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Results for “KRAS Mutant Metastatic Colorectal Cancer”

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Showing 17 of 0 results

Testing effectiveness (Phase 2)Study completedNCT01719380
What this trial is testing

Study of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Pfizer 156
Testing effectiveness (Phase 2)Looking for participantsNCT07629960
What this trial is testing

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more
Blueprint Medicines Corporation 265
Early research (Phase 1)Active Not RecruitingNCT06607185
What this trial is testing

The Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaNon-small Cell Lung CancerColorectal Cancer+2 more
Eli Lilly and Company 750
Early research (Phase 1)Looking for participantsNCT06411691
What this trial is testing

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Who this might be right for
Colorectal CancerPancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 54
Testing effectiveness (Phase 2)Study completedNCT00856375
What this trial is testing

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Who this might be right for
Colorectal Cancer
Nektar Therapeutics 83
Testing effectiveness (Phase 2)Study completedNCT02230553
What this trial is testing

Lapatinib Plus Trametinib in KRAS Mutant NSCLC

Who this might be right for
Colorectal Cancer
The Netherlands Cancer Institute 35
Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Early research (Phase 1)Active Not RecruitingNCT05462717
What this trial is testing

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma+1 more
Revolution Medicines, Inc. 222
Testing effectiveness (Phase 2)Ended earlyNCT01032291
What this trial is testing

Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Who this might be right for
Colorectal Cancer
Celgene Corporation 51
Large-scale testing (Phase 3)Looking for participantsNCT06997497
What this trial is testing

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Who this might be right for
Colon AdenocarcinomaRectal Adenocarcinoma
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT00813605
What this trial is testing

QUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal Carcinoma

Who this might be right for
Metastatic Colorectal Cancer
NantCell, Inc. 155
Early research (Phase 1)Study completedNCT01274624
What this trial is testing

Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal Cancer

Who this might be right for
KRAS Mutant Metastatic Colorectal Cancer
Oncolytics Biotech 36
Early research (Phase 1)Ended earlyNCT02703571
What this trial is testing

Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors

Who this might be right for
Solid Tumors for Phase IbPancreatic Cancer for Phase IIColorectal Cancer for Phase II
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)Ended earlyNCT05983367
What this trial is testing

Investigate Ompenaclid Combined With FOLFIRI Plus Bevacizumab in Advanced/Metastatic Colorectal Cancer

Who this might be right for
Colorectal CancerMetastatic Colon Cancer
Inspirna, Inc. 76
Early research (Phase 1)Ended earlyNCT04916236
What this trial is testing

Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers

Who this might be right for
Pancreatic CancerColorectal CancerNon-small Cell Lung Cancer+1 more
The Netherlands Cancer Institute 24
Early research (Phase 1)Looking for participantsNCT06336902
What this trial is testing

Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal AdenocarcinomaStage IV Colorectal Cancer AJCC v8
University of Southern California 15
Testing effectiveness (Phase 2)Study completedNCT03981614
What this trial is testing

Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer

Who this might be right for
Metastatic Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8Stage IVA Colorectal Cancer AJCC v8+3 more
Academic and Community Cancer Research United 102