Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Initial Therapy”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT00456846
What this trial is testing

First Line Therapy for Patients With Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Celgene 123
Not applicableUnknownNCT05153603
What this trial is testing

Outcomes of First-line Olaparib Mono-maintenance therapy-a Multicenter, Retrospective Study Using Data From Real-world Clinical Setting

Who this might be right for
Ovarian Neoplasms
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 50
Testing effectiveness (Phase 2)Study completedNCT01562990
What this trial is testing

Phase Ib/II Study of the Efficacy and Safety of the R-CMC544/R-GEMOX Combination in Diffuse Lage B-cell Lymphoma at First or Second Relapse

Who this might be right for
Diffuse Large B-Cell Lymphoma
The Lymphoma Academic Research Organisation 11
Large-scale testing (Phase 3)Active Not RecruitingNCT03793179
What this trial is testing

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Who this might be right for
Lung Non-Squamous Non-Small Cell CarcinomaStage IIIB Lung Cancer AJCC v8Stage IIIC Lung Cancer AJCC v8+1 more
National Cancer Institute (NCI) 600
Not applicableNot Yet RecruitingNCT07543510
What this trial is testing

Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaAtezolizumab Plus BevacizumabTransarterial Chemoembolization
Third Affiliated Hospital, Sun Yat-Sen University 38
Not applicableStudy completedNCT04957160
What this trial is testing

Cabozantinib Post First-line Immuno-oncology Checkpoint Inhibitor Containing Combination

Who this might be right for
Advanced Renal Cell Carcinoma (aRCC)
Ipsen 281
Testing effectiveness (Phase 2)Study completedNCT00729482
What this trial is testing

RAD001 (Everolimus) Salvage Monotherapy in Advanced Gastric Cancer (AGC) Who Failed Standard First-line Treatment

Who this might be right for
Stomach Neoplasm
Asan Medical Center 54
Testing effectiveness (Phase 2)Ended earlyNCT01855724
What this trial is testing

Clinical Trial to Investigate the Efficacy of Treatment With Gemcitabine/Pazopanib in Patients With Biliary Tree Cancer

Who this might be right for
CholangiocarcinomaGallbladder CarcinomaBiliary Carcinoma
Hellenic Cooperative Oncology Group 29
Not applicableStudy completedNCT03519542
What this trial is testing

Epidemiological Study to Identify Prognosis and Predictive Biomarkers for Advanced or Metastatic Renal Cell Carcinoma

Who this might be right for
Metastatic Renal Cell Carcinoma
Spanish Oncology Genito-Urinary Group 62
Not applicableNot Yet RecruitingNCT07042282
What this trial is testing

Comparison of Initial Treatment for Carpal Tunnel Syndrome Related to Rheumatic Diseases: Corticosteroid Injection Versus Nighttime Splinting

Who this might be right for
Carpal Tunnel Syndrome (CTS)Rheumatic Diseases
Yun Qian 248
Testing effectiveness (Phase 2)Ended earlyNCT02173990
What this trial is testing

Aflibercept and Chemotherapy as First Line Treatment for Metastatic Colorectal Cancer Assessable With DCE-US (PULSAR).

Who this might be right for
Metastatic Colorectal Cancer
Centre Oscar Lambret 40
Testing effectiveness (Phase 2)Study completedNCT05877820
What this trial is testing

Evaluate Efficacy and Safety of Lenvatinib Combined With Tislelizumab in Patients With FHRCC

Who this might be right for
Fumarate Hydratase Deficient Renal Cell Carcinoma
RenJi Hospital 20
Not applicableUnknownNCT04858828
What this trial is testing

Investigation on Predictive Molecular Markers of Efficacy for Front-line Immunochemotherapy in Advanced NSCLC

Who this might be right for
Biomarkers
Zhou Chengzhi 200
Testing effectiveness (Phase 2)Study completedNCT02392507
What this trial is testing

Nab-Paclitaxel and Carboplatin Plus Necitumumab (LY3012211) in Participants With Stage IV Squamous NSCLC

Who this might be right for
Carcinoma, Non-Small Cell Lung Cancer (NSCLC)
Eli Lilly and Company 54
Large-scale testing (Phase 3)Not Yet RecruitingNCT05767892
What this trial is testing

YK-029A as First-Line Treatment Versus Platinum-Based Chemotherapy for Non-Small Cell Lung Cancer (NSCLC) With EGFR Exon 20 Insertion Mutations

Who this might be right for
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Suzhou Puhe Pharmaceutical Technology Co., LTD 350
Large-scale testing (Phase 3)Ended earlyNCT00047632
What this trial is testing

Safety and Efficacy of Interferon Gamma-1b Plus Chemotherapy for Ovarian and Peritoneal Cancer

Who this might be right for
Ovarian CarcinomaPeritoneal Carcinoma
InterMune 847
Early research (Phase 1)Study completedNCT02668393
What this trial is testing

Nintedanib and Weekly Docetaxel in Lung Adenocarcinoma

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 14
Testing effectiveness (Phase 2)Study completedNCT01161316
What this trial is testing

Safety and Efficacy Study of mFOLFOX-6 Plus Cetuximab for 8 Cycles Followed by mFOLFOX-6 Plus Cetuximab or Single Agent Cetuximab as Maintenance Therapy in Patients With Metastatic Colorectal Cancer and WT KRAS Tumours

Who this might be right for
Metastatic Colorectal Cancer
Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) 194
Post-approval studies (Phase 4)Study completedNCT00706706
What this trial is testing

Safety And Efficacy Study Of Sunitinib Malate As First-Line Systemic Therapy In Chinese Patients With Metastatic Renal Cell Carcinoma

Who this might be right for
Carcinoma, Renal Cell
Pfizer 105
Post-approval studies (Phase 4)Study completedNCT01498887
What this trial is testing

Efficacy of Fingolimod in de Novo Patients Versus Fingolimod in Patients Previously Treated With a First Line Disease Modifying Therapy

Who this might be right for
Relapsing Remitting Multiple Sclerosis
Novartis Pharmaceuticals 347
Next Page