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Results for “Hypophosphatasia”

47 trials

Showing 20 of 47 results

Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableStudy completedNCT02104219
What this trial is testing

Retrospective, Non-interventional Natural History of Patients With Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 32
Not applicableLooking for participantsNCT07390240
What this trial is testing

The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia

Who this might be right for
Hypophosphatasia
AstraZeneca 55
Not applicableStudy completedNCT01419028
What this trial is testing

A Retrospective Study of the Natural History of Patients With Severe Perinatal and Infantile Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 48
Not applicableStudy completedNCT03418389
What this trial is testing

Evaluate and Monitor Physical Performance of Adults Treated With Asfotase Alfa for Hypophosphatasia

Who this might be right for
Hypophosphatasia
Dr. Lothar Seefried 23
Not applicableStudy completedNCT04195763
What this trial is testing

Patient Reported Outcomes in Adults With Pediatric-onset Hypophosphatasia Treated With Strensiq® (Asfotase Alfa)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT00952484
What this trial is testing

Safety and Efficacy of Asfotase Alfa in Juvenile Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT01205152
What this trial is testing

Extension Study of Protocol ENB-002-08 - Study of Asfotase Alfa in Infants and Young Children With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc. 10
Testing effectiveness (Phase 2)Study completedNCT02456038
What this trial is testing

Safety and Efficacy of Asfotase Alfa in Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 13
Not applicableWithdrawnNCT02603042
What this trial is testing

Biomarker for Hypophosphatasia Disease (BioHypophos)

Who this might be right for
Defective Mineralization
CENTOGENE GmbH Rostock
Not applicableNot Yet RecruitingNCT07594639
What this trial is testing

GRACE II (General Retrospective Analysis of Commercial Experience With AGN1 LOEP)

Who this might be right for
Osteoporosis
AgNovos Healthcare, LLC 305
Testing effectiveness (Phase 2)WithdrawnNCT00894075
What this trial is testing

Safety and Efficacy Study of ENB-0040 in Juvenile Patients With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableUnknownNCT04018287
What this trial is testing

Circulating miRNAs and Bone Microstructure in Adults With Hypophosphatasia

Who this might be right for
HypophosphatasiaBone Diseases, MetabolicBone
Medical University of Vienna 60
Not applicableApproved For MarketingNCT02496689
What this trial is testing

Expanded Access Program for Asfotase Alfa Treatment for Patients With Infantile- or Juvenile-onset Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Alexion Pharmaceuticals, Inc.
Not applicableStudy completedNCT02751801
What this trial is testing

Health Burden of Hypophosphatasia

Who this might be right for
Hypophosphatasia
Sheffield Teaching Hospitals NHS Foundation Trust 28
Testing effectiveness (Phase 2)Looking for participantsNCT07179640
What this trial is testing

Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ALE1 in Healthy Adults and Adults With Hypophosphatasia in Order to Identify Suitable Doses of ALE1

Who this might be right for
Hypophosphatasia (HPP)
Alesta Therapeutics 120
Not applicableEnrolling By InvitationNCT02306720
What this trial is testing

Registry of Patients With Hypophosphatasia

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 1,571
Not applicableStudy completedNCT02291497
What this trial is testing

Burden of Disease in Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Wuerzburg University Hospital 114
Testing effectiveness (Phase 2)Study completedNCT00744042
What this trial is testing

Safety and Efficacy Study of Asfotase Alfa in Severely Affected Infants With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia (HPP)
Alexion Pharmaceuticals, Inc. 11
Testing effectiveness (Phase 2)Study completedNCT01406977
What this trial is testing

Dose Escalation Study to Evaluate the Safety and Tolerability of Multiple Infusions of BPS804 in Adults With Hypophosphatasia (HPP)

Who this might be right for
Hypophosphatasia
Ultragenyx Pharmaceutical Inc 8
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