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Results for “Intensive Chemotherapy Unfit”

20 trials

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Showing 20 of 20 results

Early research (Phase 1)Ended earlyNCT03395873
What this trial is testing

Avelumab With Decitabine as First Line for AML Treatment of Patients With AML, Who Are Unfit for Intensive Chemotherapy

Who this might be right for
Acute Myeloid Leukemia
Milton S. Hershey Medical Center 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT04284787
What this trial is testing

BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia Post Cytotoxic Therapy+1 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT04827719
What this trial is testing

BST-236 as a Single Agent in Adults With Relapsed or Refractory AML or HR-MDS

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid Leukemia
Groupe Francophone des Myelodysplasies 38
Not applicableUnknownNCT02698124
What this trial is testing

Decitabine for Chemotherapy Unfit Korean AML Patients in Real Practice

Who this might be right for
Acute Myeloid LeukemiaElderlyIntensive Chemotherapy Unfit
Ulsan University Hospital 136
Testing effectiveness (Phase 2)Study completedNCT01810705
What this trial is testing

GRASPA Treatment for Patients With Acute Myeloblastic Leukemia

Who this might be right for
Acute Myeloid Leukemia
ERYtech Pharma 123
Large-scale testing (Phase 3)Looking for participantsNCT06810791
What this trial is testing

HVA vs IA/DA or VA in the Treatment of ND HR-AML

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia With High Risk
Nanfang Hospital, Southern Medical University 876
Early research (Phase 1)Ended earlyNCT03552029
What this trial is testing

Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Daiichi Sankyo 10
Testing effectiveness (Phase 2)UnknownNCT04541277
What this trial is testing

Combined Inhibition of PD-1 and DNA Hypomethylating Agent +/- Chemotherapy in High-risk AML or Elderly Patients With AML Who Are Unfit for Intensive Chemotherapy

Who this might be right for
Acute Myeloid Leukemia, in Relapsed or RefractoryAcute Myeloid Leukemia, Elderly, UnfitAcute Myeloid Leukemia With Positive Minimal Residual Disease
Chinese PLA General Hospital 55
Early research (Phase 1)UnknownNCT00636922
What this trial is testing

Everolimus (RAD001) in Elderly Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Bayside Health 40
Testing effectiveness (Phase 2)Looking for participantsNCT07172204
What this trial is testing

Alternating Regimen of VA and Low-dose CHA in the Treatment of Unfit Newly Diagnosed AML

Who this might be right for
Intensive Chemotherapy UnfitNewly Diagnosed Acute Myeloid Leukemia (AML)Age ≥60
First Affiliated Hospital of Zhejiang University 25
Testing effectiveness (Phase 2)Ended earlyNCT04051996
What this trial is testing

GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia

Who this might be right for
ACUTE MYELOID LEUKEMIA
Yale University 1
Large-scale testing (Phase 3)Study completedNCT01237808
What this trial is testing

Study of Low-Dose Cytarabine and Etoposide With or Without All-Trans Retinoic Acid in Older Patients Not Eligible for Intensive Chemotherapy With Acute Myeloid Leukemia and NPM1 Mutation

Who this might be right for
Acute Myeloid Leukemia (AML)
University of Ulm 144
Testing effectiveness (Phase 2)Ended earlyNCT06150040
What this trial is testing

Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX]

Who this might be right for
Acute Myeloid Leukemia Refractory
Centre Leon Berard 1
Early research (Phase 1)Study completedNCT04038437
What this trial is testing

A Trial of CPX-351 Lower Intensity Therapy (LIT) Plus Venetoclax as First Line Treatment for Subjects With AML

Who this might be right for
Acute Myeloid Leukemia
Jazz Pharmaceuticals 35
Testing effectiveness (Phase 2)UnknownNCT04749355
What this trial is testing

Phase 2, Open-Label, Single Arm Study, With BST-236 in Adults With R/R AML or Higher-Risk MDS

Who this might be right for
AML, AdultMDSRelapse/Recurrence+1 more
BioSight Ltd. 40
Testing effectiveness (Phase 2)UnknownNCT05503355
What this trial is testing

A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML

Who this might be right for
AML, Adult
BioSight Ltd. 80
Testing effectiveness (Phase 2)UnknownNCT04824924
What this trial is testing

Venetoclax in Combination With Low-dose HHT, G-CSF, and AZA as First-line Treatment for Newly Diagnosed Elderly AML Patients Unfit for Intensive Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Shanghai Jiao Tong University School of Medicine 100
Testing effectiveness (Phase 2)WithdrawnNCT06770257
What this trial is testing

Daunorubicin, Cytarabine Liposomes Plus Venetoclax vs Azacitidine Plus Venetoclax in AML Patients Unfit for Intensive Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Institute of Hematology & Blood Diseases Hospital, China
Testing effectiveness (Phase 2)Active Not RecruitingNCT04763928
What this trial is testing

Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclax

Who this might be right for
Acute Myeloid Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 101
Testing effectiveness (Phase 2)Study completedNCT04266795
What this trial is testing

Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy

Who this might be right for
Acute Myeloid Leukemia (AML)
Takeda 164
60