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Results for “IDH Mutation”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02677922
What this trial is testing

Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Celgene 130
Not applicableUnknownNCT05593809
What this trial is testing

Single Photon Emission Computed Tomography/Computed Tomography With Pentavalent 99mTc Dimercaptosuccinic Acid in Patients With Brain Glioma; Correlation With IDH Mutation

Who this might be right for
Brain Glioma
Assiut University 40
Very early researchActive Not RecruitingNCT05406700
What this trial is testing

Niraparib In Recurrent IDH 1/2 Gliomas

Who this might be right for
Low-grade GliomaIDH2 Gene MutationRecurrent Glioma+2 more
Massachusetts General Hospital 16
Large-scale testing (Phase 3)Looking for participantsNCT06387069
What this trial is testing

Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Hutchmed 316
Early research (Phase 1)Active Not RecruitingNCT04603001
What this trial is testing

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+1 more
Eli Lilly and Company 260
Large-scale testing (Phase 3)Looking for participantsNCT07215910
What this trial is testing

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

Who this might be right for
Astrocytoma, IDH-Mutant, Grade 3
Alliance for Clinical Trials in Oncology 408
Testing effectiveness (Phase 2)Looking for participantsNCT07417761
What this trial is testing

Tuvusertib in Astrocytoma With ATRX Mutation

Who this might be right for
Astrocytoma
Grupo Español de Investigación en Neurooncología 56
Not applicableStudy completedNCT07017790
What this trial is testing

Amino Acid PET to Assess the Efficacy of IDH Inhibitor Treatments for IDH Mutated Gliomas

Who this might be right for
Glioma
Central Hospital, Nancy, France 22
Early research (Phase 1)Active Not RecruitingNCT02632708
What this trial is testing

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia (AML)Untreated AMLAML Arising From Myelodysplastic Syndrome (MDS)+2 more
Institut de Recherches Internationales Servier 153
Not applicableStudy completedNCT01385150
What this trial is testing

Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia

Who this might be right for
Leukemia
Eastern Cooperative Oncology Group 220
Very early researchStudy completedNCT05851378
What this trial is testing

Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma

Who this might be right for
Adult Gliomas, Mixed
Robert Bok, MD, PhD 13
Not applicableLooking for participantsNCT07405372
What this trial is testing

Construction and Application of an IDH Mutation-Targeted PET/MRI Imaging Framework for Precision Diagnosis of Gliomas

Who this might be right for
Glioma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 10
Early research (Phase 1)Active Not RecruitingNCT03749187
What this trial is testing

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

Who this might be right for
GlioblastomaIDH1 Gene MutationIDH2 Gene Mutation+7 more
University of California, San Francisco 78
Not applicableLooking for participantsNCT07547163
What this trial is testing

Patient Voice in the Treatment of Low-grade Gliomas: Use of Patient-reported Outcomes, Vorasidenib and Radiotherapy Compared

Who this might be right for
GliomaGlioma of BrainLow Grade Glioma of Brain+2 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 90
Early research (Phase 1)Looking for participantsNCT02074839
What this trial is testing

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia (AML)Untreated AMLOther IDH1-mutated Positive Hematologic Malignancies+1 more
Institut de Recherches Internationales Servier 291
Not applicableNot Yet RecruitingNCT07469735
What this trial is testing

Vorasidenib Guided by AGX PET in Recurrent/Low-grade Glioma

Who this might be right for
GliomaDiffuse GliomaRecurrent Gliomas
Huashan Hospital 10
Testing effectiveness (Phase 2)WithdrawnNCT02977689
What this trial is testing

Trial of IDH305 in IDH1 Mutant Grade II or III Glioma

Who this might be right for
Glioma
NYU Langone Health
Very early researchWithdrawnNCT05061251
What this trial is testing

Surgical Window of Opportunity Study of Orally Administered BAY 2402234 in Recurrent Glioma

Who this might be right for
GliomaIDH Mutation
University of Texas Southwestern Medical Center
Large-scale testing (Phase 3)Not Yet RecruitingNCT07712757
What this trial is testing

Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma

Who this might be right for
Grade 2 Glioma (Astrocytoma or Oligodendroglioma) With an IDH1 MutationAstrocytoma IDH Mutant Grade 2Oligodendroglioma+2 more
Nuvation Bio Inc. 140
Early research (Phase 1)Looking for participantsNCT06666712
What this trial is testing

Chronic CED of TPT for Recurrent Malignant Glioma

Who this might be right for
Brain Tumor, RecurrentMalignant Glioma (WHO Grade III or IV)IDH1/IDH2 Mutation
Jeffrey N. Bruce 6
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