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Results for “IDH-wildtype Gliomas”

97 trials

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Showing 20 of 97 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07758062
What this trial is testing

Levetiracetam Extended-Release Plus Stupp Protocol for Hypoxic IDH-Wildtype Glioblastoma

Who this might be right for
Glioblastoma
Tianjin Medical University General Hospital 140
Early research (Phase 1)Active Not RecruitingNCT03011671
What this trial is testing

Study of Acetazolamide With Temozolomide in Adults With Newly Diagnosed or Recurrent Malignant Glioma

Who this might be right for
Malignant Glioma of Brain
University of Chicago 10
Testing effectiveness (Phase 2)Looking for participantsNCT05929495
What this trial is testing

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

Who this might be right for
Glioblastoma, IDH-wildtypeMetforminMalignancies
University of Milano Bicocca 25
Not applicableLooking for participantsNCT06146725
What this trial is testing

The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)

Who this might be right for
GlioblastomaGlioblastoma, IDH-wildtypeGlioblastoma Multiforme+2 more
Jasper Gerritsen 564
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06258018
What this trial is testing

Niraparib and Temozolomide in Patients Glioblastoma

Who this might be right for
Glioma, Malignant
Armando Santoro, MD 86
Not applicableLooking for participantsNCT07111195
What this trial is testing

Feasibility of ONCOhabitats for Surgical and Treatment Planning in IDH-Wildtype Glioblastoma (SINUE)

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Juan M Garcia-Gomez 140
Testing effectiveness (Phase 2)Looking for participantsNCT04945148
What this trial is testing

Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide

Who this might be right for
Glioblastoma, IDH-wildtype
Hopital Foch 640
Testing effectiveness (Phase 2)Study completedNCT03779230
What this trial is testing

Safety and Efficacy of L19TNF in Patients With Isocitrate Dehydrogenase (IDH) Wildtype WHO Grade III / IV Glioma at First Relapse

Who this might be right for
Glioma of Brain
Philogen S.p.A. 20
Testing effectiveness (Phase 2)Looking for participantsNCT04623931
What this trial is testing

Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas

Who this might be right for
Anaplastic Astrocytoma, IDH-WildtypeAnaplastic OligoastrocytomaAnaplastic Oligodendroglioma+6 more
M.D. Anderson Cancer Center 40
Very early researchUnknownNCT02766270
What this trial is testing

CCRT With Temozolomide Versus RT Alone in Patients With IDH Wild-type/TERT Promoter Mutation Grade II/III Gliomas

Who this might be right for
Grade II/III Glioma
Beijing Tiantan Hospital 30
Large-scale testing (Phase 3)Looking for participantsNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Very early researchLooking for participantsNCT07655869
What this trial is testing

[177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma

Who this might be right for
Recurrent High-Grade GliomasRecurrent Glioblastoma IDH Wildtype
Beijing Tiantan Hospital 24
Testing effectiveness (Phase 2)Looking for participantsNCT06319027
What this trial is testing

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Who this might be right for
Glioblastoma, IDH-Wildtype
ECOG-ACRIN Cancer Research Group 100
Testing effectiveness (Phase 2)UnknownNCT04614493
What this trial is testing

Innovative SonoCloud-9 Device for Blood Brain Barrier Opening in First Line Temozolomide Glioblastoma Patients.

Who this might be right for
Initial Radiological Diagnosis Eligible for Tumor ResectionInitial Radiological Diagnosis Compatible With Newly Diagnosed Glioblastoma (IDH Wild-type)Eligible for the Standard of Care Including Concurrent Temoradiation and Adjuvant Temozolomide
Assistance Publique - Hôpitaux de Paris 66
Early research (Phase 1)Study completedNCT06095375
What this trial is testing

Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM Patients

Who this might be right for
Glioblastoma, IDH-wildtypeMGMT-Methylated Glioblastoma
Istituto Oncologico Veneto IRCCS 21
Not applicableLooking for participantsNCT07832734
What this trial is testing

Metabolomics and Transcriptomics of Low- and High-Grade Gliomas

Who this might be right for
IDH Wildtype GlioblastomaIDH Mutant Lower-Grade Gliomas
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 220
Testing effectiveness (Phase 2)Ended earlyNCT03897491
What this trial is testing

PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastoma

Who this might be right for
Glioblastoma
photonamic GmbH & Co. KG 17
Early research (Phase 1)Looking for participantsNCT07089641
What this trial is testing

ERAS-801 for the Treatment of Resectable and Progressive or Recurrent or Elderly Newly Diagnosed IDH Wildtype Grade IV Glioblastoma or Gliosarcoma With an EGFR Amplification or Mutation, ERAS801-SARG Trial

Who this might be right for
GlioblastomaGlioblastoma, IDH-WildtypeGliosarcoma+3 more
Jonsson Comprehensive Cancer Center 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT05859334
What this trial is testing

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Who this might be right for
Recurrent GliomaRecurrent WHO Grade 2 GliomaRecurrent WHO Grade 3 Glioma+1 more
National Cancer Institute (NCI) 30
Not applicableLooking for participantsNCT06273176
What this trial is testing

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Who this might be right for
Glioblastoma, IDH-wildtypeGlioblastomaGlioblastoma Multiforme of Brain+6 more
Erasmus Medical Center 225
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