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Results for “Immune Checkpoint Therapy”

457 trials

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Showing 20 of 457 results

Large-scale testing (Phase 3)Looking for participantsNCT06989112
What this trial is testing

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Who this might be right for
Endometrial Cancer
AstraZeneca 600
Testing effectiveness (Phase 2)Looking for participantsNCT03645928
What this trial is testing

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Who this might be right for
Metastatic MelanomaSquamous Cell Carcinoma of the Head and NeckNon-small Cell Lung Cancer
Iovance Biotherapeutics, Inc. 245
Post-approval studies (Phase 4)Not Yet RecruitingNCT07004335
What this trial is testing

Efficacy and Safety of Iparomlimab and Tuvonralimab Injection in Combination With Bevacizumab After Progression on Anti-PD-(L)1 Therapy in Advanced Melanoma: A Prospective, Single-Arm, Exploratory Clinical Study

Who this might be right for
PD-(L)1CTLA-4Advanced Melanoma+3 more
Hebei Medical University Fourth Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06576921
What this trial is testing

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Who this might be right for
Stomach NeoplasmsImmune Checkpoint Inhibitors
Xijing Hospital 116
Early research (Phase 1)Ended earlyNCT03237572
What this trial is testing

Focused Ultrasound and Pembrolizumab in Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Patrick Dillon, MD 13
Not applicableStudy completedNCT05221398
What this trial is testing

Adjuvant Immune Checkpoint Inhibitors in Postoperative Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Guangxi Medical University 517
Very early researchLooking for participantsNCT05141474
What this trial is testing

Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors

Who this might be right for
Epithelial Tumors, MalignantMalignant Solid Tumor
Vall d'Hebron Institute of Oncology 10
Not applicableStudy completedNCT05332821
What this trial is testing

TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC

Who this might be right for
Hepatocellular Carcinoma
Zhongda Hospital 1,244
Not applicableStudy completedNCT03140137
What this trial is testing

Immune Checkpoint Inhibitors and Pre-existing Autoimmune Diseases

Who this might be right for
Autoimmune DiseasesAdvanced Cancer
University Hospital, Brest 112
Testing effectiveness (Phase 2)Looking for participantsNCT05284539
What this trial is testing

Efficacy of Platinum-based Chemotherapy Plus Immune Checkpoint Inhibitors for EGFR/ALK/ROS1 Mutant Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Hunan Province Tumor Hospital 760
Testing effectiveness (Phase 2)Looking for participantsNCT07281924
What this trial is testing

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

Who this might be right for
Metastatic MelanomaLiver Metastases
University of Wisconsin, Madison 15
Testing effectiveness (Phase 2)Looking for participantsNCT07238881
What this trial is testing

Dalpiciclib Plus Camrelizumab for HCC Patients Who Have Previously Received ICI Treatment

Who this might be right for
Hepatocellulcar Carcinoma
Sun Yat-sen University 30
Testing effectiveness (Phase 2)Looking for participantsNCT07495215
What this trial is testing

A Clinical Study on the Safety, Tolerability and Efficacy of Neoantigen-based Personalized mRNA Therapy iNeo-Vac-R01 Plus PD-1 Inhibitor in Adjuvant Treatment of Liver Cancer Post Radical Resection

Who this might be right for
Hepatocellular Carcinoma (HCC)
Yinghua Xu 20
Large-scale testing (Phase 3)Looking for participantsNCT06103864
What this trial is testing

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 625
Testing effectiveness (Phase 2)Looking for participantsNCT07213830
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Ipsen 102
Early research (Phase 1)Ended earlyNCT05695898
What this trial is testing

XmAb23104 (PD1 X ICOS) and XmAb22841 (CTLA-4 X LAG3) in Treating Melanoma Prior Immune Checkpoint Inhibitor Therapy

Who this might be right for
Metastatic MelanomaAdvanced Melanoma
University of California, San Francisco 6
Testing effectiveness (Phase 2)Study completedNCT02601014
What this trial is testing

Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7

Who this might be right for
Prostate CancerRecurrent Prostate CarcinomaStage IV Prostate Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 32
Testing effectiveness (Phase 2)WithdrawnNCT04058145
What this trial is testing

AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Cancer
Massachusetts General Hospital
Testing effectiveness (Phase 2)Looking for participantsNCT03259867
What this trial is testing

Combination of TATE and PD-1 Inhibitor in Liver Cancer

Who this might be right for
Hepatocellular CarcinomaGastric Cancer
Teclison Ltd. 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT03228667
What this trial is testing

QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors

Who this might be right for
Non-Small Cell Lung CancerSmall Cell Lung CancerUrothelial Carcinoma+10 more
ImmunityBio, Inc. 40
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