Very early researchStudy completedNCT05851378What this trial is testingHyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant GliomaWho this might be right forAdult Gliomas, Mixed Robert Bok, MD, PhD 13
Large-scale testing (Phase 3)Looking for participantsNCT03970447What this trial is testingA Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaWho this might be right forGlioblastoma Global Coalition for Adaptive Research 2,250
Early research (Phase 1)Ended earlyNCT04764474What this trial is testingHMPL-306 in Advanced Hematological Malignancies With mIDHWho this might be right forIsocitrate Dehydrogenase Gene Mutation Hutchmed 46
Early research (Phase 1)Not Yet RecruitingNCT07629089What this trial is testingVorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 MutationsWho this might be right forBrain Cancer Megan Mantica 24
Testing effectiveness (Phase 2)Study completedNCT02428855What this trial is testingPhase II Trial of Dasatinib in Patients With Isocitrate Dehydrogenase (IDH)-Mutant Advanced Intrahepatic CholangiocarcinomaWho this might be right forCholangiocarcinoma Massachusetts General Hospital 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07620548What this trial is testingLaser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent GlioblastomasWho this might be right forGlioblastomaGlioblastoma, IDH-wildtypeGlioblastoma IDH (Isocitrate Dehydrogenase) Wildtype Washington University School of Medicine 99
Testing effectiveness (Phase 2)Looking for participantsNCT07416188What this trial is testingNovel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent GlioblastomaWho this might be right forRecurrent GlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeRelapsed Cancer+12 more National Institute of Neurological Disorders and Stroke (NINDS) 40
Large-scale testing (Phase 3)Looking for participantsNCT05303519What this trial is testingSIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)Who this might be right forGliomaAstrocytoma, Grade IVIDH1-mutant Glioma+5 more Nuvation Bio Inc. 365
Testing effectiveness (Phase 2)WithdrawnNCT02977689What this trial is testingTrial of IDH305 in IDH1 Mutant Grade II or III GliomaWho this might be right forGlioma NYU Langone Health
Not applicableActive Not RecruitingNCT05969691What this trial is testingRadiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in GliomasWho this might be right forGlioma, MalignantComputer-Assisted Mingge LLC 18
Testing effectiveness (Phase 2)Looking for participantsNCT06717958What this trial is testingProspective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) MutationWho this might be right forAMLMDS Technische Universität Dresden 76
Large-scale testing (Phase 3)Active Not RecruitingNCT05987358What this trial is testingA Clinical Study of TQB3454 Tablets in the Treatment of Advanced Biliary Carcinoma.Who this might be right forBiliary Carcinoma Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 165
Not applicableStudy completedNCT05375318What this trial is testingBIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological LevelsWho this might be right forAstrocytoma, Grade IVGlioblastomaGlioblastoma Multiforme+5 more Juan M Garcia-Gomez 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07604285What this trial is testingSafety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated GlioblastomaWho this might be right forGlioblastoma Myosin Therapeutics Inc. 36
Not applicableLooking for participantsNCT07668869What this trial is testingTTFields Plus FET-PET-Guided Stereotactic Radiosurgery Versus TTFields Alone for Recurrent Glioblastoma (Tarrget 2.0)Who this might be right forGlioblastomaGlioblastoma IDH (Isocitrate Dehydrogenase) WildtypeGlioblastoma Multiforme, Adult Prof. Franciszek Lukaszczyk Memorial Oncology Center 92
Testing effectiveness (Phase 2)Study completedNCT02968940What this trial is testingAvelumab With Hypofractionated Radiation Therapy in Adults With Isocitrate Dehydrogenase (IDH) Mutant GlioblastomaWho this might be right forGlioblastoma NYU Langone Health 6
Not applicableLooking for participantsNCT03684109What this trial is testingNon-invasive Glioma Characterization Through Molecular ImagingWho this might be right forGliomaBrain TumorPrimary Brain Tumor+2 more University of Miami 30
Testing effectiveness (Phase 2)Looking for participantsNCT05864534What this trial is testingPhase 2a Immune Modulation With Ultrasound for Newly Diagnosed GlioblastomaWho this might be right forNewly Diagnosed GlioblastomaGlioblastoma, Isocitric Dehydrogenase (IDH)-WildtypeGliosarcoma+1 more Northwestern University 25
Testing effectiveness (Phase 2)Ended earlyNCT05267106What this trial is testingStudy to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 AlterationsWho this might be right forGlioblastomaAdult-type Diffuse Gliomas Incyte Corporation 83
Not applicableUnknownNCT03102112What this trial is testingNoninvasively Predicting Gene Status of GliomaWho this might be right forGlioma of Brain Tang-Du Hospital 50