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Results for “Inadequate Response”

437 trials

Showing 20 of 437 results

Large-scale testing (Phase 3)WithdrawnNCT04483687
What this trial is testing

Study to Evaluate the Efficacy and Safety of Filgotinib in Participants With Active Ankylosing Spondylitis Who Have an Inadequate Response to Biologic Disease-Modifying Antirheumatic Drug Therapy

Who this might be right for
Ankylosing Spondylitis
Gilead Sciences
Testing effectiveness (Phase 2)Study completedNCT01482221
What this trial is testing

Assess the Effect and Safety of AZD6765 in Patients With Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
AstraZeneca 542
Testing effectiveness (Phase 2)Study completedNCT06247735
What this trial is testing

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Who this might be right for
Primary Biliary Cholangitis
Kowa Research Institute, Inc. 46
Large-scale testing (Phase 3)Study completedNCT00767325
What this trial is testing

A Rheumatoid Arthritis Study to Assess Early Response to Abatacept+MTX as Defined by Improvement of Synovitis Measures by Power Doppler Ultrasonography

Who this might be right for
Rheumatoid Arthritis
Bristol-Myers Squibb 104
Not applicableEnded earlyNCT01196780
What this trial is testing

An Observational Study of MabThera/Rituxan (Rituximab) in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Anti-TNF Therapy (REPEAT)

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 1,240
Testing effectiveness (Phase 2)Study completedNCT05198310
What this trial is testing

Study to Assess the Safety, Pharmacokinetics, and Efficacy of KPL-404 in Participants With Rheumatoid Arthritis With Inadequate Response or Intolerance to at Least One Biologic Disease-modifying Anti-rheumatic Drug or a Janus Kinase Inhibitor

Who this might be right for
Arthritis, Rheumatoid
Kiniksa Pharmaceuticals, Ltd. 145
Large-scale testing (Phase 3)Study completedNCT03086343
What this trial is testing

Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Who this might be right for
Rheumatoid Arthritis (RA)
AbbVie 657
Testing effectiveness (Phase 2)Ended earlyNCT03093025
What this trial is testing

Evaluate the Safety and Efficacy of TS-121 as an Adjunctive Treatment for Major Depressive Disorder

Who this might be right for
Major Depressive Disorder
Taisho Pharmaceutical R&D Inc. 51
Large-scale testing (Phase 3)Study completedNCT01254331
What this trial is testing

An Open-label Study With Tocilizumab in Patients With Rheumatoid Arthritis in a Local Environment

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 51
Large-scale testing (Phase 3)Ended earlyNCT06514742
What this trial is testing

Aticaprant 10 mg as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy and Long-term Extension Treatment With Aticaprant

Who this might be right for
Depressive Disorder, MajorAnhedonia
Janssen Research & Development, LLC 101
Large-scale testing (Phase 3)Active Not RecruitingNCT05653219
What this trial is testing

Efficacy and Safety of Ianalumab Versus Placebo in Addition to Eltrombopag in Primary Immune Thrombocytopenia Patients Who Failed Steroids

Who this might be right for
Primary Immune Thrombocytopenia
Novartis Pharmaceuticals 152
Not applicableStudy completedNCT05841030
What this trial is testing

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

Who this might be right for
Depressive Disorder, Major
Janssen Research & Development, LLC 545
Large-scale testing (Phase 3)Ended earlyNCT01436175
What this trial is testing

SPD489 Adult Major Depressive Disorder (MDD) Open-label Safety and Tolerability Rollover Extension Study

Who this might be right for
Major Depressive Disorder
Shire 1,570
Large-scale testing (Phase 3)Study completedNCT03155347
What this trial is testing

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 340
Post-approval studies (Phase 4)Study completedNCT06616415
What this trial is testing

A Clinical Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Belumosudil in Chinese Adolescents With cGVHD Who Have Had an Inadequate Response to Glucocorticoids or Other Systemic Therapies

Who this might be right for
Chronic Graft Versus Host Disease
Sanofi 6
Post-approval studies (Phase 4)Study completedNCT00504777
What this trial is testing

MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Agents.

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 36
Testing effectiveness (Phase 2)Looking for participantsNCT07423533
What this trial is testing

Phase IIb Clinical Study to Assess the Efficacy and Safety of GenSci120 Injection in Patients With Moderately to Severely Active RA Who Have an Inadequate Response to at Least One DMARD

Who this might be right for
Rheumatoid Arthritis
Changchun GeneScience Pharmaceutical Co., Ltd. 450
Post-approval studies (Phase 4)Study completedNCT00934648
What this trial is testing

MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 15
Not applicableStudy completedNCT04877652
What this trial is testing

DR REGISTRY: Prospective Observational Study of ADHF Patients With Insufficient Response to Diuretics

Who this might be right for
Acute Decompensated Heart Failure
Revamp Medical Ltd. 6
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07660172
What this trial is testing

Ianalumab in Addition to Eltrombopag in Pediatric Patients With Primary ITP Who Failed Corticosteroids.

Who this might be right for
Primary Immune Thrombocytopenia (ITP)
Novartis Pharmaceuticals 36
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