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Results for “Hypoxia Inducible Factor (HIF)”

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Showing 20 of 0 results

Large-scale testing (Phase 3)WithdrawnNCT03242967
What this trial is testing

Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)

Who this might be right for
AnemiaDialysis-Dependent Chronic Kidney Disease
Akebia Therapeutics
Large-scale testing (Phase 3)Active Not RecruitingNCT05239728
What this trial is testing

Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 1,800
Large-scale testing (Phase 3)WithdrawnNCT05082571
What this trial is testing

Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease

Who this might be right for
Anemia of Chronic Kidney Disease
Akebia Therapeutics
Early research (Phase 1)Study completedNCT05117554
What this trial is testing

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers

Who this might be right for
Healthy Participants
Arcus Biosciences, Inc. 70
Testing effectiveness (Phase 2)Study completedNCT03054350
What this trial is testing

Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Dialysis-Dependent Chronic Kidney Disease (DD-CKD)

Who this might be right for
AnemiaDialysis Dependent Chronic Kidney Disease
Akebia Therapeutics 60
Testing effectiveness (Phase 2)Ended earlyNCT05935748
What this trial is testing

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Who this might be right for
ccRCCClear Cell Renal Cell CarcinomaKidney Cancer+18 more
NiKang Therapeutics, Inc. 18
Early research (Phase 1)Study completedNCT02564614
What this trial is testing

Hypoxia-inducible Factor 1a (HIF1A) Messenger Ribonucleic Acid (mRNA) Antagonist (RO7070179), to Demonstrate Proof-of-mechanism in Adult Participants With Hepatocellular Carcinoma (HCC)

Who this might be right for
Carcinoma, Hepatocellular
Hoffmann-La Roche 9
Early research (Phase 1)Study completedNCT03639155
What this trial is testing

A Study in Evaluating Bioequivalence Between Test and Reference Formulations of Vadadustat Tablets in Healthy Adults

Who this might be right for
Healthy
Akebia Therapeutics 50
Testing effectiveness (Phase 2)Ended earlyNCT05119335
What this trial is testing

NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Who this might be right for
ccRCCClear Cell Renal Cell CarcinomaKidney Cancer+14 more
NiKang Therapeutics, Inc. 120
Testing effectiveness (Phase 2)WithdrawnNCT00960921
What this trial is testing

Study of the Effects of Iron on Lung Blood Pressure at High Altitude

Who this might be right for
Hypertension, Pulmonary
University of Oxford
Not applicableStudy completedNCT07025291
What this trial is testing

Assessment of Salivary Biomarker Levels in Individuals With Various Periodontal Diseases

Who this might be right for
Periodontal Diseases
Izmir Katip Celebi University 60
Large-scale testing (Phase 3)Study completedNCT02680574
What this trial is testing

Efficacy and Safety Study to Evaluate Vadadustat for the Maintenance Treatment of Anemia in Participants With Non-dialysis-dependent Chronic Kidney Disease (NDD-CKD)

Who this might be right for
AnemiaNon-Dialysis-Dependent Chronic Kidney Disease
Akebia Therapeutics 1,725
Early research (Phase 1)Active Not RecruitingNCT05030506
What this trial is testing

Belzutifan (MK-6482) as Monotherapy and in Combination With Lenvatinib (E7080/MK-7902) With or Without Pembrolizumab (MK-3475) in China Participants With Advanced Renal Cell Carcinoma (MK-6482-010)

Who this might be right for
Renal Cell Carcinoma
Merck Sharp & Dohme LLC 45
Post-approval studies (Phase 4)Study completedNCT00880672
What this trial is testing

Effect of Dutasteride on HIF-1alpha and VEGF in the Prostate

Who this might be right for
Benign Prostatic Hyperplasia
Seoul National University Hospital 40
Testing effectiveness (Phase 2)Study completedNCT03054337
What this trial is testing

Dose-Finding Study of Vadadustat in Japanese Subjects With Anemia Secondary to Non-Dialysis Dependent Chronic Kidney Disease (NDD-CKD)

Who this might be right for
AnemiaNon-dialysis Dependent Chronic Kidney Disease
Akebia Therapeutics 51
Not applicableStudy completedNCT00952302
What this trial is testing

Study of the Effects of Iron Levels on the Lungs at High Altitude

Who this might be right for
Pulmonary HypertensionMountain Sickness
University of Oxford 33
Not applicableStudy completedNCT06942650
What this trial is testing

The Effect of Prolonged ischemıa and anesthetıc Agents on Oxidative Stress

Who this might be right for
Tourniquet PainIschemia-reperfusionPostoperative Pain+2 more
Duzce University 60
Not applicableStudy completedNCT01600989
What this trial is testing

Mitochondrial Function of Immune Cells in Sepsis

Who this might be right for
Shock, Septic
Insel Gruppe AG, University Hospital Bern 60
Large-scale testing (Phase 3)Active Not RecruitingNCT04195750
What this trial is testing

Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 755
Not applicableUnknownNCT00154973
What this trial is testing

Expression of Hypoxia-Inducible Factor-α in Oral Precancers and Cancers

Who this might be right for
Oral Cancer
National Taiwan University Hospital 60
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