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Results for “IDH Mutation”

58 trials

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Showing 20 of 58 results

Testing effectiveness (Phase 2)Looking for participantsNCT05345002
What this trial is testing

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Who this might be right for
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCE 55
Not applicableUnknownNCT06481345
What this trial is testing

Characterization of Myeloproliferative Neoplasia With a Mutated IDH, SRSF2 or SF3B1 Allele (CARPEDIEM)

Who this might be right for
Myeloproliferative Disorders
University Hospital, Brest 300
Not applicableUnknownNCT05595863
What this trial is testing

Correlation Between SPECT/CT and IDH Mutation in Brain Glioma

Who this might be right for
Brain Glioma
Assiut University 40
Not applicableStudy completedNCT04304300
What this trial is testing

Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes

Who this might be right for
Astrocytoma, Grade IIAstrocytoma, Grade IIIOligodendroglioma+1 more
Erasmus Medical Center 80
Not applicableStudy completedNCT06620926
What this trial is testing

Impact of IDH Mutation and Adjuvant Chemo(radio)therapy on Survival Outcome in Grade II/III Astrocytoma

Who this might be right for
AstrocytomaAstrocytic TumorsAstrocytoma of Brain
asmaa salama ibrahim 811
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Very early researchLooking for participantsNCT06636162
What this trial is testing

Window of Opportunity Study of DSP-0390 in Gliomas

Who this might be right for
Glioma, MalignantIDH Mutation
Washington University School of Medicine 20
Early research (Phase 1)Looking for participantsNCT02074839
What this trial is testing

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia (AML)Untreated AMLOther IDH1-mutated Positive Hematologic Malignancies+1 more
Institut de Recherches Internationales Servier 291
Early research (Phase 1)Active Not RecruitingNCT02632708
What this trial is testing

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia (AML)Untreated AMLAML Arising From Myelodysplastic Syndrome (MDS)+2 more
Institut de Recherches Internationales Servier 153
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Not applicableLooking for participantsNCT05190172
What this trial is testing

PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas

Who this might be right for
OligodendrogliomaOligodendroglioma, AnaplasticDiffuse Astrocytoma, IDH-Mutant
Oslo University Hospital 225
Testing effectiveness (Phase 2)UnknownNCT02209428
What this trial is testing

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

Who this might be right for
AstrocytomaOligodendrogliomaOligoastrocytoma
Huashan Hospital 54
Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Not applicableNot Yet RecruitingNCT07439302
What this trial is testing

Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma

Who this might be right for
OncologyGlioma
Assistance Publique - Hôpitaux de Paris 80
Not applicableUnknownNCT04369287
What this trial is testing

Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIDH2 Gene Mutation
Istituto Clinico Humanitas 654
Not applicableNot Yet RecruitingNCT07469735
What this trial is testing

Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma

Who this might be right for
GliomaDiffuse GliomaRecurrent Gliomas
Huashan Hospital 10
Early research (Phase 1)Not Yet RecruitingNCT07629089
What this trial is testing

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

Who this might be right for
Brain Cancer
Megan Mantica 24
Early research (Phase 1)Active Not RecruitingNCT04603001
What this trial is testing

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+1 more
Eli Lilly and Company 260
Early research (Phase 1)Active Not RecruitingNCT03528642
What this trial is testing

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Astrocytoma, IDH-Mutant, Grade 3
National Cancer Institute (NCI) 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06478212
What this trial is testing

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

Who this might be right for
IDH1-mutant GliomaIDH2-mutant Glioma
Institut de Recherches Internationales Servier 51
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