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Results for “Human Papillomavirus Positive Oropharyngeal Carcinoma”

108 trials

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Showing 20 of 108 results

Very early researchEnded earlyNCT02827838
What this trial is testing

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

Who this might be right for
Human Papillomavirus InfectionStage I Oral Cavity Squamous Cell CarcinomaStage I Oropharyngeal Squamous Cell Carcinoma+9 more
Wake Forest University Health Sciences 17
Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Testing effectiveness (Phase 2)Looking for participantsNCT07497607
What this trial is testing

Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Sara Medek 31
Large-scale testing (Phase 3)Active Not RecruitingNCT04255849
What this trial is testing

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHIV-1-infectionHPV Infection
Weill Medical College of Cornell University 700
Not applicableLooking for participantsNCT06902623
What this trial is testing

Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive Radiotherapy

Who this might be right for
Oropharyngeal CancersHPVTonsil Cancer+1 more
Georgetown University 30
Not applicableStudy completedNCT06730412
What this trial is testing

CtDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPVca)

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Massachusetts Eye and Ear Infirmary 103
Testing effectiveness (Phase 2)Looking for participantsNCT07063212
What this trial is testing

Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

Who this might be right for
Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Testing effectiveness (Phase 2)Looking for participantsNCT04900623
What this trial is testing

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage+9 more
Jonathan Schoenfeld, MD, MPH 145
Testing effectiveness (Phase 2)Looking for participantsNCT07178301
What this trial is testing

Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT Trial

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Northwestern University 100
Testing effectiveness (Phase 2)Looking for participantsNCT05307939
What this trial is testing

A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)

Who this might be right for
HPVOropharynx CancerHPV-Related Carcinoma+2 more
Memorial Sloan Kettering Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06319963
What this trial is testing

Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Who this might be right for
HPV-Related Cervical CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Theravectys S.A. 72
Testing effectiveness (Phase 2)Ended earlyNCT02540928
What this trial is testing

AMG 319 in HPV Positive and Negative HNSCC

Who this might be right for
Human Papillomavirus (HPV)Positive or Negative Head and Neck Squamous Cell Carcinoma (HNSCC) of the Hypopharynx, Oropharynx, Oral Cavity, Supraglottis or Larynx
Cancer Research UK 35
Testing effectiveness (Phase 2)Ended earlyNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Large-scale testing (Phase 3)Active Not RecruitingNCT01706939
What this trial is testing

The Quarterback Trial: Reduced Dose Radiotherapy for HPV+ Oropharynx Cancer

Who this might be right for
Squamous Cell Carcinomas
Icahn School of Medicine at Mount Sinai 23
Not applicableStudy completedNCT05524025
What this trial is testing

The SPOT-HPV Study

Who this might be right for
HPV InfectionHPV Positive Oropharyngeal Squamous Cell Carcinoma
Dana-Farber Cancer Institute 360
Testing effectiveness (Phase 2)Active Not RecruitingNCT05108870
What this trial is testing

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Who this might be right for
Human Papilloma VirusHPVHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Chicago 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT04502407
What this trial is testing

Trial of De-Intensified Post-operative Chemoradiation Following Robotic Surgery for HPV-positive Oropharyngeal Cancer

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Cedars-Sinai Medical Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT01898494
What this trial is testing

Transoral Surgery Followed By Low-Dose or Standard-Dose Radiation Therapy With or Without Chemotherapy in Treating Patients With HPV Positive Stage III-IVA Oropharyngeal Cancer

Who this might be right for
Human Papilloma Virus InfectionStage III Squamous Cell Carcinoma of the OropharynxStage IVA Squamous Cell Carcinoma of the Oropharynx+1 more
ECOG-ACRIN Cancer Research Group 519
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