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Results for “Hypercholesterolemia / Elevated LDL Cholesterol”

132 trials

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Showing 20 of 132 results

Large-scale testing (Phase 3)Study completedNCT03399370
What this trial is testing

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Who this might be right for
ASCVDElevated Cholesterol
The Medicines Company 1,561
Large-scale testing (Phase 3)Study completedNCT01516879
What this trial is testing

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study

Who this might be right for
Hypercholesterolemia
Amgen 905
Not applicableLooking for participantsNCT06833944
What this trial is testing

High Intensity Interval Training in the Treatment of Familial Hypercholesterolemia (UPPA-FH)

Who this might be right for
Familiar Hypercholesterolemia
Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental 75
Large-scale testing (Phase 3)Study completedNCT00092599
What this trial is testing

Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)

Who this might be right for
HypercholesterolemiaCoronary Disease
Organon and Co 410
Not applicableLooking for participantsNCT02009345
What this trial is testing

Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada

Who this might be right for
Familial HypercholesterolemiaLipid Disorder
McGill University Health Centre/Research Institute of the McGill University Health Centre 6,000
Large-scale testing (Phase 3)Ended earlyNCT01294683
What this trial is testing

Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118)

Who this might be right for
Primary HypercholesterolemiaDyslipidemia
Merck Sharp & Dohme LLC 977
Large-scale testing (Phase 3)Study completedNCT06005597
What this trial is testing

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHypercholesterolemiaFamilial Hypercholesterolemia+2 more
NewAmsterdam Pharma 407
Post-approval studies (Phase 4)Looking for participantsNCT06501443
What this trial is testing

LATAM LOWERS LDL-C

Who this might be right for
Hypercholesterolaemia
Novartis Pharmaceuticals 520
Early research (Phase 1)Study completedNCT05905068
What this trial is testing

Adult Subjects With Elevated Low-Density Lipoprotein-Cholesterol to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects

Who this might be right for
To Reduce the LDL-C Level in Hypercholesteremia Adult PatientsCombination for Subgroup High LDL-c Patients With Other Comorbidities
Ikaria Bioscience Pty Ltd 32
Large-scale testing (Phase 3)Study completedNCT05888103
What this trial is testing

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol.

Who this might be right for
Primary Hypercholesterolemia or Mixed Dyslipidemia
Novartis Pharmaceuticals 207
Not applicableStudy completedNCT03528031
What this trial is testing

Habitual Diet and Avocado Trial

Who this might be right for
Intra-abdominal FatMetabolic SyndromeHigh Cholesterol+11 more
Wake Forest University Health Sciences 1,008
Not applicableStudy completedNCT04494464
What this trial is testing

Treatment Rates and Compliance to Treatment in Patients With Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia
Ankara Yildirim Beyazıt University 367
Testing effectiveness (Phase 2)Study completedNCT00105066
What this trial is testing

The Effects of Metformin on Blood Vessel Structure and Function

Who this might be right for
ObesityHypertensionHypercholesterolemia+1 more
National Institute on Aging (NIA) 77
Not applicableStudy completedNCT05267522
What this trial is testing

Independent Effects of High-cholesterol (High-egg) and High-saturated Fat Diets on LDL-cholesterol

Who this might be right for
HypercholesterolemiaHyperlipidemiasPhysical Inactivity+1 more
University of South Australia 77
Large-scale testing (Phase 3)Study completedNCT00812955
What this trial is testing

Safety and Efficacy Study Comparing ABT-143 to Simvastatin in Subjects With Elevated Levels of Low Density Lipoprotein Cholesterol ("Bad Cholesterol") and Triglycerides

Who this might be right for
Dyslipidemia, Hypercholesterolemia, Hypertriglyceridemia
AstraZeneca 474
Not applicableStudy completedNCT00099684
What this trial is testing

Safety, Effectiveness, and Tolerability of Ezetimibe Combined With Statins for the Treatment of High Cholesterol in HIV Infected Adults

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 44
Post-approval studies (Phase 4)Study completedNCT07255820
What this trial is testing

Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL Cholesterol

Who this might be right for
Type 2 Diabetes MellitusHypercholesterolemia / Elevated LDL Cholesterol
Bahria University 126
Large-scale testing (Phase 3)Study completedNCT00654173
What this trial is testing

Comparing the Efficacy and Safety of Rosuvastatin With Atorvastatin and Simvastatin (SOLAR)

Who this might be right for
Hypercholesterolemia
AstraZeneca 4,444
Early research (Phase 1)Study completedNCT01163851
What this trial is testing

Pharmacokinetic And Pharmacodynamic Study Of A Single-Dose Of PF-04950615 (RN316) In Combination With Atorvastatin

Who this might be right for
HypercholesterolemiaDyslipidemia
Pfizer 25
Large-scale testing (Phase 3)Study completedNCT00092625
What this trial is testing

Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)

Who this might be right for
HypercholesterolemiaCoronary Disease
Organon and Co 442
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