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Results for “Immune Checkpoint Therapy”

448 trials

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Showing 20 of 448 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT05445648
What this trial is testing

Comprehensive Bladder Preservation Therapy on Patients With Muscle Invasive Bladder Cancer

Who this might be right for
Urinary Bladder Neoplasms
First Affiliated Hospital Xi'an Jiaotong University 65
Testing effectiveness (Phase 2)Active Not RecruitingNCT06879717
What this trial is testing

Roginolisib (IOA-244) in Combination With Dostarlimab With or Without Docetaxel in Metastatic Non Small-cell Lung Cancer (NSCLC) Patients

Who this might be right for
Non-Squamous Non-Small Cell Lung Cancer (NSCLC)Advanced Non Squamous NSCLC
iOnctura 45
Testing effectiveness (Phase 2)Looking for participantsNCT04592211
What this trial is testing

Pembrolizumab, Olaparib, Recurrent/Advanced Gastric and Gastro-esophageal Junction(GEJ) Cancer

Who this might be right for
Gastric Cancer Stage IV
Yonsei University 71
Testing effectiveness (Phase 2)Active Not RecruitingNCT04706715
What this trial is testing

LAG3 PET Imaging in Advanced Solid Tumors

Who this might be right for
Metastatic Solid Tumor
University Medical Center Groningen 41
Testing effectiveness (Phase 2)Study completedNCT03365791
What this trial is testing

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Who this might be right for
Small Cell Lung CancerGastric AdenocarcinomaEsophageal Adenocarcinoma+5 more
Novartis Pharmaceuticals 76
Testing effectiveness (Phase 2)Looking for participantsNCT06772623
What this trial is testing

Study to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic Alterations

Who this might be right for
Non Small Cell Lung Carcinoma
AbbVie 252
Testing effectiveness (Phase 2)Ended earlyNCT04214418
What this trial is testing

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Who this might be right for
Gastrointestinal Cancer
Columbia University 27
Testing effectiveness (Phase 2)Study completedNCT03749460
What this trial is testing

Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers

Who this might be right for
Metastatic Malignant Neoplasm in the BoneMetastatic Malignant Neoplasm in the LungSalivary Gland Carcinoma+4 more
University of Washington 20
Large-scale testing (Phase 3)Looking for participantsNCT06958432
What this trial is testing

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 430
Early research (Phase 1)Study completedNCT04084951
What this trial is testing

Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Adult Solid Tumor
SQZ Biotechnologies 30
Early research (Phase 1)Study completedNCT03884556
What this trial is testing

TTX-030 Single Agent and in Combination With Immunotherapy or Chemotherapy for Patients With Advanced Cancers

Who this might be right for
Solid TumorLymphoma
Trishula Therapeutics, Inc. 56
Not applicableNot Yet RecruitingNCT06242522
What this trial is testing

Fertility and Pregnancy After Avelumab Treatment

Who this might be right for
Gestational Trophoblastic TumoursImmune Checkpoint Inhibitors
Hospices Civils de Lyon 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT06056895
What this trial is testing

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Who this might be right for
Unresectable Clinical Stage III Merkel Cell Carcinoma AJCC v8Clinical Stage IV Merkel Cell Carcinoma AJCC v8Merkel Cell Carcinoma
University of Washington 12
Testing effectiveness (Phase 2)Looking for participantsNCT03899428
What this trial is testing

Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBsAg+ Advanced Stage HCC

Who this might be right for
Hepatocellular Carcinoma
Humanity & Health Medical Group Limited 30
Large-scale testing (Phase 3)Looking for participantsNCT05335928
What this trial is testing

Abatacept in Immune Checkpoint Inhibitor Myocarditis

Who this might be right for
Myocarditis AcuteCancer
Massachusetts General Hospital 390
Testing effectiveness (Phase 2)Looking for participantsNCT07330037
What this trial is testing

TALENT Study: Phase II Trial of Adjuvant L-TIL Plus Tislelizumab in Resectable NSCLC Without pCR After Neoadjuvant Chemoimmunotherapy

Who this might be right for
NSCLC
Tianjin Medical University Cancer Institute and Hospital 41
Not applicableLooking for participantsNCT06669377
What this trial is testing

TACE Combined With ICIs Plus MTT After 125I Irradiation Stent Placement in HCC With Main PVTT.

Who this might be right for
Hepatocellular Carcinoma
Zhongda Hospital 444
Not applicableUnknownNCT05285579
What this trial is testing

Biomarkers of Angiogenesis for Response to Therapeutic Combination in Advanced or Metastatic Kidney Cancer

Who this might be right for
Renal Cell CarcinomaRenal CancerRenal Cancer Metastatic
Assistance Publique - Hôpitaux de Paris 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT04305145
What this trial is testing

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

Who this might be right for
Melanoma Stage IIIMelanoma Stage IVSkin Cancer Stage III+4 more
Massachusetts General Hospital 42
Not applicableLooking for participantsNCT06197581
What this trial is testing

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer

Who this might be right for
Breast Cancer, Familial MaleRadiotherapy; ComplicationsChemotherapeutic Toxicity+5 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 148
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