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Results for “KRAS G12V”

34 trials

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Showing 20 of 34 results

Not applicableTemporarily Not AvailableNCT05389514
What this trial is testing

Intermediate-size IND for Treatment of KRAS G12V-mutant Tumors

Who this might be right for
KRAS G12V Mutant Advanced Epithelial Cancers
Providence Health & Services
Early research (Phase 1)Active Not RecruitingNCT06767046
What this trial is testing

KRAS-Specific Autologous TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors

Who this might be right for
ColorectalPancreaticNon-small Cell Lung Cancer (NSCLC)
Corregene Biotechnology Co., Ltd 8
Early research (Phase 1)Not Yet RecruitingNCT07650357
What this trial is testing

CLSP 5282 in HLA-A*03:01 Positive Adult Patients With Solid Tumors (SENTINEL-101)

Who this might be right for
Advanced Solid TumorNon Small Cell Lung CancerPancreatic Carcinoma+1 more
Clasp Therapeutics, Inc. 140
Early research (Phase 1)Looking for participantsNCT06917079
What this trial is testing

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Who this might be right for
Non-Small Cell Lung CancerNSCLCPDAC - Pancreatic Ductal Adenocarcinoma+11 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 665
Testing effectiveness (Phase 2)Looking for participantsNCT04146298
What this trial is testing

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer

Who this might be right for
Pancreatic CancerPancreatic NeoplasmsPancreatic Ductal Adenocarcinoma+1 more
Changhai Hospital 30
Testing effectiveness (Phase 2)WithdrawnNCT06690281
What this trial is testing

A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies

Who this might be right for
Gastrointestinal CarcinomaPancreatic CancerHepatocellular Cancer+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT06105021
What this trial is testing

Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon-Small Cell Lung CancerColorectal Cancer+2 more
Affini-T Therapeutics, Inc. 100
Testing effectiveness (Phase 2)Looking for participantsNCT07629960
What this trial is testing

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more
Blueprint Medicines Corporation 265
Early research (Phase 1)Looking for participantsNCT07094204
What this trial is testing

Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Who this might be right for
Solid TumorNon-Small-Cell Lung CancerPancreatic Ductal Adenocarcinoma+1 more
Astellas Pharma Inc 364
Early research (Phase 1)Looking for participantsNCT06898385
What this trial is testing

A Phase I Clinical Study of IX001 TCR-T Injection in the Treatment of Advanced Pancreatic Cancer Patients With KRAS G12V Mutation

Who this might be right for
Pancreatic Cancer
Sun Yat-sen University 9
Early research (Phase 1)UnknownNCT05933668
What this trial is testing

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Peking University 11
Early research (Phase 1)Not Yet RecruitingNCT06545201
What this trial is testing

RE001 T Cell Injection for the Treatment of KRAS G12V Mutated Solid Tumors

Who this might be right for
KRAS G12VT Cell Therapy
Henan Cancer Hospital 30
Early research (Phase 1)Looking for participantsNCT06962254
What this trial is testing

Imatinib and Trametinib for KRAS-mutated Solid Tumor

Who this might be right for
Solid Tumor Cancer
China Medical University Hospital 10
Early research (Phase 1)Active Not RecruitingNCT07826585
What this trial is testing

Treatment of Patients With Advanced Solid Tumors Using CRTKVA11-03 TCR-T Cell Injection

Who this might be right for
Advanced Solid Tumors
Corregene Biotechnology Co., Ltd 6
Testing effectiveness (Phase 2)Looking for participantsNCT07640295
What this trial is testing

Study of JAB-23E73 in Combination With Chemotherapy in Participants With Metastatic PDAC Harboring KRAS Gene Alterations

Who this might be right for
Metastatic Pancreatic Ductal Adenocarcinoma
Jacobio Pharmaceuticals Co., Ltd. 80
Early research (Phase 1)Looking for participantsNCT07349537
What this trial is testing

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Adenocarcinoma+7 more
Revolution Medicines, Inc. 574
Early research (Phase 1)Active Not RecruitingNCT05631899
What this trial is testing

CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumor, AdultEphA2 OverexpressionKRAS G12V+2 more
Chinese PLA General Hospital 9
Not applicableNo Longer AvailableNCT07083479
What this trial is testing

Expanded Access Protocol of ELI-002-102 in Subjects With KRAS/NRAS Mutated Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal AdenocarcinomaKRAS G12DKRAS G12V+12 more
Elicio Therapeutics
Early research (Phase 1)Active Not RecruitingNCT06447662
What this trial is testing

Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Who this might be right for
Carcinoma, Pancreatic DuctalColorectal NeoplasmsCarcinoma, Non-Small-Cell Lung
Pfizer 64
Testing effectiveness (Phase 2)Looking for participantsNCT05786924
What this trial is testing

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Who this might be right for
Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more
Institut de Recherches Internationales Servier 554
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