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Results for “Inhibition Enzyme”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Study completedNCT02220803
What this trial is testing

A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction

Who this might be right for
Obstructive Sleep ApneaSleep-Disordered BreathingBlood Pressure+1 more
Göteborg University 13
Large-scale testing (Phase 3)Looking for participantsNCT07555483
What this trial is testing

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

Who this might be right for
Alpha 1 Antitrypsin Deficiency
Grifols Therapeutics LLC 40
Testing effectiveness (Phase 2)Study completedNCT00732069
What this trial is testing

Study of Inflammation and Oxidative Stress in Persons Undergoing Dialysis

Who this might be right for
End Stage Renal Failure on DialysisComplication of Hemodialysis
Vanderbilt University 19
Early research (Phase 1)Study completedNCT01289756
What this trial is testing

Influence of Pharmacogenetic Factors, Paroxetine and Clarithromycin on Pharmacokinetics of Clomiphene

Who this might be right for
AnovulationDisorder Due Cytochrome P450 CYP2D6 VariantCytochrome P450 CYP3A Enzyme Deficiency
Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) 20
Large-scale testing (Phase 3)Ended earlyNCT00736294
What this trial is testing

Prevention of Atrial Fibrillation by Inhibition Conversion Enzyme (ICE) After Radiofrequency Ablation of Atrial Flutter

Who this might be right for
Atrial FibrillationAtrial Flutter
Centre Hospitalier Universitaire de Saint Etienne 198
Not applicableUnknownNCT06021262
What this trial is testing

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Who this might be right for
Neuroinflammatory ResponseNerve InjuryNerve Damage+3 more
Alexandria University 90
Post-approval studies (Phase 4)Study completedNCT00681226
What this trial is testing

Angiotensin Converting Enzyme (ACE) Inhibition and Peripheral Arterial Disease

Who this might be right for
Peripheral Arterial Disease
Bayside Health 200
Large-scale testing (Phase 3)Study completedNCT01297959
What this trial is testing

Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery

Who this might be right for
Infections
Excited States, LLC 503
Not applicableStudy completedNCT02130687
What this trial is testing

Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure

Who this might be right for
Type 2 Diabetes MellitusHypertension
Vanderbilt University 106
Testing effectiveness (Phase 2)Ended earlyNCT04575610
What this trial is testing

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

Who this might be right for
COVID-19
Yale University 7
Not applicableStudy completedNCT01091961
What this trial is testing

Study of Preoperative Management of Angiotensin Converting Enzyme Inhibitor (ACEi) and Angiotensin Receptor Blocker (ARB) Medications

Who this might be right for
Hypertension
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 200
Testing effectiveness (Phase 2)Study completedNCT05569759
What this trial is testing

Zetomipzomib (KZR-616) in Patients With Autoimmune Hepatitis (PORTOLA)

Who this might be right for
Autoimmune Hepatitis
Kezar Life Sciences, Inc. 24
Testing effectiveness (Phase 2)Study completedNCT00533039
What this trial is testing

SPLA2 Inhibition to Decrease Enzyme Release After PCI Trial

Who this might be right for
Coronary Artery Disease
University Health Network, Toronto 164
Early research (Phase 1)Study completedNCT03011463
What this trial is testing

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Who this might be right for
PharmacokineticsInhibition EnzymeDrug Interaction Potentiation
Dr. R. Pfleger Chemische Fabrik GmbH 24
Large-scale testing (Phase 3)Study completedNCT00113087
What this trial is testing

Trial of Angiotensin Converting Enzyme Inhibition in Infants With Single Ventricle--Pediatric Heart Network

Who this might be right for
Heart Defects, CongenitalHeart Failure, Congestive
National Heart, Lung, and Blood Institute (NHLBI) 230
Testing effectiveness (Phase 2)Study completedNCT01280006
What this trial is testing

Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans

Who this might be right for
Obstructive Sleep ApneaHypertensionCardiovascular Diseases+1 more
University of Calgary 12
Post-approval studies (Phase 4)Study completedNCT00269243
What this trial is testing

Management With Accupril Post Bypass Graft

Who this might be right for
CABG
Montreal Heart Institute
Not applicableNot Yet RecruitingNCT05133050
What this trial is testing

Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants

Who this might be right for
Alport Syndrome
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 510
Not applicableStudy completedNCT00212901
What this trial is testing

High Dose Ace Inhibitor Therapy Versus Combination of ACE and ARB Therapy

Who this might be right for
Diabetic Kidney Disease
Ottawa Hospital Research Institute 30
Testing effectiveness (Phase 2)Study completedNCT01118520
What this trial is testing

AARDVARK (Aortic Aneurysmal Regression of Dilation: Value of ACE-Inhibition on RisK)

Who this might be right for
Abdominal Aortic Aneurysm
Imperial College London 224
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