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Results for “In Expansion: Melanoma, Non-small Cell Lung Cancer”

57 trials

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Showing 20 of 57 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04083599
What this trial is testing

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Who this might be right for
Malignant Solid TumorNon-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)+3 more
Genmab 350
Early research (Phase 1)Active Not RecruitingNCT02817633
What this trial is testing

TSR-022 in Participants With Advanced Solid Tumors (AMBER)

Who this might be right for
Neoplasms
Tesaro, Inc. 463
Early research (Phase 1)Active Not RecruitingNCT05653882
What this trial is testing

A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors

Who this might be right for
Solid TumorNon Small Cell Lung CancerMelanoma+2 more
Asher Biotherapeutics, Inc. 552
Early research (Phase 1)Ended earlyNCT04261439
What this trial is testing

A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab

Who this might be right for
In Escalation: All Patients With Solid Tumors and LymphomaIn Expansion: Melanoma, Non-small Cell Lung Cancer
Novartis Pharmaceuticals 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05275374
What this trial is testing

XP-102 and XP-102 in Combination With Trametinib in Advanced Solid Tumor Patients With a BRAF V600 Mutation

Who this might be right for
CancerBRAF V600 MutationMelanoma+3 more
Xynomic Pharmaceuticals, Inc. 221
Early research (Phase 1)Study completedNCT02573259
What this trial is testing

A Dose Escalation Study Of PF-06801591 In Melanoma, Head And Neck Cancer (SCCHN), Ovarian, Sarcoma, Non-Small Cell Lung Cancer, Urothelial Carcinoma or Other Solid Tumors

Who this might be right for
Part 1MELANOMASCCHN+6 more
Pfizer 147
Early research (Phase 1)Active Not RecruitingNCT05537740
What this trial is testing

A First-in-human Study to Learn How Safe the Study Drug BAY3375968, an Anti-CCR8 Antibody, is, When Given Alone or in Combination With Pembrolizumab, How it Affects the Body, How it Moves Into, Through, and Out of the Body, and to Find the Best Dose in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bayer 129
Early research (Phase 1)Ended earlyNCT06052852
What this trial is testing

Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies

Who this might be right for
Triple Negative Breast CancerClear Cell Renal Cell CarcinomaOvarian Cancer+4 more
Bolt Biotherapeutics, Inc. 17
Testing effectiveness (Phase 2)Study completedNCT05259696
What this trial is testing

Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)

Who this might be right for
OncologyMelanomaOvarian Cancer+14 more
Palleon Pharmaceuticals, Inc. 69
Testing effectiveness (Phase 2)Looking for participantsNCT05081609
What this trial is testing

Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+10 more
Ascendis Pharma Oncology Division A/S 345
Testing effectiveness (Phase 2)Looking for participantsNCT05267626
What this trial is testing

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Who this might be right for
Advanced Solid TumorMetastatic CancerCutaneous Melanoma+1 more
Aulos Bioscience, Inc. 159
Early research (Phase 1)Looking for participantsNCT05107674
What this trial is testing

NX-1607 in Adults With Advanced Malignancies

Who this might be right for
Ovarian Cancer, EpithelialGastric CancerGastroEsophageal Junction (GEJ) Cancer+11 more
Nurix Therapeutics, Inc. 345
Early research (Phase 1)Ended earlyNCT06285097
What this trial is testing

PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Who this might be right for
NeoplasmsNon-small-cell Lung CancerMelanoma+5 more
Pfizer 9
Early research (Phase 1)Ended earlyNCT06546553
What this trial is testing

Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines.

Who this might be right for
NeoplasmsNon-small-cell Lung CancerSquamous Cell Carcinoma of the Head and Neck+3 more
Pfizer 9
Testing effectiveness (Phase 2)Ended earlyNCT03361228
What this trial is testing

Evaluate the Safety, Tolerability, and Antitumor Activity of INCB001158 Plus Epacadostat, With or Without Pembrolizumab, in Advanced Solid Tumors

Who this might be right for
Solid Tumors
Incyte Corporation 5
Early research (Phase 1)Ended earlyNCT06448364
What this trial is testing

A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination

Who this might be right for
Advanced or Metastatic Solid TumorsNon-Small Cell Lung CancerColorectal Cancer+2 more
Pfizer 4
Testing effectiveness (Phase 2)Study completedNCT04068896
What this trial is testing

Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy

Who this might be right for
Pancreatic CancerMetastatic Castration-resistant Prostate CancerBladder Cancer+8 more
NGM Biopharmaceuticals, Inc 89
Testing effectiveness (Phase 2)Study completedNCT02988817
What this trial is testing

Enapotamab Vedotin (HuMax-AXL-ADC) Safety Study in Patients With Solid Tumors

Who this might be right for
Ovarian CancerCervical CancerEndometrial Cancer+5 more
Genmab 306
Early research (Phase 1)Ended earlyNCT04990479
What this trial is testing

Nous-PEV: a Novel Immunotherapy for Lung Cancer and Melanoma

Who this might be right for
Melanoma (Skin)Non-Small-Cell Lung Carcinoma
Nouscom SRL 7
Testing effectiveness (Phase 2)Study completedNCT02437136
What this trial is testing

Ph1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)

Who this might be right for
Non-Small Cell Lung CancerMelanomaMismatch Repair-Proficient Colorectal Cancer
Syndax Pharmaceuticals 191
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