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Results for “Hypophosphatasia”

47 trials

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Showing 20 of 47 results

Post-approval studies (Phase 4)WithdrawnNCT06015750
What this trial is testing

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableStudy completedNCT02235493
What this trial is testing

Non-interventional Substudy of ALX-HPP-502 to Assess Natural History of Patients With Juvenile-onset HPP Who Served as Historical Controls in ENB-006-09

Who this might be right for
HypophosphatasiaBone Disease
Alexion Pharmaceuticals, Inc. 6
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableUnknownNCT04181164
What this trial is testing

Evaluation of Bone Architecture and Bone Strength in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Hvidovre University Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01163149
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 19
Large-scale testing (Phase 3)Active Not RecruitingNCT06079281
What this trial is testing

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 124
Not applicableStudy completedNCT02796885
What this trial is testing

Characterisation of Adult-Onset Hypophosphatasia

Who this might be right for
Hypophosphatasia
Sheffield Teaching Hospitals NHS Foundation Trust 60
Large-scale testing (Phase 3)Study completedNCT01176266
What this trial is testing

Open-Label Study of Asfotase Alfa in Infants and Children ≤ 5 Years of Age With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 69
Not applicableApproved For MarketingNCT02496689
What this trial is testing

Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableUnknownNCT06161142
What this trial is testing

Characteristics of Hypophosphatasia in Adult Patients in Rheumatology

Who this might be right for
Hypophosphatasia
University of Bonn 60
Testing effectiveness (Phase 2)Study completedNCT02456038
What this trial is testing

Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 13
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Not applicableStudy completedNCT02104219
What this trial is testing

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 32
Not applicableStudy completedNCT05062629
What this trial is testing

United States Hypophosphatasia Molecular Research Center

Who this might be right for
Hypophosphatasia
Children's Mercy Hospital Kansas City 29
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Not applicableLooking for participantsNCT07390240
What this trial is testing

The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia

Who this might be right for
Hypophosphatasia
AstraZeneca 55
Large-scale testing (Phase 3)Active Not RecruitingNCT06079359
What this trial is testing

Phase 3 Study of ALXN1850 in Treatment-Naïve Pediatric Participants With HPP

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 30
Not applicableLooking for participantsNCT05596539
What this trial is testing

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

Who this might be right for
Hypophosphatasia
Assistance Publique - Hôpitaux de Paris 200
Post-approval studies (Phase 4)Study completedNCT02531867
What this trial is testing

Post-approval Clinical Study of Asfotase Alfa Treatment for Patients With Hypophosphatasia (HPP) in Japan

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 13
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