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Results for “IDH Mutation”

61 trials

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Showing 20 of 61 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06780930
What this trial is testing

Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation

Who this might be right for
Residual or Recurrent Grade 2 IDH Mutant Glioma
Servier 57
Testing effectiveness (Phase 2)Looking for participantsNCT05401097
What this trial is testing

IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)

Who this might be right for
Acute Myeloid Leukemia
Alice Mims 125
Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Early research (Phase 1)Ended earlyNCT04764474
What this trial is testing

HMPL-306 in Advanced Hematological Malignancies With mIDH

Who this might be right for
Isocitrate Dehydrogenase Gene Mutation
Hutchmed 46
Testing effectiveness (Phase 2)Study completedNCT02273739
What this trial is testing

Study of Orally Administered Enasidenib (AG-221) in Adults With Advanced Solid Tumors, Including Glioma, or Angioimmunoblastic T-cell Lymphoma, With an IDH2 Mutation

Who this might be right for
Solid TumorGliomaAngioimmunoblastic T-cell Lymphoma+2 more
Celgene 21
Not applicableNot Yet RecruitingNCT07710131
What this trial is testing

Neurocognitive Assessment CNSL and LGG

Who this might be right for
PCNSLBrain TumorCognitive Dysfunction+2 more
Dana-Farber Cancer Institute 36
Not applicableUnknownNCT04908267
What this trial is testing

How the Precise Habitats Can Predict the IDH Mutation Status and Prognosis of the Patients With High-grade Gliomas

Who this might be right for
High-grade Glioma
Weiguo Zhang 100
Not applicableLooking for participantsNCT05190172
What this trial is testing

PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas

Who this might be right for
OligodendrogliomaOligodendroglioma, AnaplasticDiffuse Astrocytoma, IDH-Mutant
Oslo University Hospital 225
Testing effectiveness (Phase 2)Active Not RecruitingNCT03953898
What this trial is testing

Using the Anticancer Drug Olaparib to Treat Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome With an Isocitrate Dehydrogenase (IDH) Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+4 more
National Cancer Institute (NCI) 14
Early research (Phase 1)Not Yet RecruitingNCT07629089
What this trial is testing

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

Who this might be right for
Brain Cancer
Megan Mantica 24
Not applicableUnknownNCT05595863
What this trial is testing

Correlation Between SPECT/CT and IDH Mutation in Brain Glioma

Who this might be right for
Brain Glioma
Assiut University 40
Early research (Phase 1)WithdrawnNCT04955938
What this trial is testing

Fedratinib With IDH Inhibition in Advanced-Phase, IDH-Mutated Ph-Negative Myeloproliferative Neoplasms

Who this might be right for
IDH MutationIDH1 MutationIDH2 Gene Mutation+2 more
University of Chicago
Testing effectiveness (Phase 2)Looking for participantsNCT06776250
What this trial is testing

Study of How Safe and Effective Tarlatamab is in Brain Cancers

Who this might be right for
Astrocytic TumorOligodendroglial Tumor
University Health Network, Toronto 44
Not applicableLooking for participantsNCT03684109
What this trial is testing

Non-invasive Glioma Characterization Through Molecular Imaging

Who this might be right for
GliomaBrain TumorPrimary Brain Tumor+2 more
University of Miami 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03991832
What this trial is testing

Study of Olaparib and Durvalumab in IDH-Mutated Solid Tumors

Who this might be right for
GliomaCholangiocarcinomaSolid Tumor+1 more
University Health Network, Toronto 58
Testing effectiveness (Phase 2)Active Not RecruitingNCT06478212
What this trial is testing

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

Who this might be right for
IDH1-mutant GliomaIDH2-mutant Glioma
Institut de Recherches Internationales Servier 51
Testing effectiveness (Phase 2)Study completedNCT03925246
What this trial is testing

Efficacy of Nivolumab for Recurrent IDH Mutated High-Grade Gliomas

Who this might be right for
High Grade GliomaBrain Cancer
Assistance Publique - Hôpitaux de Paris 43
Testing effectiveness (Phase 2)Looking for participantsNCT05345002
What this trial is testing

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Who this might be right for
GliomaIDH MutationAstrocytoma+1 more
Stephen Bagley, MD, MSCE 55
Testing effectiveness (Phase 2)Looking for participantsNCT05588141
What this trial is testing

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Who this might be right for
Brain TumorCancer
National Cancer Institute (NCI) 96
Testing effectiveness (Phase 2)UnknownNCT02209428
What this trial is testing

A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas

Who this might be right for
AstrocytomaOligodendrogliomaOligoastrocytoma
Huashan Hospital 54
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