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Results for “Hyperhomocysteinemia”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Temporarily pausedNCT04015557
What this trial is testing

Effect of Acetaminophen and N-Acetylcysteine on Liver Metabolism on Homocystinuria

Who this might be right for
CBS Deficiency
Hospital de Clinicas de Porto Alegre 10
Not applicableLooking for participantsNCT06556615
What this trial is testing

Health Related Quality of Life (HrQoL) in Classical Homocystinuria (CBS Deficiency)

Who this might be right for
Homocystinuria
University Children's Hospital, Zurich 80
Large-scale testing (Phase 3)Enrolling By InvitationNCT06431893
What this trial is testing

A Long-term Extension Study to Assess the Long-term Safety and Efficacy of Pegtibatinase Treatment in Participants ≥5 to ≤65 Years of Age With Classical Homocystinuria (HCU) (ENSEMBLE)

Who this might be right for
Homocystinuria
Travere Therapeutics, Inc. 100
Not applicableStudy completedNCT00626223
What this trial is testing

5-methyltetrahydrofolate Survival and Inflammation in ESRD Patients

Who this might be right for
MortalityHyperhomocysteinemiaInflammation
IRCCS Azienda Ospedaliero-Universitaria di Bologna 341
Testing effectiveness (Phase 2)Looking for participantsNCT03406611
What this trial is testing

Pegtibatinase as a Treatment for Patients With Classical Homocystinuria (HCU) (Also Known as the COMPOSE Study)

Who this might be right for
Homocystinuria
Travere Therapeutics, Inc. 39
Not applicableUnknownNCT06622577
What this trial is testing

The Effect of Dietary Management and Cysteine Supplementation on Growth Parameters and Biochemical Control for Pediatric Qatari Patients Affected with Classical B6 Non-responsive Homocystinuria.

Who this might be right for
Classical Homocystinuria
Hamad Medical Corporation 50
Testing effectiveness (Phase 2)Ended earlyNCT05154890
What this trial is testing

A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency

Who this might be right for
Homocystinuria Due to Cystathionine Beta-Synthase Deficiency
Aeglea Biotherapeutics 13
Not applicableStudy completedNCT02998710
What this trial is testing

Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

Who this might be right for
Homocystinuria Due to CBS Deficiency
Travere Therapeutics, Inc. 110
Not applicableStudy completedNCT02392767
What this trial is testing

Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function

Who this might be right for
Endothelial DysfunctionHyperhomocysteinemiaHypertension Grade I, Subgroup "Borderline" (WHO)
Dr. Loges & Co. GmbH 25
Testing effectiveness (Phase 2)Study completedNCT02404337
What this trial is testing

Betaine METABOLISM OF PATIENTS With Homocystinuria

Who this might be right for
Homocystinuria
Assistance Publique - Hôpitaux de Paris 12
Early research (Phase 1)Study completedNCT05462132
What this trial is testing

Safety, Tolerability and Pharmacodynamics of SYNB1353 in Healthy Adult Volunteers

Who this might be right for
Homocystinuria
Synlogic 31
Not applicableLooking for participantsNCT00078078
What this trial is testing

Clinical and Laboratory Study of Methylmalonic Acidemia

Who this might be right for
Organic AcidemiaMethylmalonic AcidemiaInborn Errors of Metabolism
National Human Genome Research Institute (NHGRI) 2,275
Not applicableStudy completedNCT01391416
What this trial is testing

Prevalence Of Hyperhomocysteinemia In Thai Chronic Kidney Disease (CKD) Patients

Who this might be right for
Cardiovascular DiseaseHyperhomocysteinemia
Bangkok Metropolitan Administration Medical College and Vajira Hospital 98
Not applicableUnknownNCT04935970
What this trial is testing

Metabolic Disorders and Vertigo

Who this might be right for
Benign Paroxysmal Positional Vertigo (BPPV)Vestibular MigraineCentral Positional Vertigo+2 more
I.M. Sechenov First Moscow State Medical University 100
Post-approval studies (Phase 4)Study completedNCT00317005
What this trial is testing

Uremic Hyperhomocysteinemia -A Folate Trial for Possible Prevention of Cardiovascular Events

Who this might be right for
UremiaChronic Renal FailureHemodialysis+2 more
Universidade Estadual de Londrina 186
Not applicableStudy completedNCT06163443
What this trial is testing

Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.

Who this might be right for
HyperhomocysteinemiaHyperlipoproteinemias
S.LAB (SOLOWAYS) 54
Large-scale testing (Phase 3)Study completedNCT00755664
What this trial is testing

Effects of Low-dose Complex B-vitamins on Homocysteine and Framingham Risk Score Among Chinese Elderly

Who this might be right for
Hyperhomocysteinemia
Peking University 390
Not applicableLooking for participantsNCT07480265
What this trial is testing

Homocysteine and Early Diastolic Dysfunction in Newly Diagnosed Hypertension

Who this might be right for
Hypertension (HTN)HyperhomocysteinemiaDiastolic Dysfunction
Necmettin Erbakan University 500
Not applicableStudy completedNCT00004495
What this trial is testing

Randomized Study of Folic Acid Therapy for Hyperhomocysteinemia in Patients With End Stage Renal Disease Receiving Hemodialysis

Who this might be right for
End Stage Renal DiseaseHyperhomocysteinemia
Georgetown University 84
Not applicableStudy completedNCT01661309
What this trial is testing

Supplementary Vitamin B12 Effects on Elevated Homocysteine Levels of Vegetarians - Clinical Trial

Who this might be right for
Vitamin B12 Deficiency
University of West London 50
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