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Results for “Hydroxyurea Intolerance”

4 trials

Showing 4 of 4 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05329649
What this trial is testing

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)

Who this might be right for
Sickle Cell DiseaseHydroxyurea FailureHydroxyurea Intolerance+2 more
Vertex Pharmaceuticals Incorporated 13
Large-scale testing (Phase 3)Active Not RecruitingNCT04285086
What this trial is testing

Ropeginterferon Alfa-2b (P1101) vs. Anagrelide in Essential Thrombocythemia Patients With Hydroxyurea Resistance or Intolerance

Who this might be right for
Essential Thrombocythemia
PharmaEssentia 174
Post-approval studies (Phase 4)Ended earlyNCT05853458
What this trial is testing

Evaluation of HU-resistance in Adult Patients With Polycythemia Vera Who Meet PV-AIM Predictors

Who this might be right for
Polycythemia Vera
Novartis Pharmaceuticals 76
Large-scale testing (Phase 3)Active Not RecruitingNCT06079879
What this trial is testing

Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Who this might be right for
Essential Thrombocythemia
Merck Sharp & Dohme LLC 340

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