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Results for “Janus Kinase Inhibitors”

188 trials

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Showing 20 of 188 results

Large-scale testing (Phase 3)Not Yet RecruitingNCT07357727
What this trial is testing

Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Who this might be right for
Primary Myelofibrosis (PMF)Post-polycythemia Vera Myelofibrosis (PPV-MF)Post-essential Thrombocythemia Myelofibrosis (PET-MF)
Novartis Pharmaceuticals 460
Large-scale testing (Phase 3)Study completedNCT01458574
What this trial is testing

Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 593
Early research (Phase 1)Study completedNCT05014360
What this trial is testing

JNJ-64251330 in Participants With Familial Adenomatous Polyposis

Who this might be right for
Adenomatous Polyposis Coli
Janssen Research & Development, LLC 42
Large-scale testing (Phase 3)Study completedNCT06758947
What this trial is testing

Use of Selective JAK Inhibitor in ILD and Skin Tightness of Systemic Sclerosis Versus MMF

Who this might be right for
Interstitial Lung Disease Due to Systemic Disease (Disorder)
Assiut University 60
Testing effectiveness (Phase 2)Study completedNCT05374785
What this trial is testing

Efficacy and Safety Study Comparing CPL409116 to Placebo in Participants With Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Celon Pharma SA 106
Early research (Phase 1)Ended earlyNCT01929941
What this trial is testing

An Open-Label Study of a Novel JAK-inhibitor, INCB047986, Given in Patients With Advanced Malignancies

Who this might be right for
Solid TumorHodgkin's LymphomaNHL (Non-Hodgkin Lymphoma)+5 more
Incyte Corporation 5
Large-scale testing (Phase 3)Active Not RecruitingNCT04006457
What this trial is testing

Long-Term PF-06651600 for the Treatment of Alopecia Areata

Who this might be right for
Alopecia Areata
Pfizer 1,052
Testing effectiveness (Phase 2)Looking for participantsNCT04370301
What this trial is testing

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Who this might be right for
Primary MyelofibrosisSecondary Myelofibrosis
Fred Hutchinson Cancer Center 20
Large-scale testing (Phase 3)Study completedNCT01976364
What this trial is testing

Open-Label Extension Study Of Tofacitinib In Psoriatic Arthritis

Who this might be right for
Arthritis, Psoriatic
Pfizer 686
Not applicableWithdrawnNCT05177471
What this trial is testing

Efficacy and Safety of JAK Inhibitors in Systemic Sclerosis-associated Interstitial Lung Disease

Who this might be right for
Systemic SclerosisInterstitial Lung Disease
Central Hospital, Nancy, France
Testing effectiveness (Phase 2)Looking for participantsNCT06158113
What this trial is testing

Efficacy and Safety of Baricitinib in Oral Lichen Planus: a Proof-of-Concept Study

Who this might be right for
Lichen Planus, OralLichen Planus, MucosalOral Lichen Planus
University of North Carolina, Chapel Hill 10
Testing effectiveness (Phase 2)Study completedNCT00147498
What this trial is testing

Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 Weeks

Who this might be right for
Rheumatoid Arthritis
Pfizer 264
Testing effectiveness (Phase 2)Active Not RecruitingNCT02723994
What this trial is testing

Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Incyte Corporation 171
Large-scale testing (Phase 3)Ended earlyNCT03920254
What this trial is testing

TD-1473 Long-Term Safety (LTS) Ulcerative Colitis (UC) Study

Who this might be right for
Ulcerative Colitis (UC)
Theravance Biopharma 46
Testing effectiveness (Phase 2)Study completedNCT03450330
What this trial is testing

Assessing an Oral Janus Kinase Inhibitor, AZD4205, in Combination With Osimertinib in Patients Who Have Advanced Non-small Cell Lung Cancer

Who this might be right for
Nonsmall Cell Lung Cancer
Dizal Pharmaceuticals 10
Large-scale testing (Phase 3)Study completedNCT04134728
What this trial is testing

Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 550
Post-approval studies (Phase 4)Study completedNCT03800979
What this trial is testing

Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia Areata

Who this might be right for
Alopecia Areata
Institute of Dermatology, Thailand 19
Not applicableUnknownNCT05120362
What this trial is testing

Evaluate JAK Inhibitor Cream in EGFR-inhibitor-induced Skin Rash

Who this might be right for
Acneiform Eruptions
Shanghai East Hospital 12
Testing effectiveness (Phase 2)Looking for participantsNCT06715982
What this trial is testing

JAK Inhibitors for Solid Malignant Tumor Patients With Immune Checkpoint Inhibitors-related Dermatitis: A Open-lable, Single Arm, Phase IIa Trial

Who this might be right for
Immune Checkpoint Inhibitors (ICI)-Related Dermatitis
Shixiu Wu 35
Early research (Phase 1)Study completedNCT04004663
What this trial is testing

Bioavailability Study of PF-06651600 Formulations in Healthy Participants

Who this might be right for
Healthy Volunteers
Pfizer 12
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