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Results for “Immune Checkpoint Blockade”

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Showing 20 of 0 results

Very early researchLooking for participantsNCT05141474
What this trial is testing

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors

Who this might be right for
Epithelial Tumors, MalignantMalignant Solid Tumor
Vall d'Hebron Institute of Oncology 10
Testing effectiveness (Phase 2)Study completedNCT03953235
What this trial is testing

A Personalized Cancer Vaccine Targeting Shared Neoantigens

Who this might be right for
Non-Small Cell Lung CancerColorectal CancerPancreatic Cancer+2 more
Gritstone bio, Inc. 39
Large-scale testing (Phase 3)Active Not RecruitingNCT05141721
What this trial is testing

A Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Neoplasms
Seattle Project Corporation 700
Testing effectiveness (Phase 2)UnknownNCT04913922
What this trial is testing

Relatlimab With Nivolumab and 5-Azacytidine for the Treatment of AML

Who this might be right for
Acute Myeloid Leukemia
Ludwig-Maximilians - University of Munich 30
Testing effectiveness (Phase 2)WithdrawnNCT06410534
What this trial is testing

A Phase II Study Evaluating an Organ Preservation Strategy Using Immune Checkpoint Blockade for Participants With Primary Colorectal or Gastroesophageal Cancer

Who this might be right for
Colorectal CancerGastroesophageal Cancer
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT06754501
What this trial is testing

Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary

Who this might be right for
Cancer
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04417660
What this trial is testing

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Who this might be right for
Thymic Epithelial TumorRecurrent ThymomaThymic Cancer
National Cancer Institute (NCI) 9
Not applicableNot Yet RecruitingNCT07586293
What this trial is testing

Histidine and Immunotherapy Response in Colorectal Cancer

Who this might be right for
Colorectal Cancer
Jing-yuan Fang, MD, Ph. D 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03937830
What this trial is testing

Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects With Hepatocellular Carcinoma or Biliary Tract Carcinoma

Who this might be right for
Hepatocellular CancerHepatocellular CarcinomaMetastatic Hepatocellular Carcinoma
National Cancer Institute (NCI) 27
Large-scale testing (Phase 3)Looking for participantsNCT06794775
What this trial is testing

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Who this might be right for
Malignant Melanoma Stage III
Hildur Helgadottir 128
Testing effectiveness (Phase 2)Study completedNCT03749460
What this trial is testing

Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

Who this might be right for
Metastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the LungSalivary Gland Carcinoma+4 more
University of Washington 20
Testing effectiveness (Phase 2)Ended earlyNCT04880382
What this trial is testing

Integrative Analysis of Tumor Microenvironment and Optimization of Immunotherapy Duration in NSCL Cancer Patients

Who this might be right for
Non Small Cell Lung Cancer
Institut Bergonié 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT05089370
What this trial is testing

Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma

Who this might be right for
Malignant Melanoma
University of Colorado, Denver 8
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Not applicableActive Not RecruitingNCT04447651
What this trial is testing

Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)

Who this might be right for
Metastatic Solid TumorSF3B1 Gene MutationSpliceosome Mutation+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT04454528
What this trial is testing

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

Who this might be right for
Breast Cancer
Abramson Cancer Center at Penn Medicine 27
Testing effectiveness (Phase 2)Looking for participantsNCT03026140
What this trial is testing

Neoadjuvant Immune Checkpoint Inhibition and Novel IO Combinations in Early-stage Colon Cancer

Who this might be right for
Colon Carcinoma
The Netherlands Cancer Institute 353
Early research (Phase 1)Active Not RecruitingNCT04620603
What this trial is testing

Low-Dose-Rate Brachytherapy Combined With Immune Checkpoint Inhibition in Cancer

Who this might be right for
Cutaneous Malignant MelanomaRenal Cell CancerUrothelial Cancer of Renal Pelvis
Case Comprehensive Cancer Center 5
Testing effectiveness (Phase 2)UnknownNCT02557321
What this trial is testing

PV-10 in Combination With Pembrolizumab for Treatment of Metastatic Melanoma

Who this might be right for
Melanoma
Provectus Biopharmaceuticals, Inc. 50
Early research (Phase 1)Ended earlyNCT03275597
What this trial is testing

Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Non-small Lung Cancer (NSCLC) With Dual Immune Checkpoint Inhibition

Who this might be right for
Non-small Cell Lung CancerNon-small Cell Lung Cancer Stage IV
University of Wisconsin, Madison 17
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