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Results for “Immune Checkpoint Blockade”

150 trials

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Showing 20 of 150 results

Early research (Phase 1)Study completedNCT03666273
What this trial is testing

Phase 1 Study of BAY1905254 - An Early Clinical Research Study to Evaluate a New Drug Called Bapotulimab (BAY1905254) in the Expansion Cohort in Combination With Pembrolizumab in Head and Neck Cancer That Has Returned or is Discovered to be Metastatic and is Expressing PDL1.

Who this might be right for
Advanced Solid TumorHead and Neck Squamous Cell Carcinoma
Bayer 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03076554
What this trial is testing

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Who this might be right for
ThymomaThymic Carcinoma
National Cancer Institute (NCI) 56
Testing effectiveness (Phase 2)WithdrawnNCT03130764
What this trial is testing

Durvalumab and Tremelimumab for Adjuvant Therapy of Resected NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Columbia University
Early research (Phase 1)Looking for participantsNCT05937295
What this trial is testing

FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined with Immune Checkpoint Inhibition

Who this might be right for
Fibrolamellar Hepatocellular Carcinoma
University Hospital Tuebingen 20
Not applicableLooking for participantsNCT03291028
What this trial is testing

Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma

Who this might be right for
Renal Cell CarcinomaUrothelial CarcinomaBladder Cancer+2 more
Fox Chase Cancer Center 16
Early research (Phase 1)Active Not RecruitingNCT06514898
What this trial is testing

Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With Medulloblastoma

Who this might be right for
Recurrent Group 3 MedulloblastomaRecurrent Group 4 (Non-SHH/Non-WNT) Medulloblastoma
University of Florida 12
Testing effectiveness (Phase 2)WithdrawnNCT07011849
What this trial is testing

Study of Lenvatinib Plus Pembrolizumab in IO Refractory mRCC Patients With Brain Metastases

Who this might be right for
Renal Cell CarcinomaBrain Metastasis
M.D. Anderson Cancer Center
Large-scale testing (Phase 3)Active Not RecruitingNCT04444921
What this trial is testing

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Who this might be right for
Anal Basaloid CarcinomaAnal Canal Cloacogenic CarcinomaMetastatic Anal Squamous Cell Carcinoma+4 more
National Cancer Institute (NCI) 205
Testing effectiveness (Phase 2)Study completedNCT03007407
What this trial is testing

Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy

Who this might be right for
Colorectal Cancer Metastatic
NSABP Foundation Inc 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT04454528
What this trial is testing

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

Who this might be right for
Breast Cancer
Abramson Cancer Center at Penn Medicine 27
Testing effectiveness (Phase 2)UnknownNCT02557321
What this trial is testing

PV-10 in Combination With Pembrolizumab for Treatment of Metastatic Melanoma

Who this might be right for
Melanoma
Provectus Biopharmaceuticals, Inc. 50
Early research (Phase 1)Looking for participantsNCT05430009
What this trial is testing

Liver SBRT in Combination With Immune Checkpoint Inhibition in Patients With Metastatic Non-small Cell Lung Cancer

Who this might be right for
Liver MetastasesNon-small Cell Lung Cancer
VA Ann Arbor Healthcare System 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT04417660
What this trial is testing

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Who this might be right for
Thymic Epithelial TumorRecurrent ThymomaThymic Cancer
National Cancer Institute (NCI) 9
Not applicableLooking for participantsNCT06599619
What this trial is testing

Effects of Anti-PD1 Adjuvant Checkpoint Blockade Immunotherapy on Atypical/Dysplastic Nevi

Who this might be right for
Melanoma
John Kirkwood 30
Testing effectiveness (Phase 2)Study completedNCT03365791
What this trial is testing

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Who this might be right for
Small Cell Lung CancerGastric AdenocarcinomaEsophageal Adenocarcinoma+5 more
Novartis Pharmaceuticals 76
Testing effectiveness (Phase 2)WithdrawnNCT04042506
What this trial is testing

SBRT as a Vaccination for Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Not applicableLooking for participantsNCT07167251
What this trial is testing

Management of Immune Checkpoint Inhibition-related Hepatitis Using Low-dose Corticosteroids

Who this might be right for
Immune Related Adverse EventsImmune-Mediated HepatitisCancer
University Hospital, Basel, Switzerland 63
Not applicableEnded earlyNCT04222426
What this trial is testing

89Zr-atezolizumab PET Scan and Lobular Breast Cancer

Who this might be right for
Lobular Metastatic Breast Cancer
University Medical Center Groningen 1
Testing effectiveness (Phase 2)Looking for participantsNCT06843551
What this trial is testing

The Miami "EMPIRE" Trial - Eradication of Metastatic Pancreatic Cancer With Immuno-Radiation

Who this might be right for
Metastatic Pancreatic Ductal AdenocarcinomaMetastatic Pancreatic Cancer
Benjamin Spieler 20
Early research (Phase 1)Active Not RecruitingNCT04620603
What this trial is testing

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

Who this might be right for
Cutaneous Malignant MelanomaRenal Cell CancerUrothelial Cancer of Renal Pelvis
Case Comprehensive Cancer Center 5
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