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Results for “Hypophosphatasia”

46 trials

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Showing 20 of 46 results

Post-approval studies (Phase 4)WithdrawnNCT04189315
What this trial is testing

Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableWithdrawnNCT02603042
What this trial is testing

Biomarker for Hypophosphatasia Disease (BioHypophos)

Who this might be right for
Defective Mineralization
CENTOGENE GmbH Rostock
Not applicableLooking for participantsNCT05062629
What this trial is testing

United States Hypophosphatasia Molecular Research Center

Who this might be right for
Hypophosphatasia
Children's Mercy Hospital Kansas City 66
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Post-approval studies (Phase 4)WithdrawnNCT06015750
What this trial is testing

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableStudy completedNCT02751801
What this trial is testing

Health Burden of Hypophosphatasia

Who this might be right for
Hypophosphatasia
Sheffield Teaching Hospitals NHS Foundation Trust 28
Not applicableStudy completedNCT06689709
What this trial is testing

Serum Alkaline Phosphatase Levels In Healthy Turkish Children

Who this might be right for
Alkaline Phosphatase DeficiencyVitamin D Deficiency
Emine Hafize 1,000
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Looking for participantsNCT07179640
What this trial is testing

Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1

Who this might be right for
Hypophosphatasia (HPP)
Alesta Therapeutics 120
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Testing effectiveness (Phase 2)Study completedNCT01163149
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Adolescents and Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 19
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Study completedNCT02797821
What this trial is testing

Pharmacokinetic and Dose Response Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 27
Early research (Phase 1)Study completedNCT00739505
What this trial is testing

Safety Study of Human Recombinant Tissue Non-Specific Alkaline Phosphatase Fusion Protein Asfotase Alfa in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 6
Not applicableUnknownNCT04222452
What this trial is testing

The PORTRAIT Study

Who this might be right for
Hypophosphatasia
Sheffield Teaching Hospitals NHS Foundation Trust 14
Not applicableLooking for participantsNCT05596539
What this trial is testing

Prospective, Longitudinal, Observational Registry of Adult Patients With Hypophosphatasia (REG-HYPO)

Who this might be right for
Hypophosphatasia
Assistance Publique - Hôpitaux de Paris 130
Testing effectiveness (Phase 2)Study completedNCT00744042
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 11
Not applicableLooking for participantsNCT05234567
What this trial is testing

A Prospective Sub-Study of the Global Hypophosphatasia Registry

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 30
Not applicableUnknownNCT04018287
What this trial is testing

Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia

Who this might be right for
HypophosphatasiaBone Diseases, MetabolicBone
Medical University of Vienna 60
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