Post-approval studies (Phase 4)Study completedNCT07395271What this trial is testingComparing Doses of Intrathecal DexmedetomidineWho this might be right forDexmedetomidine Bahria International Hospital 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06537297What this trial is testingIntrathecal Pemetrexed Combined With High-dose Furmonertinib and Beva for EGFR-m NSCLC With Leptomeningeal MetastasesWho this might be right forNon-small Cell Lung Cancer Hunan Province Tumor Hospital 30
Early research (Phase 1)Not Yet RecruitingNCT07702305What this trial is testingSafety and Efficacy of Intrathecal Sacituzumab Tirumotecan for Leptomeningeal Metastasis in EGFR-TKI-Resistant Non-Small Cell Lung CancerWho this might be right forEGFR-TKI-resistant Non-small Cell Lung Cancer With Leptomeningeal Metastasis Henan Cancer Hospital 15
Large-scale testing (Phase 3)Active Not RecruitingNCT05606614What this trial is testingA Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)Who this might be right forRett Syndrome Taysha Gene Therapies, Inc. 17
Early research (Phase 1)Active Not RecruitingNCT06069687What this trial is testingAdministration of MELPIDA to Determine the Safety and Efficacy for Patients With Spastic Paraplegia Type 50Who this might be right forSpastic Paraplegia Type 50 The Hospital for Sick Children 1
Not applicableNot Yet RecruitingNCT05977361What this trial is testingIntrathecal Catheter Placement Versus Resiting Epidural Catheter After Dural Puncture in Obstetric PatientsWho this might be right forAnalgesia, ObstetricalPost-Dural Puncture Headache Fondazione Policlinico Universitario Agostino Gemelli IRCCS 181
Not applicableLooking for participantsNCT06572241What this trial is testingQuality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal EpiduralWho this might be right forLabor Pain Samuel Lunenfeld Research Institute, Mount Sinai Hospital 182
Not applicableStudy completedNCT05560542What this trial is testingIntrathecal Dexamethasone and Atropine on Morphine Induced Post-operative Nausea and Vomiting on Caesarean SectionWho this might be right forMorphine Adverse Reaction Assiut University 150
Post-approval studies (Phase 4)Study completedNCT03451695What this trial is testingEffect of Intrathecal Morphine on Chronic Pain After Elective Caesarean SectionWho this might be right forChronic Pain Post-Procedural B.P. Koirala Institute of Health Sciences 290
Early research (Phase 1)Study completedNCT03824314What this trial is testingEffect of Adding Midazolam Versus Fentanyl to Intrathecal Levobupivacaine in Patients Undergoing Caesarean SectionWho this might be right forCesarean Section Complications Mohamed Abdelrady Mohamed 80
Not applicableStudy completedNCT06108895What this trial is testingIlioinguinal Iliohypogastric Nerve Block as Adjunct to Spinal Anesthesia for Cesarean SectionWho this might be right forCesarean SectionPost Operative Pain Tanta University 90
Testing effectiveness (Phase 2)Study completedNCT02619019What this trial is testingEffect of Spinal Dexamethasone During Transuretheral ProstatectomyWho this might be right forPostspinal Shivering Assiut University 90
Early research (Phase 1)Study completedNCT04205019What this trial is testingSafety Stem Cells in Spinal Cord InjuryWho this might be right forSpinal Cord Injuries Neuroplast 10
Early research (Phase 1)Study completedNCT00406016What this trial is testingAcute Safety, Tolerability, Feasibility and Pharmacokinetics of Intrath. Administered ATI355 in Patients With Acute SCIWho this might be right forAcute Spinal Cord Injury Novartis 52
Not applicableEnded earlyNCT02232477What this trial is testingExtension Study of Intrathecal Enzyme Replacement for Cognitive Decline in MPS IWho this might be right forMucopolysaccharidosis ICognitive Decline agnes chen 6
Post-approval studies (Phase 4)Enrolling By InvitationNCT07643493What this trial is testingCleaRRAflow: Isotonic Solution vs. TPA for IVH ClearanceWho this might be right forTissue Plasminogen ActivatorIntraventricular Brain Hemorrhage David Dornbos 80
Early research (Phase 1)Study completedNCT00854867What this trial is testingStudy to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.Who this might be right forSolid Tumour Neoplastic MeningitisBrain Metastases Mundipharma Research Limited 18
Testing effectiveness (Phase 2)Looking for participantsNCT06980948What this trial is testingSafety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)Who this might be right forChronic Neuropathic Pain Sangamo Therapeutics 27
Post-approval studies (Phase 4)Study completedNCT03932578What this trial is testingIntrathecal Atropine vs IV Metoclopramide for Nausea & Vomiting During CSWho this might be right forNauseaVomiting Mansoura University 60
Not applicableStudy completedNCT06837506What this trial is testingUltrasound Guided Rectus Sheath Block Versus Intrathecal Morphine for Postoperative Analgesia in Patients Undergoing Open Total Abdominal HysterectomyWho this might be right forUltrasoundRectus Sheath BlockIntrathecal Morphine+2 more Ain Shams University 80