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Results for “IDH1-Mutated Malignancies”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07304011
What this trial is testing

Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent

Who this might be right for
Acute Myeloid Leukemia
University of California, Davis 28
Testing effectiveness (Phase 2)Looking for participantsNCT06717958
What this trial is testing

Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation

Who this might be right for
AMLMDS
Technische Universität Dresden 76
Large-scale testing (Phase 3)Active Not RecruitingNCT05987358
What this trial is testing

A Clinical Study of TQB3454 Tablets in the Treatment of Advanced Biliary Carcinoma.

Who this might be right for
Biliary Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 165
Early research (Phase 1)Study completedNCT02454634
What this trial is testing

Phase I Trial of IDH1 Peptide Vaccine in IDH1R132H-mutated Grade III-IV Gliomas

Who this might be right for
Glioma
National Center for Tumor Diseases, Heidelberg 39
Early research (Phase 1)Active Not RecruitingNCT07411586
What this trial is testing

Phase 1/1b Trial Of Olutasidenib And Ziftomenib For NPM1 And IDH1 Co-Mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
M.D. Anderson Cancer Center 32
Early research (Phase 1)Looking for participantsNCT06291987
What this trial is testing

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

Who this might be right for
Myeloproliferative Neoplasms
University of Chicago 18
Early research (Phase 1)Looking for participantsNCT06543381
What this trial is testing

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic Syndrome
City of Hope Medical Center 15
Early research (Phase 1)Study completedNCT02492737
What this trial is testing

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic SyndromeHematologic Malignancies
Agios Pharmaceuticals, Inc. 46
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Very early researchStudy completedNCT05577416
What this trial is testing

AB-218 in Patients With IDH1 Mutated Low Grade Glioma

Who this might be right for
Glioma
Melbourne Health 14
Testing effectiveness (Phase 2)Looking for participantsNCT04493164
What this trial is testing

CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Gene MutationsMyelodysplastic SyndromeMyeloproliferative Neoplasm+2 more
M.D. Anderson Cancer Center 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT02677922
What this trial is testing

Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Celgene 130
Large-scale testing (Phase 3)Looking for participantsNCT05907057
What this trial is testing

An Open-label Phase 3b Study of Ivosidenib in Combination With Azacitidine in Adult Patients Newly Diagnosed With IDH1m Acute Myeloid Leukemia (AML) Ineligible for Intensive Induction Chemotherapy.

Who this might be right for
Acute Myeloid Leukemia (AML)
Servier Affaires Médicales 245
Testing effectiveness (Phase 2)Looking for participantsNCT05588141
What this trial is testing

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Who this might be right for
Brain TumorCancer
National Cancer Institute (NCI) 96
Early research (Phase 1)Study completedNCT03564821
What this trial is testing

IDH1 Inhibition Using Ivosidenib as Maintenance Therapy for IDH1-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation

Who this might be right for
IDH1 Mutation Myeloid Neoplasms
Massachusetts General Hospital 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT02704858
What this trial is testing

Safety and Efficacy Study in Recurrent or Progressive Grade III or IV IDH1 Mutated Glioma

Who this might be right for
Glioblastoma Multiforme
Neonc Technologies, Inc. 49
Not applicableStudy completedNCT04423094
What this trial is testing

Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas

Who this might be right for
Glioma
University Hospital, Montpellier 8
Not applicableLooking for participantsNCT07315542
What this trial is testing

Diagnostic and Therapeutic Targets in Cartilaginous Tumours

Who this might be right for
ChondrosarcomasCartilage Tumours
St. Anne's University Hospital Brno, Czech Republic 300
Not applicableUnknownNCT02597335
What this trial is testing

Non Invasive Detection of IDH1/2 Mutation in Gliomas

Who this might be right for
GliomaIDH1/IDH2 Mutation
Assistance Publique - Hôpitaux de Paris 40
Testing effectiveness (Phase 2)Looking for participantsNCT07007949
What this trial is testing

A New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIvosidenib
The First Affiliated Hospital of Soochow University 42
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