial is testing

Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus

Who this might be right for
Squamous Cell Carcinoma of the OropharynxCarcinomas of Unknown Primary SiteHigh-risk Human Papillomavirus Infection+3 more
Regina Elena Cancer Institute 142
Testing effectiveness (Phase 2)Looking for participantsNCT05491512
What this trial is testing

Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Who this might be right for
HPVThroat CancerOropharyngeal Carcinoma+2 more
Memorial Sloan Kettering Cancer Center 121
Not applicableLooking for participantsNCT05600842
What this trial is testing

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
University of California, Irvine 111
Testing effectiveness (Phase 2)Looking for participantsNCT07209189
What this trial is testing

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Who this might be right for
Head and Neck CancerSquamous Cell CarcinomaOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 75
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Testing effectiveness (Phase 2)Active Not RecruitingNCT01898494
What this trial is testing

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the OropharynxStage IVA Squamous Cell Carcinoma of the Oropharynx+1 more
ECOG-ACRIN Cancer Research Group 519
Testing effectiveness (Phase 2)UnknownNCT04920344
What this trial is testing

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+1 more
Rutgers, The State University of New Jersey
Testing effectiveness (Phase 2)Study completedNCT02159703
What this trial is testing

A Single-arm Phase II Study of Post-Transoral Robotic Surgery (TORS) Alone to the Primary Tumor Site and Selective Neck Dissection (SND) Followed by Adjuvant Radiation Therapy (+/- Chemotherapy) to the Regional Nodes for Advanced Stage, Human Papilloma Virus (HPV) Positive, Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Cancer
Abramson Cancer Center at Penn Medicine 60
Testing effectiveness (Phase 2)Looking for participantsNCT06636734
What this trial is testing

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related Neck Squamous Cell Carcinoma of Unknown PrimaryMetastatic Head and Neck Squamous Cell Carcinoma+19 more
Emory University
Testing effectiveness (Phase 2)Study completedNCT02048020
What this trial is testing

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the HypopharynxStage III Squamous Cell Carcinoma of the Larynx+13 more
Jonsson Comprehensive Cancer Center 26
Testing effectiveness (Phase 2)Study completedNCT02858310
What this trial is testing

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Who this might be right for
Papillomavirus InfectionsCervical Intraepithelial NeoplasiaCarcinoma In Situ+2 more
National Cancer Institute (NCI) 224
Not applicableLooking for participantsNCT06115772
What this trial is testing

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Who this might be right for
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Mayo Clinic 154
Testing effectiveness (Phase 2)Ended earlyNCT01221753
What this trial is testing

Docetaxel/Cisplatin/5-Fluorouracil (TPF) Human Papillomavirus (HPV) Squamous Cell Carcinoma Study

Who this might be right for
Squamous Cell Carcinoma of the Head and NeckHuman Papilloma Virus
Dana-Farber Cancer Institute 7
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