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Results for “IDH Mutation”

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Showing 20 of 0 results

Not applicableNot Yet RecruitingNCT07439302
What this trial is testing

Monitoring of Neurological Symptoms, Treatment Tolerance, and Quality of Life Using the Resilience PRO Electronic Patient-reported Outcome Application in Patients With IDH-mutated Glioma

Who this might be right for
OncologyGlioma
Assistance Publique - Hôpitaux de Paris 80
Early research (Phase 1)Active Not RecruitingNCT03528642
What this trial is testing

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 2Astrocytoma, IDH-Mutant, Grade 3
National Cancer Institute (NCI) 23
Very early researchUnknownNCT02766270
What this trial is testing

CCRT With Temozolomide Versus RT Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas

Who this might be right for
Grade II/III Glioma
Beijing Tiantan Hospital 30
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Early research (Phase 1)Looking for participantsNCT07089641
What this trial is testing

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

Who this might be right for
GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more
Jonsson Comprehensive Cancer Center 50
Early research (Phase 1)Active Not RecruitingNCT02381886
What this trial is testing

IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

Who this might be right for
Advanced Malignancies That Harbor IDHR132 Mutations
Novartis Pharmaceuticals 166
Not applicableLooking for participantsNCT04233788
What this trial is testing

Metabolic Characterization of Space Occupying Lesions of the Brain

Who this might be right for
Brain TumorGliomaIDH Mutation
Insel Gruppe AG, University Hospital Bern 55
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Study completedNCT02719574
What this trial is testing

Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation

Who this might be right for
Acute Myeloid LeukemiaAcute Myelogenous LeukemiaMyelodysplastic Syndrome
Forma Therapeutics, Inc. 336
Not applicableUnknownNCT06481345
What this trial is testing

Characterization of Myeloproliferative Neoplasia With a Mutated IDH, SRSF2 or SF3B1 Allele (CARPEDIEM)

Who this might be right for
Myeloproliferative Disorders
University Hospital, Brest 300
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Not applicableStudy completedNCT06620926
What this trial is testing

Impact of IDH Mutation and Adjuvant Chemo(radio)therapy on Survival Outcome in Grade II/III Astrocytoma

Who this might be right for
AstrocytomaAstrocytic TumorsAstrocytoma of Brain
asmaa salama ibrahim 811
Early research (Phase 1)Study completedNCT05441514
What this trial is testing

Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Recurrent Acute Myeloid LeukemiaRefractory Acute Myeloid Leukemia
City of Hope Medical Center 3
Not applicableUnknownNCT04369287
What this trial is testing

Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIDH2 Gene Mutation
Istituto Clinico Humanitas 654
Testing effectiveness (Phase 2)Looking for participantsNCT07260175
What this trial is testing

Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 Cholangiocarcinoma

Who this might be right for
CholangiocarcinomaIDH Mutation
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 40
Early research (Phase 1)Ended earlyNCT04762602
What this trial is testing

HMPL-306 in Advanced Solid Tumors With IDH Mutations

Who this might be right for
Isocitrate Dehydrogenase Gene Mutation
Hutchmed 42
Large-scale testing (Phase 3)Ended earlyNCT03763422
What this trial is testing

Trial in Low Grade Glioma Patients: Wait or Treat

Who this might be right for
Low-grade GliomaTemozolomidePhase III+1 more
European Organisation for Research and Treatment of Cancer - EORTC 19
Not applicableStudy completedNCT04304300
What this trial is testing

Radiotherapy in IDH Mutated Glioma: Evaluation of Late Outcomes

Who this might be right for
Astrocytoma, Grade IIAstrocytoma, Grade IIIOligodendroglioma+1 more
Erasmus Medical Center 80
Testing effectiveness (Phase 2)Active Not RecruitingNCT04458272
What this trial is testing

DS-1001b in Patients With Chemotherapy- and Radiotherapy-Naive IDH1 Mutated WHO Grade II Glioma

Who this might be right for
WHO Grade II Glioma
Daiichi Sankyo Co., Ltd. 25
Very early researchLooking for participantsNCT06636162
What this trial is testing

Window of Opportunity Study of DSP-0390 in Gliomas

Who this might be right for
Glioma, MalignantIDH Mutation
Washington University School of Medicine 20
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