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Results for “Immunoglobulin Light Chain (AL) Amyloidosis”

131 trials

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Showing 20 of 131 results

Large-scale testing (Phase 3)Study completedNCT01078454
What this trial is testing

Melphalan and Dexamethasone With or Without Bortezomib in Treating Patients With Previously Untreated Systemic Light-Chain Amyloidosis

Who this might be right for
Light Chain Deposition DiseasePrimary Systemic Amyloidosis
National Cancer Institute (NCI) 11
Testing effectiveness (Phase 2)Looking for participantsNCT06158854
What this trial is testing

Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Immunoglobulin Light Chain (AL) Amyloidosis Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion

Who this might be right for
Immunoglobulin Light Chain (AL) Amyloidosis
AbbVie 76
Testing effectiveness (Phase 2)Looking for participantsNCT07081646
What this trial is testing

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

Who this might be right for
Relapsed AL AmyloidosisRefractory AL AmyloidosisLight Chain Amyloidosis+1 more
Alexion Pharmaceuticals, Inc. 91
Testing effectiveness (Phase 2)WithdrawnNCT01531751
What this trial is testing

High Cut-off Hemodialysis in Patients With Advanced Cardiac AL Amyloidosis and End Stage Renal Disease

Who this might be right for
Primary Amyloidosis of Light Chain Type
Fondazione IRCCS Policlinico San Matteo di Pavia
Testing effectiveness (Phase 2)Study completedNCT00002849
What this trial is testing

S9628 Dexamethasone Plus Interferon Alfa in Treating Patients With Primary Systemic Amyloidosis

Who this might be right for
Multiple Myeloma
SWOG Cancer Research Network 93
Testing effectiveness (Phase 2)Study completedNCT03499808
What this trial is testing

S1702 Isatuximab in Treating Patients With Relapsed or Refractory Primary Amyloidosis

Who this might be right for
Amorphous, Eosinophilic, and Acellular DepositConstipationDiarrhea+10 more
SWOG Cancer Research Network 43
Not applicableLooking for participantsNCT01758042
What this trial is testing

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders

Who this might be right for
Chronic Kidney DiseaseAcute Myeloid Leukemia (AML)Acute Lymphoblastic Leukemia (ALL)+14 more
Massachusetts General Hospital 10
Testing effectiveness (Phase 2)Study completedNCT00091260
What this trial is testing

CC-5013 With or Without Dexamethasone in Treating Patients With Primary Systemic Amyloidosis

Who this might be right for
Multiple Myeloma
Vaishali Sanchorawala 82
Not applicableLooking for participantsNCT06627309
What this trial is testing

Rapid DFLC Response Predict CHR in AL Amyloidosis

Who this might be right for
Systemic AL Amyloidosis
Peking University People's Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT03618537
What this trial is testing

Ixazomib Maintenance Study in Patients With AL Amyloidosis

Who this might be right for
AL Amyloidosis
Memorial Sloan Kettering Cancer Center 17
Testing effectiveness (Phase 2)WithdrawnNCT05486481
What this trial is testing

Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)

Who this might be right for
AL AmyloidosisLight Chain (AL) AmyloidosisSystemic Light Chain Disease
Alfred Chung, MD
Not applicableStudy completedNCT02716103
What this trial is testing

Assessment of Minimal Residual Disease (MRD) After Antineoplastic Treatment in Patients With AL Amyloidosis

Who this might be right for
Amyloidosis
Boston Medical Center 45
Early research (Phase 1)Study completedNCT00807872
What this trial is testing

Radioimmunoimaging of AL Amyloidosis

Who this might be right for
Primary Amyloidosis
University of Tennessee 40
Testing effectiveness (Phase 2)Ended earlyNCT03154047
What this trial is testing

Study in Subjects With Light Chain (AL) Amyloidosis

Who this might be right for
AL Amyloidosis
Prothena Biosciences Ltd. 80
Not applicableLooking for participantsNCT06192979
What this trial is testing

Optimize First-line Treatment for AL Amyloidosis With t (11; 14)

Who this might be right for
Amyloidosis; SystemicAL Amyloidosis
Jin Lu, MD 41
Testing effectiveness (Phase 2)Study completedNCT02632786
What this trial is testing

The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis

Who this might be right for
AL Amyloidosis
Prothena Biosciences Ltd. 129
Large-scale testing (Phase 3)Looking for participantsNCT05184088
What this trial is testing

Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis

Who this might be right for
Cardiac AmyloidosisAL AmyloidosisATTR Amyloidosis
Life Molecular Imaging GmbH 200
Testing effectiveness (Phase 2)Study completedNCT01677286
What this trial is testing

Safety and Effect of Doxycycline in Patients With Amyloidosis

Who this might be right for
Amyloidosis
Boston University 25
Testing effectiveness (Phase 2)Study completedNCT00002810
What this trial is testing

High-Dose Melphalan Followed by Peripheral Stem Cell Transplant in Treating Patients With Amyloidosis

Who this might be right for
Multiple Myeloma and Plasma Cell Neoplasm
Temple University
Testing effectiveness (Phase 2)Study completedNCT04304144
What this trial is testing

Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis

Who this might be right for
AL Amyloidosis
Alexion Pharmaceuticals, Inc. 25
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