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Results for “IDH-wildtype Gliomas”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Looking for participantsNCT05864534
What this trial is testing

Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma

Who this might be right for
Newly Diagnosed GlioblastomaGlioblastoma, Isocitric Dehydrogenase (IDH)-WildtypeGliosarcoma+1 more
Northwestern University 25
Early research (Phase 1)Ended earlyNCT04782609
What this trial is testing

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

Who this might be right for
Recurrent Glioblastoma Multiforme (GBM)Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype AstrocytomaGrade 3 or 4 Astrocytoma+1 more
Samus Therapeutics, Inc. 7
Not applicableLooking for participantsNCT05941234
What this trial is testing

Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma

Who this might be right for
Glioblastoma, IDH-wildtype
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 120
Early research (Phase 1)Looking for participantsNCT07544992
What this trial is testing

Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rα2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas

Who this might be right for
Recurrent Astrocytoma, IDH-Mutant, Grade 4Recurrent Glioblastoma, IDH-Wildtype
City of Hope Medical Center 24
Testing effectiveness (Phase 2)Looking for participantsNCT06319027
What this trial is testing

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Who this might be right for
Glioblastoma, IDH-Wildtype
ECOG-ACRIN Cancer Research Group 100
Testing effectiveness (Phase 2)Looking for participantsNCT07301268
What this trial is testing

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

Who this might be right for
Glioblastoma, IDH-WildtypeProgressive Astrocytoma, IDH-Mutant, Grade 4Progressive Glioblastoma+6 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Temporarily pausedNCT04677049
What this trial is testing

Study of Niacin in Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
AHS Cancer Control Alberta 59
Not applicableLooking for participantsNCT05326334
What this trial is testing

THERApeutic Outcomes Related to Gut microBIOME in Glioblastoma (GBM) Patients Receiving Chemo-radiation (THERABIOME-GBM)

Who this might be right for
Glioblastoma, IDH-wildtype
Ottawa Hospital Research Institute 20
Testing effectiveness (Phase 2)Looking for participantsNCT07185880
What this trial is testing

The Safety and Tolerability of MT-125 in GBM Patients

Who this might be right for
Glioblastoma (GBM)
Myosin Therapeutics Inc. 36
Testing effectiveness (Phase 2)Study completedNCT03779230
What this trial is testing

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse

Who this might be right for
Glioma of Brain
Philogen S.p.A. 20
Not applicableLooking for participantsNCT07374692
What this trial is testing

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

Who this might be right for
Recurrent CNS TumorsBrain CancerGliomas+3 more
National Cancer Institute (NCI) 80
Not applicableLooking for participantsNCT06623565
What this trial is testing

Extensive Resection of Malignant Brain Tumors Using Advanced Imaging Techniques

Who this might be right for
GlioblastomaAstrocytoma, IDH-Mutant, Grade 4
Amsterdam UMC, location VUmc 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07604285
What this trial is testing

Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma

Who this might be right for
Glioblastoma
Myosin Therapeutics Inc. 36
Testing effectiveness (Phase 2)Looking for participantsNCT05765812
What this trial is testing

Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeAstrocytoma, Grade III
Debiopharm International SA 116
Early research (Phase 1)Not Yet RecruitingNCT07422363
What this trial is testing

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma, IDH-WildtypeRecurrent GliosarcomaRecurrent WHO Grade 4 Glioma
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07620548
What this trial is testing

Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas

Who this might be right for
GlioblastomaGlioblastoma, IDH-wildtypeGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Washington University School of Medicine 99
Large-scale testing (Phase 3)Not Yet RecruitingNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Testing effectiveness (Phase 2)Ended earlyNCT03897491
What this trial is testing

PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastoma

Who this might be right for
Glioblastoma
photonamic GmbH & Co. KG 17
Not applicableLooking for participantsNCT06430424
What this trial is testing

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Who this might be right for
Relapsed CancerGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
University Hospital, Bordeaux 40
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
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