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Results for “Immune Checkpoint Blockade”

150 trials

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Showing 20 of 150 results

Testing effectiveness (Phase 2)Ended earlyNCT04880382
What this trial is testing

Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients

Who this might be right for
Non Small Cell Lung Cancer
Institut Bergonié 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT05089370
What this trial is testing

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

Who this might be right for
Malignant Melanoma
University of Colorado, Denver 8
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Testing effectiveness (Phase 2)Study completedNCT04577807
What this trial is testing

LUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory Melanoma

Who this might be right for
Melanoma
Istari Oncology, Inc. 27
Large-scale testing (Phase 3)Study completedNCT03063450
What this trial is testing

CheckpOiNt Blockade For Inhibition of Relapsed Mesothelioma

Who this might be right for
Mesothelioma
University of Southampton 332
Testing effectiveness (Phase 2)Ended earlyNCT04166383
What this trial is testing

VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal CancerColorectal NeoplasmsColorectal Carcinoma+2 more
National Cancer Institute (NCI) 14
Testing effectiveness (Phase 2)Study completedNCT03749460
What this trial is testing

Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

Who this might be right for
Metastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the LungSalivary Gland Carcinoma+4 more
University of Washington 20
Early research (Phase 1)Active Not RecruitingNCT04620603
What this trial is testing

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

Who this might be right for
Cutaneous Malignant MelanomaRenal Cell CancerUrothelial Cancer of Renal Pelvis
Case Comprehensive Cancer Center 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06538935
What this trial is testing

SBRT Combined With Adbelimumab and Apatinib for Perioperative and Conversion Therapy of Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaSBRTImmune Checkpoint Blockade+1 more
Fujian Cancer Hospital 80
Testing effectiveness (Phase 2)WithdrawnNCT06410534
What this trial is testing

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

Who this might be right for
Colorectal CancerGastroesophageal Cancer
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Active Not RecruitingNCT04444921
What this trial is testing

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Who this might be right for
Anal Basaloid CarcinomaAnal Canal Cloacogenic CarcinomaMetastatic Anal Squamous Cell Carcinoma+4 more
National Cancer Institute (NCI) 205
Not applicableLooking for participantsNCT04807127
What this trial is testing

A Single-cell Approach to Identify Biomarkers of Pulmonary Toxicity for Immune Checkpoint Blockade

Who this might be right for
Pneumonitis, InterstitialImmunotherapyImmune-related Adverse Events
Universitaire Ziekenhuizen KU Leuven 60
Testing effectiveness (Phase 2)Looking for participantsNCT07130032
What this trial is testing

Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade

Who this might be right for
Metastatic Non-small Cell Lung Cancer (NSCLC)Metastatic Cutaneous Melanoma
EuroCityClinic LLC 90
Testing effectiveness (Phase 2)Study completedNCT02196961
What this trial is testing

Adjuvant Therapy of Completely Resected Merkel Cell Carcinoma With Immune Checkpoint Blocking Antibodies vs Observation

Who this might be right for
Merkel Cell Carcinoma
Prof. Dr. med. Dirk Schadendorf 180
Early research (Phase 1)Active Not RecruitingNCT03955978
What this trial is testing

TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer

Who this might be right for
Endometrial CancerCancer of the Endometrium
Washington University School of Medicine 10
Early research (Phase 1)Looking for participantsNCT05937295
What this trial is testing

FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined with Immune Checkpoint Inhibition

Who this might be right for
Fibrolamellar Hepatocellular Carcinoma
University Hospital Tuebingen 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT06754501
What this trial is testing

Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary

Who this might be right for
Cancer
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Looking for participantsNCT05915442
What this trial is testing

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer

Who this might be right for
Oligometastatic Prostate Cancer
Catherine Spina 23
Large-scale testing (Phase 3)Looking for participantsNCT06794775
What this trial is testing

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Who this might be right for
Malignant Melanoma Stage III
Hildur Helgadottir 128
Testing effectiveness (Phase 2)Active Not RecruitingNCT02621151
What this trial is testing

Pembrolizumab (MK3475), Gemcitabine, and Concurrent Hypofractionated Radiation Therapy for Muscle-Invasive Urothelial Cancer of the Bladder

Who this might be right for
Muscle-invasive Urothelial Cancer of the Bladder
NYU Langone Health 60
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