Post-approval studies (Phase 4)Study completedNCT01743742What this trial is testingFirst-day High Dose Vitamin C, E in Severe Birth AsphyxiaWho this might be right forBirth Asphyxia Sir Takhtasinhji General Hospital 95
Early research (Phase 1)Study completedNCT02700854What this trial is testingHypoxic-Ischemic Encephalopathy Therapy Optimization in Neonates for Better Neuroprotection With Inhalative CO2Who this might be right forHypoxic-Ischaemic EncephalopathyPerinatal AsphyxiaHypocapnia Semmelweis University 10
Large-scale testing (Phase 3)Not Yet RecruitingNCT07652801What this trial is testingCOMPARISON OF OUTCOME OF HYPOXIC ISCHEMIC ENCEPHLOPATHY MANAGED WITH COMBINATION OF MAGNESIUM SULPHATE AND MELATONIN VERSUS MAGNESIUM SULPHATE ALONEWho this might be right forHIE - Hypoxic - Ischemic Encephalopathy University of Child Health Sciences and Children's Hospital, Lahore 80
Early research (Phase 1)Study completedNCT00719407What this trial is testingNeonatal Erythropoietin in Asphyxiated Term NewbornsWho this might be right forHypoxic-ischemic Encephalopathy University of California, San Francisco 24
Large-scale testing (Phase 3)Study completedNCT02700828What this trial is testingHydrocortisone Treatment In Systemic Low Blood Pressure During Hypothermia in Asphyxiated NewbornsWho this might be right forHypoxic-Ischemic EncephalopathyAsphyxia Semmelweis University 32
Not applicableLooking for participantsNCT07197918What this trial is testingIdentification of Brain Injury Using Portable MRIWho this might be right forCardiac Arrest (CA)Hypoxic-Ischemic Brain Injury Yale University 60
Not applicableEnded earlyNCT03246243What this trial is testingQuantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High RiskWho this might be right forHypoxic-Ischemic EncephalopathyHypoglycemiaNeonatal Abstinence Syndrome Boston Children's Hospital 16
Early research (Phase 1)WithdrawnNCT05295784What this trial is testingPK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic HypothermiaWho this might be right forAcute Kidney InjuryHypoxic-Ischemic EncephalopathyCaffeine University of Arkansas
Not applicableLooking for participantsNCT04445649What this trial is testingPrognostic Factors to Regain ConsciousnessWho this might be right forNeurologic DisorderDisorder of ConsciousnessTraumatic Brain Injury+2 more BDH-Klinik Hessisch Oldendorf 130
Not applicableEnrolling By InvitationNCT07770035What this trial is testingSchool-aged Outcomes Post Hypoxic Ischaemic EncephalopathyWho this might be right forHypoxic-Ischemic Encephalopathy University College Cork 196
Not applicableUnknownNCT02644265What this trial is testingCONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEGWho this might be right forAcute Brain InjuriesConsciousness Disorders Rigshospitalet, Denmark 100
Not applicableUnknownNCT05048550What this trial is testingBabies in Glasses; a Feasibility Study.Who this might be right forCerebral Visual ImpairmentRefractive and Accommodative DisordersHypoxic-Ischemic Encephalopathy+1 more Great Ormond Street Hospital for Children NHS Foundation Trust 55
Testing effectiveness (Phase 2)UnknownNCT01138176What this trial is testingWhole Body Cooling Using Phase Changing MaterialWho this might be right forHypoxic Ischemic Encephalopathy Robertson, Nicola, M.D. 35
Not applicableStudy completedNCT02349672What this trial is testingClinical Utility of Serum Biomarkers for the Management of Neonatal Hypoxic Ischemic Encephalopathy (Control Levels)Who this might be right forHypoxic Ischemic Encephalopathy University of Florida 39
Testing effectiveness (Phase 2)Looking for participantsNCT05851391What this trial is testingBuRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac ArrestWho this might be right forHypoxia-Ischemia, BrainHeart ArrestStatus Epilepticus+4 more University of California, San Francisco 30
Not applicableLooking for participantsNCT05767476What this trial is testingNeurodevelopmental Outcome in Newborn With Hypoxic-ischemic Encephalopathy Treated With Therapeutic HypothermiaWho this might be right forEncephalopathy, Hypoxic Ischemic Fondazione Policlinico Universitario Agostino Gemelli IRCCS 70
Not applicableUnknownNCT02578823What this trial is testingTargeted Temperature Management After In-Hospital Cardiac ArrestWho this might be right forHypoxic Ischemic Encephalopathy Asan Medical Center 60
Not applicableStudy completedNCT05379218What this trial is testingRIC in HIE: A Safety and Feasibility TrialWho this might be right forHypoxic-Ischemic Encephalopathy The Hospital for Sick Children 32
Not applicableLooking for participantsNCT07527104What this trial is testingAutologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial HemorrhageWho this might be right forCerebral Palsy Hypoxic-Ischemic Encephalopathy Intracranial Hemorrhage National Children's Hospital, Vietnam 60
Not applicableEnded earlyNCT01192776What this trial is testingOptimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)Who this might be right forInfant, NewbornHypoxia, BrainHypoxia-Ischemia, Brain+3 more NICHD Neonatal Research Network 364