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Results for “Immune Checkpoint Therapy”

504 trials

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Showing 20 of 504 results

Large-scale testing (Phase 3)Looking for participantsNCT06340568
What this trial is testing

A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer

Who this might be right for
Endometrial Cancer
BioNTech SE 480
Not applicableNot Yet RecruitingNCT07665697
What this trial is testing

Analysis of Efficacy and Outcomes of Immunotherapy for Malignant Tumors: A Prospective Non-interventional Clinical Study

Who this might be right for
NeoplasmsDrug TherapyImmune Checkpoint Inhibitors (ICIs)
Sichuan University 500
Not applicableUnknownNCT06309862
What this trial is testing

Immune Checkpoint Inhibitor Therapy for Cancer and Risk of Myocarditis or Cardiomyopathy

Who this might be right for
Cardio-OncologyCardiomyopathy Due to Drug
Sunnybrook Health Sciences Centre 15
Testing effectiveness (Phase 2)Looking for participantsNCT06630611
What this trial is testing

Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL)

Who this might be right for
MelanomaNon Small Cell Lung CancerCervical Cancer
Vall d'Hebron Institute of Oncology 40
Testing effectiveness (Phase 2)Looking for participantsNCT07381075
What this trial is testing

A Phase II Clinical Trial of Anti-EGFR Antibody-drug Conjugate (ADC) Combined With or Without Immune Checkpoint Inhibitors in the Neoadjuvant Treatment of Resectable Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
West China Hospital 90
Early research (Phase 1)WithdrawnNCT06290622
What this trial is testing

PD-1, LAG-3 and TIM-3 Checkpoint Blockade in DLBCL

Who this might be right for
Diffuse Large B Cell LymphomaLymphoma, B-CellLymphoma, Follicular
University of Alabama at Birmingham
Testing effectiveness (Phase 2)Looking for participantsNCT06675201
What this trial is testing

Neoantigen Vaccines in Esophageal Squamous Cell Carcinoma

Who this might be right for
Esophageal Squamous Cell Carcinoma (ESCC)Neoantigen-loaded Dendritic Cell VaccineImmune Checkpoint Inhibitors (ICIs)
Sichuan University 165
Testing effectiveness (Phase 2)Study completedNCT03988036
What this trial is testing

A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1)

Who this might be right for
Breast Cancer
Women's Cancer Study Group GmbH 46
Not applicableNot Yet RecruitingNCT07689812
What this trial is testing

Randomized Open-Label Trial Evaluating ctDNA-Guided Interruption Versus Standard of Care Immune-Checkpoint Inhibitor (ICI) Therapy In Patients With Advanced / Metastatic Solid Tumors.

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Cancer)NSCLC (Non-small Cell Lung Carcinoma)+12 more
Natera, Inc. 920
Large-scale testing (Phase 3)Looking for participantsNCT06958432
What this trial is testing

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 430
Not applicableEnded earlyNCT05812274
What this trial is testing

Apricity CARE to Improve ICI Outcomes of Ethnic/Racial Minority NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
Columbia University 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07267234
What this trial is testing

PRaG-1 Plus PRaG Therapy in Advanced Solid Tumors: A Prospective Clinical Trial (PRaG 10.0)

Who this might be right for
Solid CancerLymphopeniaRadiotherapy+1 more
Second Affiliated Hospital of Soochow University 65
Testing effectiveness (Phase 2)WithdrawnNCT05660421
What this trial is testing

Itacitinib for the Treatment Steroid Refractory Immune Related Adverse Events Arising From Immune Checkpoint Inhibitors

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
Douglas Johnson
Testing effectiveness (Phase 2)Active Not RecruitingNCT04957615
What this trial is testing

Nivolumab for the Treatment of Metastatic or Unresectable Solid Tumors With ARID1A Mutation and CXCL13 Expression

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Solid Neoplasm
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Testing effectiveness (Phase 2)Looking for participantsNCT05758389
What this trial is testing

Tislelizumab Combined APF Chemotherapy in the Treatment of Locally Advanced Head and Neck Tumors

Who this might be right for
Head and Neck Tumors
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 29
Not applicableActive Not RecruitingNCT06117891
What this trial is testing

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

Who this might be right for
Unresectable Hepatocellular Carcinoma
Bayer 300
Not applicableNot Yet RecruitingNCT07206511
What this trial is testing

Conversion Therapy Using TACE/HAIC With Anti-Angiogenic and Immunotherapy for Initially Unresectable Hepatocellular Carcinoma Achieving Complete Response or Resectability, Followed by Surgery or Continued Systemic Treatment: A Prospective Cohort Study

Who this might be right for
Unresectable Hepatocellular Carcinom
Shanghai Zhongshan Hospital 278
Not applicableStudy completedNCT06881433
What this trial is testing

Immune Checkpoint Inhibitors and Anti-vascular Endothelial Growth Factor Antibody/Tyrosine Kinase Inhibitors With or Without HAIC for Unresectable HCC With Portal Vein Tumor Thrombosis

Who this might be right for
Hepatocellular Carcinoma (HCC)
Zhongda Hospital 1,649
Testing effectiveness (Phase 2)Looking for participantsNCT06019130
What this trial is testing

Nivolumab in Children and Adults With Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal CarcinomaNasopharyngeal CancerNasopharyngeal Neoplasms+1 more
German Society for Pediatric Oncology and Hematology GPOH gGmbH 57
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