Large-scale testing (Phase 3)Study completedNCT04724629What this trial is testingSurvival TRial Using CytoKines in COVID-19 (STRUCK Trial)Who this might be right forCovid19 University of Sao Paulo 60
Not applicableStudy completedNCT04226430What this trial is testingEffect of Cytosorb on Blood Levels of Inflammatory Biomarkers of Sepsis.Who this might be right forSepsisCytokine Storm University of Gaziantep 34
Large-scale testing (Phase 3)Ended earlyNCT04403685What this trial is testingSafety and Efficacy of Tocilizumab in Moderate to Severe COVID-19 With Inflammatory MarkersWho this might be right forCOVIDSARS PneumoniaCytokine Release Syndrome Beneficência Portuguesa de São Paulo 129
Large-scale testing (Phase 3)Study completedNCT04979884What this trial is testingSafety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University HospitalWho this might be right forCOVID-19 Acute Respiratory Distress SyndromeCytokine Release SyndromePulmonary Fibrosis Alexandria University 66
Not applicableStudy completedNCT04873141What this trial is testingTocilizumab and Cytokine Release Syndrome (CRS) In Covid-19 PneumoniaWho this might be right forCytokine Release SyndromeCovid-19 Pneumonia Shaheed Zulfiqar Ali Bhutto Medical University 24
Not applicableStudy completedNCT04901338What this trial is testingCytokine Hemoadsorption in ECMO PatientsWho this might be right forSIRSCytokine StormCardiogenic Shock+3 more University Medical Centre Ljubljana 25
Not applicableStudy completedNCT04761913What this trial is testingPaediatric Inflammatory Multisystem Syndrome During COVID-19 PandemicWho this might be right forPaediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-Cov-2 Anglia Ruskin University 40
Large-scale testing (Phase 3)UnknownNCT04433949What this trial is testingBest Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19Who this might be right forPneumoniaSevere Acute Respiratory SyndromeSymptomatic COVID-19 Infection Laboratory-Confirmed Emory University 14
Testing effectiveness (Phase 2)Looking for participantsNCT05972135What this trial is testingOutpatient Administration of Teclistamab or Talquetamab for Multiple MyelomaWho this might be right forMultiple Myeloma SCRI Development Innovations, LLC 100
Not applicableStudy completedNCT05510596What this trial is testingMagnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity SyndromeWho this might be right forLymphoma, B-CellNeurotoxicity University Hospital, Montpellier 25
Early research (Phase 1)Looking for participantsNCT06008808What this trial is testingRuxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell TransplantationWho this might be right forGraft Vs Host DiseaseGraft-versus-host-diseaseGraft Versus Host Disease Washington University School of Medicine 41
Large-scale testing (Phase 3)Not Yet RecruitingNCT07497438What this trial is testingComparison of Two Etoposide Initiation Strategies for Severe Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic Lymphohistiocytosis Assistance Publique - Hôpitaux de Paris 176
Testing effectiveness (Phase 2)Ended earlyNCT04482699What this trial is testingRAPA-501-Allo Therapy of COVID-19-ARDSWho this might be right forSevere COVID-19 Disease Rapa Therapeutics LLC 1
Not applicableNo Longer AvailableNCT04355793What this trial is testingExpanded Access Program of Ruxolitinib for the Emergency Treatment of Cytokine Storm From COVID-19 InfectionWho this might be right forCOVID-19 Incyte Corporation
Not applicableLooking for participantsNCT05191381What this trial is testingImmune Modulation by Exosomes in COVID-19Who this might be right forCOVID-19Critical IllnessHypercytokinemia+1 more University of Ulm 40
Large-scale testing (Phase 3)Ended earlyNCT04371393What this trial is testingMSCs in COVID-19 ARDSWho this might be right forMesenchymal Stromal CellsRemestemcel-LAcute Respiratory Distress Syndrome+1 more Icahn School of Medicine at Mount Sinai 223
Not applicableStudy completedNCT04910893What this trial is testingCytokine Adsorption in Severe, Refractory Septic ShockWho this might be right forSeptic ShockCytokine Storm University of Zurich 48
Not applicableUnknownNCT04332913What this trial is testingEfficacy and Safety of Tocilizumab in the Treatment of SARS-Cov-2 Related PneumoniaWho this might be right forCOVID-19 Pneumonia University of L'Aquila 30
Post-approval studies (Phase 4)UnknownNCT05491304What this trial is testingCytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic LymphohistiocytosisWho this might be right forHemophagocytic LymphohistiocytosesCytokine Storm The Children's Hospital of Zhejiang University School of Medicine 400
Not applicableUnknownNCT05058742What this trial is testingNon-invasive Nervus Vagus Stimulation in Patients With COVID-19 and ARDSWho this might be right forCOVID-19ARDSCytokine Storm Vienna Hospital Association 20