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Results for “Ivonescimab”

92 trials

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Showing 20 of 92 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07158489
What this trial is testing

Overcoming Resistance to Immunotherapy Combining Gemcitabine With Ivonescimab in Advanced NSCLC

Who this might be right for
NSCLCNSCLC (Advanced Non-small Cell Lung Cancer)
Swiss Cancer Institute 47
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06993025
What this trial is testing

Ivonescimab in Combination With Liposomal Irinotecan and 5-FU/LV in Potentially Resectable Biliary Tract Malignancies

Who this might be right for
Biliary Tract Cancer
Tianjin Medical University Cancer Institute and Hospital 30
Early research (Phase 1)Not Yet RecruitingNCT07363408
What this trial is testing

Ivonescimab and ADG126, Alone, and in Combination With Leucovorin and Fluorouracil or FOLFIRI Regimen for the Treatment of Microsatellite Stable Advanced/Metastatic Colorectal Cancer

Who this might be right for
Advanced Microsatellite Stable Colorectal CarcinomaMetastatic Microsatellite Stable Colorectal CarcinomaStage III Colorectal Cancer AJCC v8+1 more
City of Hope Medical Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT07516925
What this trial is testing

Ivonescimab in People With Leiomyosarcoma

Who this might be right for
Leiomyosarcoma
Memorial Sloan Kettering Cancer Center 20
Testing effectiveness (Phase 2)Looking for participantsNCT06805617
What this trial is testing

Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers

Who this might be right for
Salivary Gland CancerAdvanced Salivary Gland CarcinomaMetastatic Salivary Gland Cancer+1 more
Glenn J. Hanna 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07244965
What this trial is testing

Neoadjuvant Ivonescimab Plus Chemotherapy Followed by Concurrent Chemoradiotherapy in High-Risk Locally Advanced Cervical Cancer

Who this might be right for
LOCALLY ADVANCED CERVICAL CANCERS
Women's Hospital School Of Medicine Zhejiang University 42
Large-scale testing (Phase 3)Looking for participantsNCT07228832
What this trial is testing

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Summit Therapeutics 600
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07234877
What this trial is testing

Phase II Study Evaluating Upfront SRT to All Brain Metastases Followed by Ivonescimab Plus Chemotherapy Versus Upfront Ivonescimab Plus Chemotherapy in Patients With Asymptomatic Active Brain Metastases From NSCLC

Who this might be right for
Non Small Cell Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC 158
Testing effectiveness (Phase 2)Looking for participantsNCT07385001
What this trial is testing

A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC

Who this might be right for
Esophageal Squamous Cell CarcinomaIvonescimabNeoadjuvant
Tang-Du Hospital 45
Testing effectiveness (Phase 2)Looking for participantsNCT07130240
What this trial is testing

Ivonescimab Combined With Paclitaxel and Cisplatin as Neoadjuvant Therapy Followed by Type A Hysterectomy in Stage IB2 and IIA1 Cervical Cancer

Who this might be right for
Cervical Cancers
Obstetrics & Gynecology Hospital of Fudan University 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07472478
What this trial is testing

Phase II Neoadjuvant Study of Garsorasib Followed by Ivonescimab Plus Chemotherapy in Resectable Stage IIA-IIIB KRAS G12C-Mutant NSCLC (GIVEN Study)

Who this might be right for
Lung Cancer (NSCLC)KRAS G12C Lung Cancer
Guangdong Provincial People's Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT07094685
What this trial is testing

Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaStage II Head and Neck Cutaneous Squamous Cell Carcinoma+2 more
University of Michigan Rogel Cancer Center 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06620796
What this trial is testing

A Phase II Study of Ivonescimab Combined with Cadonilimab and Chemotherapy in Extensive-stage Small Cell Lung Cancer

Who this might be right for
SCLC, Extensive Stage
Shanghai Pulmonary Hospital, Shanghai, China 70
Not applicableEnrolling By InvitationNCT06936488
What this trial is testing

A Prospective, Single Arm, Open Label, Phase II Clinical Study on the Efficacy and Safety of Ivonescimab (AK112) Combined With TAS-102 in the Treatment of Refractory MSS/pMMR Advanced Colorectal Cancer

Who this might be right for
MSS/pMMR Type Metastatic Colorectal Adenocarcinoma Patients
Huai'an First People's Hospital 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07021950
What this trial is testing

AK112 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI as Second-line Treatment of MSS/pMMR Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerIvonescimab
Sun Yat-sen University 130
Testing effectiveness (Phase 2)Looking for participantsNCT07535437
What this trial is testing

Ivonescimab in Combination With Dato-DXd or Osimertinib in People With Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center 66
Testing effectiveness (Phase 2)Looking for participantsNCT06951646
What this trial is testing

CtDNA-MRD Guided Escalation of Ivonescimab and Docetaxel in Advanced NSCLC With Long-Term Responses to First-line Immunotherapy (CR1STAL-Adaptive)

Who this might be right for
Non Small Cell Lung CancerImmune Checkpoint Inhibitors (ICIs)
Second Xiangya Hospital of Central South University 70
Testing effectiveness (Phase 2)Looking for participantsNCT06491472
What this trial is testing

Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 36
Testing effectiveness (Phase 2)Looking for participantsNCT06769971
What this trial is testing

Phase II Study of Ivonescimab and Cadonilimab in Combination with Chemotherapy in Patients with ES-SCLC

Who this might be right for
Small Cell Lung Cancer
Sichuan University 80
Testing effectiveness (Phase 2)Looking for participantsNCT06959550
What this trial is testing

Phase II Study of Anti-PD-1/VEGF Bispecific Antibody Ivonescimab in Patients With Previously Treated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
M.D. Anderson Cancer Center 90
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