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Results for “KRAS G12D Mutations”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT07805954
What this trial is testing

Study of Zoldonrasib (RMC-9805) Plus Daraxonrasib (RMC-6236) Versus Gemcitabine and Nab-Paclitaxel as First-Line Treatment in Metastatic KRAS G12D-Mutated Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic CancerPancreatic Cancer MetastaticPDAC+5 more
Revolution Medicines, Inc. 400
Testing effectiveness (Phase 2)Looking for participantsNCT07629960
What this trial is testing

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more
Blueprint Medicines Corporation 265
Early research (Phase 1)Looking for participantsNCT07094204
What this trial is testing

Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Who this might be right for
Solid TumorNon-Small-Cell Lung CancerPancreatic Ductal Adenocarcinoma+1 more
Astellas Pharma Inc 364
Large-scale testing (Phase 3)Looking for participantsNCT07621718
What this trial is testing

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

Who this might be right for
Pancreatic CancerPancreatic Cancer MetastaticPDAC+5 more
Revolution Medicines, Inc. 670
Early research (Phase 1)Looking for participantsNCT07535112
What this trial is testing

Learn More About How Safe BAY 3771249 is and How Well it Works in People With Advanced or Metastatic Colorectal Cancer That Has a KRAS G12D Mutation

Who this might be right for
Advanced/Metastatic Colorectal Adenocarcinoma
Bayer 130
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06949761
What this trial is testing

A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of QLC1101 in Combination With Other Therapies in the Treatment of Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

Who this might be right for
Solid Tumor
Qilu Pharmaceutical Co., Ltd. 240
Large-scale testing (Phase 3)Looking for participantsNCT07522073
What this trial is testing

Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

Who this might be right for
Solid Tumors
Incyte Corporation 588
Early research (Phase 1)Ended earlyNCT05737706
What this trial is testing

Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

Who this might be right for
Solid TumorAdvanced Solid TumorNon-small Cell Lung Cancer+2 more
Mirati Therapeutics Inc. 63
Testing effectiveness (Phase 2)Looking for participantsNCT06445062
What this trial is testing

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Who this might be right for
Colorectal CancerCRCPancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc. 1,130
Early research (Phase 1)Looking for participantsNCT07207707
What this trial is testing

Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

Who this might be right for
Solid Tumor Malignancies
Kumquat Biosciences Inc. 78
Early research (Phase 1)Active Not RecruitingNCT05533463
What this trial is testing

Phase I Study of HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Who this might be right for
Advanced KRAS G12D Mutant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd. 102
Early research (Phase 1)Looking for participantsNCT06962254
What this trial is testing

Imatinib and Trametinib for KRAS-mutated Solid Tumor

Who this might be right for
Solid Tumor Cancer
China Medical University Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT07644559
What this trial is testing

VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)G12D Mutated KRAS
Verastem, Inc. 180
Early research (Phase 1)Active Not RecruitingNCT06428500
What this trial is testing

QTX3046 in Patients With KRAS G12D Mutations

Who this might be right for
Advanced Solid Tumor
Quanta Therapeutics 240
Early research (Phase 1)Ended earlyNCT06364696
What this trial is testing

Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 60
Early research (Phase 1)Looking for participantsNCT06619587
What this trial is testing

Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Genentech, Inc. 410
Early research (Phase 1)Not Yet RecruitingNCT07624214
What this trial is testing

Study of LT-010391 in Participants With KRAS G12D-Mutant Solid Tumors

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma (PDAC)+1 more
Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. 198
Testing effectiveness (Phase 2)Looking for participantsNCT06500676
What this trial is testing

GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations

Who this might be right for
KRAS G12D MutationsAdvanced Solid Tumors
Genfleet Therapeutics (Shanghai) Inc. 407
Testing effectiveness (Phase 2)Looking for participantsNCT07640295
What this trial is testing

Study of JAB-23E73 in Combination With Chemotherapy in Participants With Metastatic PDAC Harboring KRAS Gene Alterations

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Jacobio Pharmaceuticals Co., Ltd. 80
Early research (Phase 1)Looking for participantsNCT06403735
What this trial is testing

A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors

Who this might be right for
Non-small Cell Lung CancerColorectal CancerPancreatic Cancer+1 more
Qilu Pharmaceutical Co., Ltd. 250
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