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Results for “Hyper-IgM Syndrome”

41 trials

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Showing 20 of 41 results

Early research (Phase 1)Study completedNCT00058786
What this trial is testing

Treatment of Chronic Lymphocytic B-Leukemia With IL-2 and CD-40 Autologous Tumor Cells

Who this might be right for
Chronic Lymphocytic B-Leukemia
Baylor College of Medicine 9
Early research (Phase 1)Study completedNCT00058799
What this trial is testing

Treating High Risk Leukemia With CD40 Ligand & IL-2 Gene Modified Tumor Vaccine

Who this might be right for
Leukemia
Baylor College of Medicine 11
Testing effectiveness (Phase 2)Enrolling By InvitationNCT01852370
What this trial is testing

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

Who this might be right for
Severe Combined Immunodeficiency (SCID)Immunodeficiency With Predominant T-cell Defect, UnspecifiedSevere Chronic Neutropenia+6 more
Paul Szabolcs 16
Testing effectiveness (Phase 2)Ended earlyNCT00006113
What this trial is testing

Vaccine Therapy Followed by Biological Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University of Southern California 25
Post-approval studies (Phase 4)Study completedNCT01112137
What this trial is testing

Effects of Clopidogrel on Blood Pressure

Who this might be right for
Blood PressureEndothelial FunctionPlatelet Function
University of Cologne 46
Not applicableUnknownNCT02974192
What this trial is testing

Neopterin Effects on Ischemic Stroke

Who this might be right for
Stroke
Assiut University 100
Not applicableEnded earlyNCT00266513
What this trial is testing

Studies of Disorders in Antibody Production and Related Primary Immunodeficiency States

Who this might be right for
Hyper-IgM SyndromeEctodermal Dysplasia
National Institute of Allergy and Infectious Diseases (NIAID) 119
Not applicableLooking for participantsNCT04528355
What this trial is testing

Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+2 more
Paul Szabolcs 50
Testing effectiveness (Phase 2)Study completedNCT00053391
What this trial is testing

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

Who this might be right for
Melanoma (Skin)
University Hospital Erlangen 62
Early research (Phase 1)WithdrawnNCT00224354
What this trial is testing

Lymphocytic B-Leukemia (B-CLL) w/Human IL-2 Gene Modified & Human CD40 Ligand-Expressing Autologous Tumor Cells

Who this might be right for
CHRONIC LYMPHOCYTIC B-LEUKEMIA
Baylor College of Medicine
Post-approval studies (Phase 4)Study completedNCT01289847
What this trial is testing

Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinemia+2 more
Bio Products Laboratory 25
Early research (Phase 1)Study completedNCT00078520
What this trial is testing

Treatment of B-CLL With Human IL-2 and CD40 Ligand and Plasmid Gene Modified Autologous Tumor Cells

Who this might be right for
LeukemiaLeukemia, B-Cell, Chronic
Baylor College of Medicine 9
Testing effectiveness (Phase 2)WithdrawnNCT00504322
What this trial is testing

Efficacy Study on the Transfer of Adenovirus With the CD40 Ligand Gene (AdcuCD40L) to Patients With Esophageal Carcinoma

Who this might be right for
Esophageal Neoplasms
Weill Medical College of Cornell University
Testing effectiveness (Phase 2)Study completedNCT01998633
What this trial is testing

Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)

Who this might be right for
Hemophagocytic LymphohistiocytosisChronic Active Epstein-Barr Virus InfectionChronic Granulomatous Disease+3 more
Medical College of Wisconsin 47
Testing effectiveness (Phase 2)Looking for participantsNCT01962415
What this trial is testing

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT

Who this might be right for
Primary Immunodeficiency (PID)Congenital Bone Marrow Failure SyndromesInherited Metabolic Disorders (IMD)+4 more
Paul Szabolcs 100
Large-scale testing (Phase 3)Study completedNCT00278954
What this trial is testing

Efficacy, Safety and Pharmacokinetics of Gammaplex in Primary Immunodeficiency Diseases.

Who this might be right for
Primary ImmunodeficiencyCommon Variable HypogammaglobulinemiaX-linked Hypogammaglobulinemia+3 more
Bio Products Laboratory 50
Testing effectiveness (Phase 2)Study completedNCT02320357
What this trial is testing

Pilot Study Related to the Effect of Clopidogrel on Plasmatic Soluble CD40 Ligand During Systemic Lupus Erythematous

Who this might be right for
Systemic Lupus Erythematous
University Hospital, Bordeaux 18
Testing effectiveness (Phase 2)Looking for participantsNCT06305286
What this trial is testing

Safety, Tolerability, and Efficacy of Immunomodulation With A Monoclonal Antibody Against CD40L in Combination With Transplanted Islet Cells in Adults With Brittle Type 1 Diabetes Mellitus (T1D)

Who this might be right for
Diabetes Mellitus
University of Chicago 70
Large-scale testing (Phase 3)Study completedNCT01884311
What this trial is testing

Pharmacokinetics (PK) and Safety of Subgam-VF in Primary Immunodeficiency Diseases

Who this might be right for
Primary Immune Deficiency DisordersCommon Variable ImmunodeficiencyX-linked Agammaglobulinaemia+1 more
Bio Products Laboratory 38
Not applicableStudy completedNCT05059431
What this trial is testing

The Effect of Human Prostate Tissue on Platelet Activation

Who this might be right for
Prostate HyperplasiaCoagulation; IntravascularThrombotic Disorder
Tri-Service General Hospital 8
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