Testing effectiveness (Phase 2)Study completedNCT03561870What this trial is testingOlaparib in Recurrent IDH-mutant GliomaWho this might be right forRecurrent IDHMutant High Grade Glioma Hospices Civils de Lyon 35
Large-scale testing (Phase 3)Active Not RecruitingNCT06780930What this trial is testingPhase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 MutationWho this might be right forResidual or Recurrent Grade 2 IDH Mutant Glioma Servier 57
Not applicableLooking for participantsNCT07832734What this trial is testingMetabolomics and Transcriptomics of Low- and High-Grade GliomasWho this might be right forIDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07832123What this trial is testingSafusidenib for Patients With Newly Diagnosed IDH1-mutant CNS WHO Grade 3 Oligodendroglioma and Astrocytoma - a Single Arm Phase II StudyWho this might be right forGlioma : Oligodendroglioma or Astrocytoma University of Zurich 20
Not applicableNot Yet RecruitingNCT06368934What this trial is testingSub-lobectomy for IDH Wild-type and TERT Promoter Mutant GlioblastomaWho this might be right forGliomaGlioblastoma Huashan Hospital 326
Early research (Phase 1)Study completedNCT04908176What this trial is testingA Drug-drug Interaction Study of Avapritinib and MidazolamWho this might be right forGastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid Tumors+1 more Blueprint Medicines Corporation 10
Not applicableNot Yet RecruitingNCT07789678What this trial is testingEpidemiological Profile of Patients With IDH-Mutant Diffuse Gliomas Diagnosed From 2021 in BrazilWho this might be right forDiffuse GliomaIDH-mutant Gliomas Latin American Cooperative Oncology Group 350
Not applicableStudy completedNCT07673666What this trial is testingGliomaAI-Astro23: MRI-Based Detection of IDH Mutant Astrocytoma (Grade 2 and 3)Who this might be right forGliomaGlioma (Diagnosis)Astrocytoma+4 more Deep Learning Institute of Radiological Sciences 1,372
Not applicableNot Yet RecruitingNCT07710131What this trial is testingNeurocognitive Assessment CNSL and LGGWho this might be right forPCNSLBrain TumorCognitive Dysfunction+2 more Dana-Farber Cancer Institute 36
Post-approval studies (Phase 4)Study completedNCT06625047What this trial is testingComparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral ChemotherapyWho this might be right forAstrocytoma, IDH-MutantGlioblastomaGlioma+1 more Mayo Clinic 30
Early research (Phase 1)Looking for participantsNCT05879367What this trial is testingEvaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or AstrocytomaWho this might be right forGlioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme+4 more Orbus Therapeutics, Inc. 66
Not applicableLooking for participantsNCT05190172What this trial is testingPRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmasWho this might be right forOligodendrogliomaOligodendroglioma, AnaplasticDiffuse Astrocytoma, IDH-Mutant Oslo University Hospital 225
Early research (Phase 1)Looking for participantsNCT07223034What this trial is testing177Lu-PSMA-617 in People With GliomasWho this might be right forGliomaDiffuse Astrocytoma, IDH-Wildtype (Grade 2-4)Glioblastoma, IDH-wildtype+3 more Memorial Sloan Kettering Cancer Center 20
Early research (Phase 1)Not Yet RecruitingNCT07629089What this trial is testingVorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 MutationsWho this might be right forBrain Cancer Megan Mantica 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07120984What this trial is testingEvaluate the Safety and Efficacy of L19TNF With Alkylating Chemotherapy for Patients With Recurrent IDH-mutant Astrocytoma or OligodendrogliomaWho this might be right forGlioma Philogen S.p.A. 52
Early research (Phase 1)Enrolling By InvitationNCT06896110What this trial is testingIntrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade GliomaWho this might be right forGlioblastoma (GBM)Diffuse Midline Glioma (DMG)Astrocytoma, IDH-Mutant, Grade 4+2 more Andrew P. Groves 34
Not applicableStudy completedNCT05375318What this trial is testingBIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological LevelsWho this might be right forAstrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more Juan M Garcia-Gomez 50
Not applicableActive Not RecruitingNCT04975139What this trial is testingCognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State NetworksWho this might be right forGlioma Washington University School of Medicine 71
Early research (Phase 1)Looking for participantsNCT03922555What this trial is testingASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant GliomasWho this might be right forNeurological Cancer Massachusetts General Hospital 18
Not applicableLooking for participantsNCT07240662What this trial is testingVorasidenib in CNS WHO Grade 2 IDH-mutant Diffuse GliomaWho this might be right forGlioma iOMEDICO AG 150