Not applicableStudy completedNCT02722863What this trial is testingSamsca Post Marketing Surveillance StudyWho this might be right forHypervolemic and Euvolemic Hyponatremia Korea Otsuka Pharmaceutical Co., Ltd. 908
Post-approval studies (Phase 4)Study completedNCT04447911What this trial is testingEffects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic HyponatremiaWho this might be right forHyponatremiaSIADHLiver Failure+1 more University Hospital, Basel, Switzerland 113
Large-scale testing (Phase 3)WithdrawnNCT02442674What this trial is testingA Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic HyponatremiaWho this might be right forHyponatremia Otsuka Pharmaceutical Development & Commercialization, Inc.
Large-scale testing (Phase 3)Ended earlyNCT02012959What this trial is testingStudy of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Otsuka Pharmaceutical Development & Commercialization, Inc. 9
Large-scale testing (Phase 3)Ended earlyNCT00843986What this trial is testingSafety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)Who this might be right forHyponatremiaAcute Decompensated Heart Failure Cumberland Pharmaceuticals 9
Large-scale testing (Phase 3)Ended earlyNCT01451411What this trial is testingAssess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Cumberland Pharmaceuticals 4
Large-scale testing (Phase 3)Study completedNCT00492037What this trial is testingStudy of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Cumberland Pharmaceuticals 83
Large-scale testing (Phase 3)Ended earlyNCT01227512What this trial is testingEffects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional HyponatremiaWho this might be right forHyponatremiaDilutional HyponatremiaInappropriate ADH Syndrome Otsuka Pharmaceutical Development & Commercialization, Inc. 124
Large-scale testing (Phase 3)Study completedNCT00478192What this trial is testingStudy of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Cumberland Pharmaceuticals 50
Not applicableStudy completedNCT01240668What this trial is testingHyponatremia Registry for Patients With Euvolemic and Hypervolemic HyponatremiaWho this might be right forEuvolemic HyponatremiaHypervolemic Hyponatremia Otsuka America Pharmaceutical 5,028
Large-scale testing (Phase 3)Study completedNCT00379847What this trial is testingAn Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Cumberland Pharmaceuticals 251
Post-approval studies (Phase 4)Ended earlyNCT01890694What this trial is testingTolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and HyponatremiaWho this might be right forHyponatremia NYU Langone Health 2
Large-scale testing (Phase 3)WithdrawnNCT00684164What this trial is testingSafety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological PatientsWho this might be right forHyponatremia Columbia University
Not applicableStudy completedNCT01056848What this trial is testingInternational, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430Who this might be right forHyponatremia With Normal Extracellular Fluid VolumeHyponatremia With Excess Extracellular Fluid Volume CardioKine Inc. 135
Post-approval studies (Phase 4)Study completedNCT00435591What this trial is testingMultiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremiaEuvolemiaHypervolemia Cumberland Pharmaceuticals 121
Large-scale testing (Phase 3)Study completedNCT00380575What this trial is testingStudy of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Cumberland Pharmaceuticals 84
Large-scale testing (Phase 3)Ended earlyNCT02020278What this trial is testingAn Extension Follow-up Trial to Evaluate the Long-term Safety of Children and Adolescent Participants With Euvolemic or Hypervolemic HyponatremiaWho this might be right forHyponatremia Otsuka Pharmaceutical Development & Commercialization, Inc. 3