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Results for “Immune Checkpoint Inhibition”

139 trials

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Showing 20 of 139 results

Testing effectiveness (Phase 2)Study completedNCT03365791
What this trial is testing

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Who this might be right for
Small Cell Lung CancerGastric AdenocarcinomaEsophageal Adenocarcinoma+5 more
Novartis Pharmaceuticals 76
Testing effectiveness (Phase 2)WithdrawnNCT04650490
What this trial is testing

SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer

Who this might be right for
Brain MetastasesNon Small Cell Lung Cancer
Duke University
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Testing effectiveness (Phase 2)Study completedNCT03749460
What this trial is testing

Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

Who this might be right for
Metastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the LungSalivary Gland Carcinoma+4 more
University of Washington 20
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056895
What this trial is testing

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Who this might be right for
Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8Clinical Stage IV Merkel Cell Carcinoma AJCC v8Merkel Cell Carcinoma
University of Washington 12
Testing effectiveness (Phase 2)Looking for participantsNCT05915442
What this trial is testing

Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer

Who this might be right for
Oligometastatic Prostate Cancer
Catherine Spina 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT03076554
What this trial is testing

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Who this might be right for
ThymomaThymic Carcinoma
National Cancer Institute (NCI) 56
Early research (Phase 1)WithdrawnNCT03802747
What this trial is testing

Immunotherapy Combined With Y-90 and SBRT for Colorectal Liver Metastases

Who this might be right for
Colorectal Cancer
University of Colorado, Denver
Not applicableLooking for participantsNCT03291028
What this trial is testing

Analysis of Primary and Metastatic Tumors in Patients With Renal Cell Carcinoma and Urothelial Carcinoma

Who this might be right for
Renal Cell CarcinomaUrothelial CarcinomaBladder Cancer+2 more
Fox Chase Cancer Center 16
Testing effectiveness (Phase 2)Study completedNCT02684461
What this trial is testing

Phase II Trial of Sequential Consolidation With Pembrolizumab Followed by Nab-paclitaxel

Who this might be right for
Non Small Cell Lung Cancer
UNC Lineberger Comprehensive Cancer Center 20
Not applicableStudy completedNCT03356470
What this trial is testing

Pilot Study of Biomarkers of Response to Immune Checkpoint Blockade in Metastatic Melanoma

Who this might be right for
Melanoma
University of Wisconsin, Madison 5
Testing effectiveness (Phase 2)Study completedNCT04247165
What this trial is testing

Nivolumab, Ipilimumab and Chemoradiation in Pancreatic Cancer.

Who this might be right for
Borderline Resectable, Locally Advanced or Metastatic Pancreatic Cancer
Herlev Hospital 55
Not applicableLooking for participantsNCT07064681
What this trial is testing

The Real-world Study of AK104 Combining With TACE for Resectable Hepatocellular Carcinoma (MORNING)

Who this might be right for
Resectable Hepatocellular Carcinoma With High Risk of Recurrence
Sun Yat-sen University 100
Testing effectiveness (Phase 2)Ended earlyNCT04560686
What this trial is testing

Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer

Who this might be right for
Resectable Lung Non-Small Cell CarcinomaStage I Lung Cancer AJCC v8Stage IA1 Lung Cancer AJCC v8+8 more
M.D. Anderson Cancer Center 2
Testing effectiveness (Phase 2)Study completedNCT04166383
What this trial is testing

VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC)

Who this might be right for
Metastatic Colorectal CancerColorectal NeoplasmsColorectal Carcinoma+2 more
National Cancer Institute (NCI) 14
Testing effectiveness (Phase 2)Looking for participantsNCT03942328
What this trial is testing

Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer

Who this might be right for
Stage III Hepatocellular Carcinoma AJCC v8Stage III Intrahepatic Cholangiocarcinoma AJCC v8Stage IV Hepatocellular Carcinoma AJCC v8+3 more
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT04997850
What this trial is testing

The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectableTransarterial ChemoembolizationTyrosine Kinase Inhibitor+1 more
Xinrui Zhu，MD 142
Testing effectiveness (Phase 2)Ended earlyNCT05123586
What this trial is testing

A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
Eli Lilly and Company 85
Testing effectiveness (Phase 2)Study completedNCT03007407
What this trial is testing

Study of Durvalumab and Tremelimumab After Radiation for Microsatellite Stable Metastatic Colorectal Cancer Progressing on Chemotherapy

Who this might be right for
Colorectal Cancer Metastatic
NSABP Foundation Inc 33
Early research (Phase 1)Active Not RecruitingNCT06524570
What this trial is testing

Treatment of Cancer with Immune Checkpoint Inhibition Therapy Boosted by High Intensity Focused Ultrasound Histotripsy

Who this might be right for
CancerMetastatic Cancer
UMC Utrecht 24
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