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Results for “Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer”

62 trials

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Showing 20 of 62 results

Very early researchEnded earlyNCT02827838
What this trial is testing

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

Who this might be right for
Human Papillomavirus InfectionStage I Oral Cavity Squamous Cell CarcinomaStage I Oropharyngeal Squamous Cell Carcinoma+9 more
Wake Forest University Health Sciences 17
Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Not applicableLooking for participantsNCT06902623
What this trial is testing

Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy

Who this might be right for
Oropharyngeal CancersHPVTonsil Cancer+1 more
Georgetown University 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Looking for participantsNCT07178301
What this trial is testing

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Northwestern University 100
Testing effectiveness (Phase 2)Looking for participantsNCT05307939
What this trial is testing

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

Who this might be right for
HPVOropharynx CancerHPV-Related Carcinoma+2 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06319963
What this trial is testing

Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Who this might be right for
HPV-Related Cervical CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Theravectys S.A. 72
Testing effectiveness (Phase 2)Ended earlyNCT02540928
What this trial is testing

AMG 319 in HPV Positive and Negative HNSCC

Who this might be right for
Human Papillomavirus (HPV)Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Cancer Research UK 35
Testing effectiveness (Phase 2)Ended earlyNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT05108870
What this trial is testing

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Who this might be right for
Human Papilloma VirusHPVHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Chicago 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT01898494
What this trial is testing

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the OropharynxStage IVA Squamous Cell Carcinoma of the Oropharynx+1 more
ECOG-ACRIN Cancer Research Group 519
Not applicableStudy completedNCT03226613
What this trial is testing

New Modalities for Detection of Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaOropharynx CancerBase of Tongue Carcinoma+1 more
Vanderbilt University Medical Center 51
Not applicableStudy completedNCT02147418
What this trial is testing

Exosome Testing as a Screening Modality for Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Cancer
New Mexico Cancer Research Alliance 15
Not applicableEnded earlyNCT05061940
What this trial is testing

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Who this might be right for
Head and Neck CancerMelanomaHPV-Related Malignancy+5 more
Repertoire Immune Medicines 22
Testing effectiveness (Phase 2)Active Not RecruitingNCT03224000
What this trial is testing

Trial of Magnetic Resonance Imaging Guided Radiotherapy Dose Adaptation in Human Papilloma Virus Positive Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT04920344
What this trial is testing

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+1 more
Rutgers, The State University of New Jersey
Not applicableWithdrawnNCT05849142
What this trial is testing

Feasibility of Adaptive Radiation Therapy for Human-papilloma Virus-positive Oropharyngeal Cancer Patients on MRIdian Linac

Who this might be right for
Oropharynx Cancer
University of Miami
Testing effectiveness (Phase 2)Ended earlyNCT02706691
What this trial is testing

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Who this might be right for
FGFR Gene AmplificationFGFR1 Gene AmplificationFGFR2 Gene Amplification+7 more
University of Chicago 1
Testing effectiveness (Phase 2)Study completedNCT02048020
What this trial is testing

Paclitaxel and Carboplatin Before Radiation Therapy With Paclitaxel in Treating HPV-Positive Patients With Stage III-IV Oropharynx, Hypopharynx, or Larynx Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the HypopharynxStage III Squamous Cell Carcinoma of the Larynx+13 more
Jonsson Comprehensive Cancer Center 26
Early research (Phase 1)Study completedNCT02379520
What this trial is testing

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA

Who this might be right for
Human Papillomavirus-Related CarcinomaHuman Papillomavirus Positive Oropharyngeal CarcinomaHuman Papillomavirus Positive Cervical Carcinoma+3 more
Baylor College of Medicine 32
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