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Results for “Janus Kinase Inhibitors”

209 trials

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Showing 20 of 209 results

Not applicableStudy completedNCT04071405
What this trial is testing

Korea Post-marketing Surveillance for Xeljanz (Registered) in Ulcerative Colitis Patients

Who this might be right for
Ulcerative Colitis
Pfizer 110
Large-scale testing (Phase 3)Ended earlyNCT04477993
What this trial is testing

Ruxolitinib for Acute Respiratory Disorder Syndrome Due to COVID-19

Who this might be right for
Severe Acute Respiratory Syndrome Coronavirus 2SARS-CoV2
Vanderson Geraldo Rocha 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07682792
What this trial is testing

Golidocitinib in Patients With Mycosis Fungoides/Sézary Syndrome and T-Cell Large Granular Lymphocytic Leukemia

Who this might be right for
Mycosis Fungoides/Sezary SyndromeT-cell Large Granular Lymphocytic Leukemia
Washington University School of Medicine 24
Large-scale testing (Phase 3)Study completedNCT03745651
What this trial is testing

TRuE AD2 - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Incyte Corporation 618
Post-approval studies (Phase 4)Enrolling By InvitationNCT06660329
What this trial is testing

Efficacy and Safety of Tofacitinib in Refractory Blau Syndrome

Who this might be right for
Blau Syndrome
Peking Union Medical College Hospital 30
Large-scale testing (Phase 3)Study completedNCT04134728
What this trial is testing

Efficacy and Safety of GSK3196165 (Otilimab) Versus Placebo and Sarilumab in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Biological Disease-modifying Antirheumatic Drug (DMARDs) and/or Janus Kinase (JAK) Inhibitors

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 550
Not applicableActive Not RecruitingNCT05387980
What this trial is testing

Learn About the Study Medicine (CIBINQO) in People With Atopic Dermatitis.

Who this might be right for
Atopic Dermatitis
Pfizer 1,128
Testing effectiveness (Phase 2)Study completedNCT02997280
What this trial is testing

Ruxolitinib for Steroid-refractory GVHD

Who this might be right for
Graft Vs Host Disease
St. Petersburg State Pavlov Medical University 75
Testing effectiveness (Phase 2)Study completedNCT00147498
What this trial is testing

Three Dose Levels of CP-690,550 Monotherapy Versus Placebo, Administered Orally Twice Daily (BID) for 6 Weeks

Who this might be right for
Rheumatoid Arthritis
Pfizer 264
Testing effectiveness (Phase 2)Study completedNCT02723994
What this trial is testing

Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Incyte Corporation 171
Early research (Phase 1)Ended earlyNCT03320642
What this trial is testing

GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Who this might be right for
Hematologic Malignancies
Incyte Corporation 84
Early research (Phase 1)Study completedNCT02535689
What this trial is testing

Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 34
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07750574
What this trial is testing

Flonoltinib Maleate Oral Regimens in Patients With Myelofibrosis

Who this might be right for
MyelofibrosisMyelofibrosis Due to and Following Polycythemia VeraMyelofibrosis Transformation in Essential Thrombocythemia+9 more
Chengdu Zenitar Biomedical Technology Co., Ltd 105
Large-scale testing (Phase 3)Looking for participantsNCT06615050
What this trial is testing

Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Who this might be right for
Graft-versus-host Disease (GVHD)
Incyte Corporation 572
Testing effectiveness (Phase 2)UnknownNCT06244862
What this trial is testing

JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit

Who this might be right for
Hemophagocytic Syndromes
Assistance Publique - Hôpitaux de Paris 42
Large-scale testing (Phase 3)Study completedNCT01458574
What this trial is testing

Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Pfizer 593
Large-scale testing (Phase 3)Ended earlyNCT03584516
What this trial is testing

GRAVITAS-309: Itacitinib and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

Who this might be right for
Chronic Graft-versus-host Disease
Incyte Corporation 155
Large-scale testing (Phase 3)UnknownNCT05451615
What this trial is testing

Efficacy and Safety of Abatacept Combined With JAK Inhibitor for Refractory Rheumatoid Arthritis

Who this might be right for
AbataceptTreatment ComplianceRheumatoid Arthritis
Zhejiang Provincial People's Hospital 90
Testing effectiveness (Phase 2)UnknownNCT04640532
What this trial is testing

KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF

Who this might be right for
MyelofibrosisPost-PV MFPost-ET Myelofibrosis+1 more
Kartos Therapeutics, Inc. 116
Large-scale testing (Phase 3)Active Not RecruitingNCT04717414
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Subjects With Myeloproliferative Neoplasm-Associated Myelofibrosis on Concomitant JAK2 Inhibitor Therapy and Who Require Red Blood Cell Transfusions

Who this might be right for
Myeloproliferative DisordersMyelofibrosisPrimary Myelofibrosis+2 more
Celgene 313
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