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Results for “Ivosidenib”

55 trials

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Showing 20 of 55 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06081829
What this trial is testing

Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Who this might be right for
Cholangiocarcinoma Non-resectableCholangiocarcinoma Metastatic
Servier 12
Early research (Phase 1)Study completedNCT04176393
What this trial is testing

A China Bridging Study of Ivosidenib in r/r AML Subjects With an IDH1 Mutation

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia
CStone Pharmaceuticals 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06593548
What this trial is testing

Lvosidenib (AK112) Combined With CapeOX and Radiotherapy in Patients With Unresectable Metastatic MSS-type Colorectal Cancer

Who this might be right for
CRCMSSMetastatic Cancer
Fudan University 36
Early research (Phase 1)Study completedNCT02831972
What this trial is testing

Drug-Drug Interaction Study of AG120 in Healthy Subjects

Who this might be right for
Healthy
Agios Pharmaceuticals, Inc. 22
Not applicableStudy completedNCT06181734
What this trial is testing

Ivosidenib (TIBSOVO®) Combined With Azacitidine According to Current SmPC

Who this might be right for
Acute Myeloid Leukemia (AML)
iOMEDICO AG 8
Testing effectiveness (Phase 2)Active Not RecruitingNCT05030441
What this trial is testing

Ivosidenib for Patients With Clonal Cytopenia of Undetermined Significance and Mutations in IDH1

Who this might be right for
Clonal Cytopenia of Undetermined Significance
Washington University School of Medicine 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03173248
What this trial is testing

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia (AML)Untreated AMLAML Arising From Myelodysplastic Syndrome (MDS)+1 more
Institut de Recherches Internationales Servier 146
Testing effectiveness (Phase 2)Looking for participantsNCT07007949
What this trial is testing

A New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIvosidenib
The First Affiliated Hospital of Soochow University 42
Testing effectiveness (Phase 2)Looking for participantsNCT06717958
What this trial is testing

Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation

Who this might be right for
AMLMDS
Technische Universität Dresden 76
Large-scale testing (Phase 3)Active Not RecruitingNCT03839771
What this trial is testing

Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland 968
Early research (Phase 1)Looking for participantsNCT02074839
What this trial is testing

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia (AML)Untreated AMLOther IDH1-mutated Positive Hematologic Malignancies+1 more
Institut de Recherches Internationales Servier 291
Early research (Phase 1)Active Not RecruitingNCT02632708
What this trial is testing

Safety Study of AG-120 or AG-221 in Combination With Induction and Consolidation Therapy in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) With an IDH1 and/or IDH2 Mutation

Who this might be right for
Newly Diagnosed Acute Myeloid Leukemia (AML)Untreated AMLAML Arising From Myelodysplastic Syndrome (MDS)+2 more
Institut de Recherches Internationales Servier 153
Testing effectiveness (Phase 2)Looking for participantsNCT07282262
What this trial is testing

An Exploratory Study on the Use of Ivosidenib for the Precise Treatment of Advanced Biliary Tract Malignancies With IDH1 Mutations in the Later Line of Therapy.

Who this might be right for
Biliary Tract Cancer
Peking Union Medical College Hospital 300
Testing effectiveness (Phase 2)Study completedNCT04056910
What this trial is testing

Ivosidenib (AG-120) With Nivolumab in IDH1 Mutant Tumors

Who this might be right for
Advanced Solid TumorIDH1 MutationGlioma
Jason J. Luke, MD 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07507760
What this trial is testing

Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients

Who this might be right for
Acute Myeloid Leukemia With Gene Mutations
PETHEMA Foundation 50
Early research (Phase 1)Looking for participantsNCT05010772
What this trial is testing

Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission

Who this might be right for
Acute Myeloid Leukemia
M.D. Anderson Cancer Center 125
Not applicableLooking for participantsNCT06607302
What this trial is testing

Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study

Who this might be right for
Cholangiocarcinoma
iOMEDICO AG 100
Early research (Phase 1)Active Not RecruitingNCT05209074
What this trial is testing

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Ductal AdenocarcinomaResectable Pancreatic Cancer
Case Comprehensive Cancer Center 16
Early research (Phase 1)Study completedNCT03282513
What this trial is testing

AG-120 (Ivosidenib) in Subjects With Mild or Moderate Hepatic Impairment or Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Agios Pharmaceuticals, Inc. 33
Early research (Phase 1)Looking for participantsNCT06291987
What this trial is testing

Ivosidenib and Ruxolitinib in Patients With Advanced Myeloproliferative Neoplasms (MPNs) That Have an IDH1 Gene Mutation

Who this might be right for
Myeloproliferative Neoplasms
University of Chicago 18
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