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Results for “KRAS Mutated Colorectal Cancer”

109 trials

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Showing 20 of 109 results

Early research (Phase 1)Study completedNCT04330664
What this trial is testing

Adagrasib in Combination With TNO155 in Patients With Cancer (KRYSTAL 2)

Who this might be right for
Advanced CancerMetastatic CancerMalignant Neoplastic Disease
Mirati Therapeutics Inc. 86
Testing effectiveness (Phase 2)Study completedNCT00827684
What this trial is testing

Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

Who this might be right for
Metastatic Colorectal Cancer
Vejle Hospital 50
Early research (Phase 1)Ended earlyNCT04916236
What this trial is testing

Combination Therapy of RMC-4630 and LY3214996 in Metastatic KRAS Mutant Cancers

Who this might be right for
Pancreatic CancerColorectal CancerNon-small Cell Lung Cancer+1 more
The Netherlands Cancer Institute 24
Testing effectiveness (Phase 2)Study completedNCT01108107
What this trial is testing

Neoadjuvant Treatment of Colon Cancer

Who this might be right for
Colon Cancer
Vejle Hospital 76
Testing effectiveness (Phase 2)Ended earlyNCT01186705
What this trial is testing

Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer

Who this might be right for
Colon CancerRectal Cancer
Memorial Sloan Kettering Cancer Center 1
Large-scale testing (Phase 3)Study completedNCT02394795
What this trial is testing

Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC

Who this might be right for
Colorectal Cancer
Takeda 823
Testing effectiveness (Phase 2)Ended earlyNCT04165031
What this trial is testing

LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Cancer
Eli Lilly and Company 5
Not applicableStudy completedNCT03750175
What this trial is testing

OPTImal PALliative Anti-epidermal Growth Factor Receptor Treatment in Metastatic Colorectal Cancer -

Who this might be right for
Colorectal Cancer MetastaticCirculating Tumor DNAKRAS Gene Mutation+3 more
Karen-Lise Garm Spindler 49
Early research (Phase 1)Looking for participantsNCT06447662
What this trial is testing

Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Who this might be right for
Carcinoma, Pancreatic DuctalColorectal NeoplasmsCarcinoma, Non-Small-Cell Lung
Pfizer 330
Early research (Phase 1)Ended earlyNCT06270082
What this trial is testing

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

Who this might be right for
Solid Tumor, AdultColorectal CancerPancreatic Cancer+7 more
Ikena Oncology 75
Early research (Phase 1)Ended earlyNCT04627142
What this trial is testing

Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Boehringer Ingelheim 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05194995
What this trial is testing

JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced Colorectal CancerSmall Intestinal CancerAppendiceal Cancer
Allist Pharmaceuticals, Inc. 48
Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
Not applicableStudy completedNCT03698253
What this trial is testing

Metastatic Colorectal Cancer Treated With Regorafenib and FOLFIRI

Who this might be right for
Colorectal Cancer
Kaohsiung Medical University Chung-Ho Memorial Hospital 41
Testing effectiveness (Phase 2)Active Not RecruitingNCT05726864
What this trial is testing

ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid Tumors

Who this might be right for
Pancreatic Ductal AdenocarcinomaColorectal CancerKRAS G12D+11 more
Elicio Therapeutics 158
Early research (Phase 1)Looking for participantsNCT07300150
What this trial is testing

PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

Who this might be right for
Colorectal CancerPancreatic CancerNon-Small Cell Lung Cancer+1 more
PAQ Therapeutics, Inc. 195
Early research (Phase 1)UnknownNCT06078800
What this trial is testing

YL-17231 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Shanghai YingLi Pharmaceutical Co. Ltd. 80
Early research (Phase 1)Study completedNCT02906059
What this trial is testing

Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
NYU Langone Health 7
Early research (Phase 1)Ended earlyNCT05737706
What this trial is testing

Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

Who this might be right for
Solid TumorAdvanced Solid TumorNon-small Cell Lung Cancer+2 more
Mirati Therapeutics Inc. 63
Not applicableAvailableNCT04566393
What this trial is testing

Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies

Who this might be right for
Pancreatic CancerSmall Bowel CancerColorectal Cancer+18 more
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