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Results for “Isocitrate Dehydrogenase”

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Showing 13 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02677922
What this trial is testing

Assess the Safety and Efficacy of Two Combinations of Isocitrate Dehydrogenase (IDH) Mutant Targeted Therapies Plus Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) Harboring IDH Mutations Who Are Not Candidates to Receive Intensive Induction Chemotherapy

Who this might be right for
Leukemia, Myeloid, Acute
Celgene 130
Testing effectiveness (Phase 2)Looking for participantsNCT05588141
What this trial is testing

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

Who this might be right for
Brain TumorCancer
National Cancer Institute (NCI) 96
Not applicableLooking for participantsNCT06430424
What this trial is testing

Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Who this might be right for
Relapsed CancerGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
University Hospital, Bordeaux 40
Large-scale testing (Phase 3)Not Yet RecruitingNCT07712757
What this trial is testing

Safety and Efficacy Study of Safusidenib in Participants With Grade 2 IDH1-Mutant Glioma

Who this might be right for
Grade 2 Glioma (Astrocytoma or Oligodendroglioma) With an IDH1 MutationAstrocytoma IDH Mutant Grade 2Oligodendroglioma+2 more
Nuvation Bio Inc. 140
Testing effectiveness (Phase 2)Study completedNCT02496741
What this trial is testing

Metformin And Chloroquine in IDH1/2-mutated Solid Tumors

Who this might be right for
GliomaCholangiocarcinomaChondrosarcoma
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04677049
What this trial is testing

Study of Niacin in Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
AHS Cancer Control Alberta 59
Testing effectiveness (Phase 2)WithdrawnNCT04737174
What this trial is testing

ES-481 for Uncontrolled Glioma-Associated Epilepsy and Assessment for Potential Anti-Tumorigenic Effect in Patients With Isocitrate Dehydrogenase 1 (IDH1) Mutant Tumors

Who this might be right for
Epilepsy; Seizure
ES Therapeutics Australia Pty Ltd
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07386002
What this trial is testing

The GLIOMAX Study: MT027 Allogeneic CAR-T for Recurrent Glioma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
T-MAXIMUM Pharmaceutical Inc 40
Very early researchLooking for participantsNCT06552260
What this trial is testing

A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

Who this might be right for
GlioblastomaRecurrent GlioblastomaBrain Tumor
Ugonma Chukwueke 27
Early research (Phase 1)Active Not RecruitingNCT04603001
What this trial is testing

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+1 more
Eli Lilly and Company 260
Large-scale testing (Phase 3)Study completedNCT02577406
What this trial is testing

An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutation

Who this might be right for
Leukemia, MyeloidIsocitrate Dehydrogenase
Celgene 319
Early research (Phase 1)Ended earlyNCT04782609
What this trial is testing

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

Who this might be right for
Recurrent Glioblastoma Multiforme (GBM)Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype AstrocytomaGrade 3 or 4 Astrocytoma+1 more
Samus Therapeutics, Inc. 7
Very early researchEnrolling By InvitationNCT07520214
What this trial is testing

Clinical Study on the Safety and Immunogenicity of Specific Cancer Vaccines in Preventing Recurrence of Glioblastoma

Who this might be right for
Glioblastoma IDH (Isocitrate Dehydrogenase) WildtypeGlioblastom WHO Grade 4
Beijing Neurosurgical Institute 9