Early research (Phase 1)Active Not RecruitingNCT04737460What this trial is testingStudy for the Treatment for CLN7 DiseaseWho this might be right forCLN7 Benjamin Greenberg 4
Not applicableLooking for participantsNCT05007990What this trial is testingCaregiving Networks Across Disease Context and the Life CourseWho this might be right forInherited Metabolic DisordersUndiagnosed DiseasesBatten's Disease+2 more National Human Genome Research Institute (NHGRI) 2,800
Not applicableActive Not RecruitingNCT04476862What this trial is testingCerliponase Alfa Observational Study in the USWho this might be right forLate-Infantile Neuronal Ceroid Lipofuscinosis Type 2 BioMarin Pharmaceutical 35
Not applicableLooking for participantsNCT01873924What this trial is testingClinical and Neuropsychological Investigations in Batten DiseaseWho this might be right forNeuronal Ceroid LipofuscinosisNeuronal Ceroid Lipofuscinosis CLN1Neuronal Ceroid Lipofuscinosis CLN2+7 more University of Rochester 500
Not applicableUnknownNCT04461561What this trial is testingUsing NPT to Evaluate Providing PPC as ELNEC-PPC WBT for NursesWho this might be right forCancerCardiac AnomalyCystic Fibrosis+4 more Altoosi University College 172
Not applicableLooking for participantsNCT04613089What this trial is testingNatural History and Longitudinal Clinical Assessments in NCL / Batten Disease, the International DEM-CHILD DatabaseWho this might be right forNeuronal Ceroid LipofuscinosisBatten DiseaseCLN1 Disease+12 more Universitätsklinikum Hamburg-Eppendorf 500
Not applicableEnded earlyNCT04974307What this trial is testingOptic-to-Audio Device in a Pediatric Cohort With CLN3-related Conditions or Low VisionWho this might be right forCLN3-related DisordersNon-CLN3 Related Low Vision Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 11
Large-scale testing (Phase 3)Not Yet RecruitingNCT04637282What this trial is testingSafety, Tolerability, and Efficacy of PLX-200 in Patients With CLN3Who this might be right forJuvenile Neuronal Ceroid Lipofuscinosis Polaryx Therapeutics, Inc. 39
Not applicableLooking for participantsNCT02435940What this trial is testingInherited Retinal Degenerative Disease RegistryWho this might be right forEye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more Foundation Fighting Blindness 20,000
Not applicableLooking for participantsNCT03307304What this trial is testingInvestigations of Juvenile Neuronal Ceroid LipofuscinosisWho this might be right forJuvenile Neuronal Ceroid Lipofuscinosis (CLN3)Batten Disease Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 300
Not applicableEnded earlyNCT04644549What this trial is testingNatural History Study of Batten DiseaseWho this might be right forBatten DiseaseNeuronal Ceroid Lipofuscinosis CLN6Neuronal Ceroid Lipofuscinosis CLN3 Emily de los Reyes 10
Testing effectiveness (Phase 2)Study completedNCT01399047What this trial is testingCellcept for Treatment of Juvenile Neuronal Ceroid LipofuscinosisWho this might be right forJuvenile Neuronal Ceroid Lipofuscinosis University of Rochester 19
Not applicableStudy completedNCT04808297What this trial is testingTrehalose in Subjects With Neuronal Ceroid LipofuscinosesWho this might be right forNeuronal Ceroid-Lipofuscinoses IRCCS Fondazione Stella Maris 8
Testing effectiveness (Phase 2)Study completedNCT05174039What this trial is testingAn Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of Subjects With Batten Ceroid Lipofuscinosis, Neuronal 3 (CLN3) DiseaseWho this might be right forBatten Disease Beyond Batten Disease Foundation 6
Not applicableStudy completedNCT01966757What this trial is testingNeuronal Ceroid Lipofuscinosis and Associated Sleep AbnormalitiesWho this might be right forNeuronal Ceroid LipofuscinosisBatten's Disease Nationwide Children's Hospital 57
Early research (Phase 1)WithdrawnNCT01238315What this trial is testingSafety and Efficacy Study of HuCNS-SC in Subjects With Neuronal Ceroid LipofuscinosisWho this might be right forNeuronal Ceroid Lipofuscinosis StemCells, Inc.
Not applicableStudy completedNCT05642221What this trial is testingFunctional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical ControlsWho this might be right forJuvenile Neuronal Ceroid LipofuscinosisSmith-Lemli-Opitz SyndromeCreatine Transporter Deficiency+1 more Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 73
Not applicableActive Not RecruitingNCT03285425What this trial is testingNatural History of Neuronal Ceroid Lipofuscinosis, Batten's CLN6 DiseaeWho this might be right forBatten DiseaseCLN6 Emily de los Reyes 30
Not applicableLooking for participantsNCT01793168What this trial is testingRare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordWho this might be right forRare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more Sanford Health 20,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT03770572What this trial is testingGene Therapy for Children With CLN3 Batten DiseaseWho this might be right forCLN3Batten Disease Alcyone Therapeutics, Inc 7