Testing effectiveness (Phase 2)Study completedNCT00211757What this trial is testingDivalproex Sodium vs. Placebo in Childhood/Adolescent AutismWho this might be right forAutism Montefiore Medical Center 27
Post-approval studies (Phase 4)Study completedNCT00211796What this trial is testingDivalproex Sodium ER in Adult AutismWho this might be right forAutism Montefiore Medical Center 10
Not applicableStudy completedNCT00627250What this trial is testingUtility of Amantadine Hydrochloride in the Treatment of Post-traumatic IrritabilityWho this might be right forIrritable MoodAggressionTraumatic Brain Injury Wake Forest University Health Sciences 76
Not applicableEnrolling By InvitationNCT02914951What this trial is testingCognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual DisabilityWho this might be right forAutismIntellectual Disability Yale University 6
Post-approval studies (Phase 4)Looking for participantsNCT06871488What this trial is testingPredictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS StimulantsWho this might be right forADHD - Attention Deficit Disorder With HyperactivityIrritabilityAggression Childhood Milton S. Hershey Medical Center 136
Not applicableStudy completedNCT00779324What this trial is testingAmantadine for the Treatment of Traumatic Brain Injury Irritability and Aggression: A Multi-site StudyWho this might be right forBrain InjuryAggression Wake Forest University Health Sciences 168
Large-scale testing (Phase 3)Study completedNCT00198107What this trial is testingEvaluating the Effectiveness of Aripiprazole and D-Cycloserine to Treat Symptoms Associated With AutismWho this might be right forAutistic Disorder Indiana University 81
Not applicableActive Not RecruitingNCT04654260What this trial is testingBehavior Therapy for Irritability in AutismWho this might be right forAutism Spectrum DisorderIrritabilityDisruptive Behavior+4 more Yale University 65
Not applicableStudy completedNCT00468130What this trial is testingEfficacy of Aripiprazole Versus Placebo in the Reduction of Aggressive and Aberrant Behavior in Autistic ChildrenWho this might be right forAutism University of Medicine and Dentistry of New Jersey 13
Post-approval studies (Phase 4)Study completedNCT01821690What this trial is testingBuspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and AggressionWho this might be right forTraumatic Brain Injury Indiana University 81
Not applicableStudy completedNCT00621751What this trial is testingCarbamazepine for the Treatment of Chronic Post-Traumatic Brain Injury Irritability and AggressionWho this might be right forTraumatic Brain Injury Wake Forest University Health Sciences 70
Not applicableStudy completedNCT01965184What this trial is testingCognitive-Behavioral Therapy for Disruptive Behavior in Children and AdolescentsWho this might be right forDisruptive BehaviorAggressionAnger+2 more Yale University 101
Not applicableStudy completedNCT03697837What this trial is testingDigital Parent Training for Disruptive Behaviors in ChildrenWho this might be right forDisruptive BehaviorAggression ChildhoodAnger+2 more Yale University 16
Not applicableStudy completedNCT01631851What this trial is testingCognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum DisorderWho this might be right forAutismAutism Spectrum Disorder (ASDAsperger's Disorder+1 more Yale University 9
Testing effectiveness (Phase 2)Study completedNCT03095066What this trial is testingStudy to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Neurobehavioral Disinhibition Including Aggression, Agitation, and Irritability in Participants With Traumatic Brain InjuryWho this might be right forNeurobehavioral Disinhibition Otsuka Pharmaceutical Development & Commercialization, Inc. 168
Early research (Phase 1)Study completedNCT02552147What this trial is testingNicotinic Cholinergic Modulation as a Novel Treatment Strategy for Aggression Associated With AutismWho this might be right forAutism Spectrum DisorderAggressionIrritability Yale University 8
Not applicableLooking for participantsNCT06875986What this trial is testingREXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)Who this might be right forAlzheimer Disease Otsuka Pharmaceutical Co., Ltd. 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07328529What this trial is testingInhibition of Aggressive Behavior in Participants With Fragile X SyndromeWho this might be right forAggressive Behavior in Fragile X Syndome Azevan Pharmaceuticals 80
Not applicableStudy completedNCT00467753What this trial is testingOxcarbazepine Versus Placebo in Childhood AutismWho this might be right forAutism University of Medicine and Dentistry of New Jersey 5
Post-approval studies (Phase 4)Study completedNCT02078596What this trial is testingDepakote (Divalproex Sodium) for Children With Temper Dysregulation and Severe Mood SwingsWho this might be right forIrritable Aggression New York State Psychiatric Institute 15