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Results for “KRAS Mutant Metastatic Colorectal Cancer”

34 trials

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Showing 20 of 34 results

Early research (Phase 1)Ended earlyNCT04916236
What this trial is testing

Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers

Who this might be right for
Pancreatic CancerColorectal CancerNon-small Cell Lung Cancer+1 more
The Netherlands Cancer Institute 24
Early research (Phase 1)Study completedNCT01274624
What this trial is testing

Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer

Who this might be right for
KRAS Mutant Metastatic Colorectal Cancer
Oncolytics Biotech 36
Early research (Phase 1)Looking for participantsNCT06917079
What this trial is testing

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Who this might be right for
Non-Small Cell Lung CancerNSCLCPDAC - Pancreatic Ductal Adenocarcinoma+11 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 387
Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Early research (Phase 1)Study completedNCT03415126
What this trial is testing

ASN007 in Patients With Advanced Solid Tumors

Who this might be right for
CancerMalignancyNeoplasia+16 more
Asana BioSciences 49
Large-scale testing (Phase 3)Looking for participantsNCT06997497
What this trial is testing

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Who this might be right for
Colon AdenocarcinomaRectal Adenocarcinoma
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT01719380
What this trial is testing

Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Pfizer 156
Early research (Phase 1)Looking for participantsNCT06607185
What this trial is testing

The Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon-small Cell Lung CancerColorectal Cancer+2 more
Eli Lilly and Company 750
Early research (Phase 1)Study completedNCT03597581
What this trial is testing

RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Who this might be right for
Gastrointestinal CancerGastrointestinal NeoplasmsColorectal Cancer+7 more
Inspirna, Inc. 89
Testing effectiveness (Phase 2)Ended earlyNCT01479465
What this trial is testing

Efficacy and Safety of Simtuzumab (SIM) With FOLFIRI as Second Line Treatment in Colorectal Adenocarcinoma

Who this might be right for
Colorectal Cancer
Gilead Sciences 266
Testing effectiveness (Phase 2)Study completedNCT02230553
What this trial is testing

Lapatinib Plus Trametinib in KRAS Mutant NSCLC

Who this might be right for
Colorectal Cancer
The Netherlands Cancer Institute 35
Testing effectiveness (Phase 2)Study completedNCT00856375
What this trial is testing

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Who this might be right for
Colorectal Cancer
Nektar Therapeutics 83
Early research (Phase 1)Looking for participantsNCT06625775
What this trial is testing

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultMetastatic Breast CancerAdvanced Breast Cancer+8 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 392
Testing effectiveness (Phase 2)Study completedNCT01326000
What this trial is testing

RO5083945 in Combination With FOLFIRI Versus FOLFIRI Plus Cetuximab or FOLFIRI Alone as Second Line Treatment in Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hoffmann-La Roche 169
Testing effectiveness (Phase 2)Study completedNCT00813605
What this trial is testing

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Who this might be right for
Metastatic Colorectal Cancer
NantCell, Inc. 155
Early research (Phase 1)Ended earlyNCT02703571
What this trial is testing

Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors

Who this might be right for
Solid Tumors for Phase IbPancreatic Cancer for Phase IIColorectal Cancer for Phase II
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)Ended earlyNCT01032291
What this trial is testing

Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Who this might be right for
Colorectal Cancer
Celgene Corporation 51
Testing effectiveness (Phase 2)Study completedNCT02039336
What this trial is testing

Dacomitinib Plus PD-0325901 in Advanced KRAS Mutant NSCLC

Who this might be right for
Colorectal Cancer
The Netherlands Cancer Institute 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT05983367
What this trial is testing

Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Colon Cancer
Inspirna, Inc. 70
Early research (Phase 1)Looking for participantsNCT06040541
What this trial is testing

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma (PDAC)+1 more
Revolution Medicines, Inc. 604
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