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Results for “Immunotherapy Resistance”

181 trials

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Showing 20 of 181 results

Testing effectiveness (Phase 2)Looking for participantsNCT05592626
What this trial is testing

A Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsGenital Neoplasm, FemaleUrogenital Neoplasms+11 more
Marengo Therapeutics, Inc. 366
Testing effectiveness (Phase 2)Ended earlyNCT04936230
What this trial is testing

Immunotherapy With or Without Radiation Therapy for Metastatic Urothelial Cancer

Who this might be right for
Metastatic Urothelial CarcinomaPlatinum-Resistant Urothelial CarcinomaStage IV Bladder Cancer AJCC v8
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Looking for participantsNCT06463665
What this trial is testing

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

Who this might be right for
Advanced Non-squamous Non-small-cell Lung CancerAdvanced Squamous Non-Small Cell Lung CarcinomaMetastatic Non-squamous Non Small Cell Lung Cancer+5 more
Genelux Corporation 142
Large-scale testing (Phase 3)Ended earlyNCT02654587
What this trial is testing

OSE2101 Versus Chemotherapy in HLA-A2 Positive Patients With Advanced NSCLC After Immune Checkpoint Inhibitor Failure

Who this might be right for
Non Small Cell Lung Cancer
OSE Immunotherapeutics 219
Not applicableStudy completedNCT03848676
What this trial is testing

Genomic and Phenotypic Determinants of Resistance to Immunotherapies in Multiple Myeloma

Who this might be right for
Multiple Myeloma
University of Turin, Italy 40
Testing effectiveness (Phase 2)Study completedNCT02759588
What this trial is testing

Olvi-Vec Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Who this might be right for
Ovarian CancerPeritoneal CarcinomatosisFallopian Tube Cancer
Genelux Corporation 46
Testing effectiveness (Phase 2)WithdrawnNCT00348842
What this trial is testing

Newcastle Disease Virus (NDV) for Cancer Patients Resistant to Conventional Anti-cancer Modalities

Who this might be right for
Metastatic CancerNewcastle Disease Virus (NDV)
Hadassah Medical Organization
Not applicableLooking for participantsNCT06156150
What this trial is testing

The Role of B7-H4 in Tumor Vaccine

Who this might be right for
Glioma
Huashan Hospital 160
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07681297
What this trial is testing

Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System Disease

Who this might be right for
Advanced Solid Tumor CancerTriple-Negative Breast Cancer (TNBC)CNS Disease+1 more
National University Hospital, Singapore 154
Not applicableStudy completedNCT03985696
What this trial is testing

Exosomes and Immunotherapy in Non-Hodgkin B-cell Lymphomas

Who this might be right for
Lymphoma, B-cell, Aggressive Non-Hodgkin (B-NHL)
University Hospital, Limoges 90
Testing effectiveness (Phase 2)Ended earlyNCT05243524
What this trial is testing

Maveropepimut-S (MVP-S) and Low-Dose CPA in Patients With Platinum-Resistant Ovarian Cancer

Who this might be right for
Platinum-resistant Epithelial Ovarian Cancer
ImmunoVaccine Technologies, Inc. (IMV Inc.) 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT07138885
What this trial is testing

A Phase II, Single-Arm, Prospective Trial on the Efficacy and Safety of QL1706 Combination Regimen as Second-Line Therapy for Targeted-Immunotherapy-Resistant Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma (HCC)Second Line Treatment
Sun Yat-sen University 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT05990543
What this trial is testing

Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer

Who this might be right for
Recurrent or Metastatic Colorectal Cancer
Korea University Anam Hospital 59
Early research (Phase 1)Ended earlyNCT05274451
What this trial is testing

Investigate LYL797 in Adults With Solid Tumors

Who this might be right for
Triple Negative Breast CancerTNBC - Triple-Negative Breast CancerNon-small Cell Lung Cancer+20 more
Lyell Immunopharma, Inc. 57
Testing effectiveness (Phase 2)Ended earlyNCT01420965
What this trial is testing

Sipuleucel-T, CT-011, and Cyclophosphamide for Advanced Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Augusta University 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT03607890
What this trial is testing

Study of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inhibitor

Who this might be right for
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 TherapyMSI-H Tumors
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Testing effectiveness (Phase 2)Looking for participantsNCT05690048
What this trial is testing

Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)

Who this might be right for
ImmunotherapyHCC - Hepatocellular Carcinoma
Michael Dill 48
Early research (Phase 1)Looking for participantsNCT04221542
What this trial is testing

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
Prostate Cancer
Amgen 479
Testing effectiveness (Phase 2)Looking for participantsNCT03591276
What this trial is testing

Phase 1b Study of Pegylated Liposomal Doxorubicin and Pembrolizumab in Endocrine-resistant Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Shaare Zedek Medical Center 15
Early research (Phase 1)Active Not RecruitingNCT04165941
What this trial is testing

Novel Gamma-Delta (γδ)T Cell Therapy for Treatment of Patients With Newly Diagnosed Glioblastoma

Who this might be right for
Brain Tumor Adult
University of Alabama at Birmingham 22
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