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Results for “Hypercholesterolemia, Familial, 1”

15 trials

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Showing 15 of 15 results

Testing effectiveness (Phase 2)Study completedNCT01279590
What this trial is testing

Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)

Who this might be right for
MyalgiaHypercholesterolemiaHyperlipidemia
Furiex Pharmaceuticals, Inc 282
Not applicableWithdrawnNCT03756779
What this trial is testing

Cross-over Pilot Study of Blood Cholesterol Response to Dietary Saturated Fat in Patients With Autosomal Dominant Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
University of Texas Southwestern Medical Center
Large-scale testing (Phase 3)Study completedNCT04652726
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 141
Early research (Phase 1)Study completedNCT05851066
What this trial is testing

A VSA003 Phase 1 Study in Chinese Adult Healthy Volunteers

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Visirna Therapeutics HK Limited 36
Large-scale testing (Phase 3)Study completedNCT01524289
What this trial is testing

Study to Assess the Tolerability and Efficacy of Anacetrapib (MK-0859) Co-Administered With Statin in Participants With Heterozygous Familial Hypercholesterolemia (MK-0859-020)

Who this might be right for
Hyperlipoproteinemia Type IIHypercholesterolemia, Familial
Merck Sharp & Dohme LLC 306
Not applicableActive Not RecruitingNCT04656028
What this trial is testing

Genetic Testing and Motivational Counseling for FH

Who this might be right for
Hypercholesterolemia, FamilialHypercholesterolemia, Familial, 1Hypercholesterolemia, Familial, 2+23 more
National Medical Research Center for Therapy and Preventive Medicine 180
Early research (Phase 1)Study completedNCT03747224
What this trial is testing

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Who this might be right for
DyslipidemiasFamilial HypercholesterolemiaHypertriglyceridemia
Arrowhead Pharmaceuticals 93
Large-scale testing (Phase 3)Study completedNCT04659863
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 13
Not applicableLooking for participantsNCT07086989
What this trial is testing

Cardiovascular Risk in Children With Chronic Conditions Study

Who this might be right for
Kidney TransplantFamilial HypercholesterolaemiaType 1 Diabetes Mellitus (T1DM)+22 more
Semmelweis University 300
Not applicableStudy completedNCT02750527
What this trial is testing

Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany

Who this might be right for
Type 1 DiabetesFamilial Hypercholesterolemia
Kinderkrankenhaus auf der Bult 13,049
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 51
Testing effectiveness (Phase 2)Study completedNCT01604824
What this trial is testing

Alirocumab in Participants With Autosomal Dominant Hypercholesterolemia (ADH) and Gain-of-Function Mutations (GOFm) of the Proprotein Convertase Subtilisin Kexin 9 (PCSK9) Gene or Loss-of-Function Mutations (LOFm) of the Apolipoprotein (Apo) B Gene

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 23
Testing effectiveness (Phase 2)Study completedNCT05694260
What this trial is testing

A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 31
Early research (Phase 1)Study completedNCT00739999
What this trial is testing

8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Pediatric Heterozygous Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 39
Large-scale testing (Phase 3)Looking for participantsNCT06597006
What this trial is testing

Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Homozygous
Novartis Pharmaceuticals 9