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Results for “Inherited Mitochondrial Disease”

352 trials

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Showing 20 of 352 results

Testing effectiveness (Phase 2)Study completedNCT01856868
What this trial is testing

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

Who this might be right for
Becker Muscular Dystrophy
Craig McDonald, MD 7
Testing effectiveness (Phase 2)Study completedNCT00000766
What this trial is testing

CMV Retinitis Retreatment Trial

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 300
Not applicableLooking for participantsNCT06967831
What this trial is testing

Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells

Who this might be right for
Leigh Syndrome (Maternally Inherited, MILS)Leigh Syndrome (AR, AD, XR)
Charite University, Berlin, Germany 80
Testing effectiveness (Phase 2)Study completedNCT01965327
What this trial is testing

Interferon Gamma-1b in Friedreich Ataxia (FRDA)

Who this might be right for
Friedreich Ataxia
Children's Hospital of Philadelphia 12
Not applicableLooking for participantsNCT03475173
What this trial is testing

New Non-invasive Modalities for Assessing Retinal Structure and Function

Who this might be right for
Ischemic Optic NeuropathyBranch Retinal Artery OcclusionHemianopia+2 more
Randy Kardon 500
Large-scale testing (Phase 3)Study completedNCT00002070
What this trial is testing

Phase III Ganciclovir +/- rGM-CSF for AIDS-Related CMV Retinitis

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Schering-Plough
Testing effectiveness (Phase 2)Study completedNCT04513002
What this trial is testing

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis

Who this might be right for
Ataxia Telangiectasia
The University of Queensland 30
Not applicableStudy completedNCT00002251
What this trial is testing

A Multiple Dose Crossover Pharmacokinetics Study to Evaluate the Effects of Food on the Absorption of Oral Ganciclovir

Who this might be right for
Cytomegalovirus InfectionsHIV Infections
Hoffmann-La Roche 20
Not applicableUnknownNCT06324877
What this trial is testing

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside

Who this might be right for
Ataxia Telangiectasia
The University of Queensland 10
Early research (Phase 1)Study completedNCT00078481
What this trial is testing

Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia

Who this might be right for
Friedreich Ataxia
National Institute of Neurological Disorders and Stroke (NINDS) 16
Not applicableStudy completedNCT00002025
What this trial is testing

Open Label Ganciclovir Therapy for Sight- or Life-Threatening Cytomegalovirus Disease in the Immunocompromised Patient

Who this might be right for
Cytomegalovirus InfectionsCytomegalovirus RetinitisHIV Infections
Hoffmann-La Roche
Not applicableStudy completedNCT02745938
What this trial is testing

GDF-15 as a Biomarker for Mitochondrial Disease

Who this might be right for
Mitochondrial DiseaseMetabolic MyopathyMuscular Dystrophy
Rigshospitalet, Denmark 97
Not applicableStudy completedNCT00002135
What this trial is testing

An Open-Label Safety Study of Oral Ganciclovir Maintenance Treatment of CMV Retinitis in People With Limited Venous Access

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Hoffmann-La Roche
Testing effectiveness (Phase 2)Study completedNCT01962363
What this trial is testing

EPI-743 in Friedreich's Ataxia Point Mutations

Who this might be right for
Friedreich's Ataxia
University of South Florida 4
Large-scale testing (Phase 3)Study completedNCT04577352
What this trial is testing

Assess the Efficacy and Safety of Vatiquinone for the Treatment of Participants With Friedreich Ataxia

Who this might be right for
Friedreich Ataxia
PTC Therapeutics 146
Testing effectiveness (Phase 2)WithdrawnNCT03866954
What this trial is testing

Trial of Erythrocyte Encapsulated Thymidine Phosphorylase In Mitochondrial Neurogastrointestinal Encephalomyopathy

Who this might be right for
Mitochondrial DiseasesMetabolic DiseaseInborn Errors of Metabolism
St George's, University of London
Not applicableStudy completedNCT05555784
What this trial is testing

Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Argo Sante 12
Early research (Phase 1)Looking for participantsNCT06340685
What this trial is testing

Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency

Who this might be right for
Pyruvate Dehydrogenase Complex Deficiency
Jirair Krikor Bedoyan 6
Not applicableStudy completedNCT00002222
What this trial is testing

Valganciclovir in the Treatment of Cytomegalovirus (CMV) Retinitis in Patients With AIDS

Who this might be right for
Cytomegalovirus RetinitisHIV Infections
Hoffmann-La Roche 200
Not applicableStudy completedNCT05615571
What this trial is testing

Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants.

Who this might be right for
Neurodegeneration With Brain Iron Accumulation (NBIA)
University Hospital, Bordeaux 70
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