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Results for “KRAS Mutated Colorectal Cancer”

120 trials

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Showing 20 of 120 results

Not applicableLooking for participantsNCT06645236
What this trial is testing

DHF-20-1839-2: Clinical Performance Study Protocol for Therascreen® KRAS RGQ PCR Kit

Who this might be right for
Metastatic Colorectal Cancer (mCRC)
QIAGEN Gaithersburg, Inc 600
Testing effectiveness (Phase 2)Temporarily pausedNCT05200442
What this trial is testing

VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal AdenocarcinomaColorectal Cancer Metastatic+2 more
University of Chicago 53
Early research (Phase 1)Looking for participantsNCT07594067
What this trial is testing

TCR1188-ABC Cells in KRAS-mutated Cancers

Who this might be right for
CholangiocarcinomaColorectal CancerNon-Small Cell Lung Cancer+1 more
University of Pennsylvania 30
Not applicableStudy completedNCT03698253
What this trial is testing

Metastatic Colorectal Cancer Treated With Regorafenib and FOLFIRI

Who this might be right for
Colorectal Cancer
Kaohsiung Medical University Chung-Ho Memorial Hospital 41
Early research (Phase 1)Looking for participantsNCT06720987
What this trial is testing

Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Who this might be right for
KRAS G12C MutationKRAS G12S MutationSolid Tumor Malignancies+1 more
Kumquat Biosciences Inc. 140
Early research (Phase 1)Ended earlyNCT05497336
What this trial is testing

IBI351 in Combination With Cetuximab in Subjects With KRAS G12C Mutated Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Innovent Biologics (Suzhou) Co. Ltd. 8
Early research (Phase 1)Looking for participantsNCT06179160
What this trial is testing

Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Who this might be right for
Solid Tumors
Incyte Corporation 710
Not applicableLooking for participantsNCT06449989
What this trial is testing

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticBrain Metastases, AdultRas (KRAS or NRAS) Gene Mutation+3 more
Blokhin's Russian Cancer Research Center 30
Early research (Phase 1)Ended earlyNCT06270082
What this trial is testing

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

Who this might be right for
Solid Tumor, AdultColorectal CancerPancreatic Cancer+7 more
Ikena Oncology 75
Large-scale testing (Phase 3)Active Not RecruitingNCT04793958
What this trial is testing

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Who this might be right for
Advanced Colorectal CancerMetastatic Colorectal Cancer
Mirati Therapeutics Inc. 461
Testing effectiveness (Phase 2)Looking for participantsNCT06949982
What this trial is testing

Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes

Who this might be right for
Metastatic Colorectal Cancer (mCRC)Colorectal Neoplasms
Sergey Orlov, MD 60
Early research (Phase 1)Ended earlyNCT04627142
What this trial is testing

Test Different Doses of BI 1701963 in Combination With Irinotecan in People With Advanced Bowel Cancer With Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Mutation

Who this might be right for
Metastatic Colorectal Cancer (CRC)
Boehringer Ingelheim 15
Early research (Phase 1)Active Not RecruitingNCT06447662
What this trial is testing

Learn About the Study Medicine PF-07934040 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Genetic Mutation.

Who this might be right for
Carcinoma, Pancreatic DuctalColorectal NeoplasmsCarcinoma, Non-Small-Cell Lung
Pfizer 64
Testing effectiveness (Phase 2)Study completedNCT01442649
What this trial is testing

Efficacy of Chemotherapy, Associated to Either Cetuximab or Bevacizumab, in KRAS Wild-type Metastatic Colorectal Cancer Patients With Progressive Disease After Receiving First-line Treatment With Bevacizumab

Who this might be right for
Colorectal Cancer
UNICANCER 133
Testing effectiveness (Phase 2)Active Not RecruitingNCT04699188
What this trial is testing

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small-Cell LungCarcinoma, Colorectal+7 more
Novartis Pharmaceuticals 344
Early research (Phase 1)Study completedNCT02906059
What this trial is testing

Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
NYU Langone Health 7
Testing effectiveness (Phase 2)Study completedNCT03829410
What this trial is testing

Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS Mutation

Who this might be right for
Metastatic Colorectal CancerKRAS Gene Mutation
Cardiff Oncology 68
Testing effectiveness (Phase 2)Ended earlyNCT04165031
What this trial is testing

LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Cancer
Eli Lilly and Company 5
Testing effectiveness (Phase 2)Study completedNCT05593328
What this trial is testing

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

Who this might be right for
Colorectal CancerMetastatic Colorectal Cancer
Cardiff Oncology 23
Not applicableStudy completedNCT02827565
What this trial is testing

Technical Optimization of Detection of KRAS, BRAF and NRAS Mutations on Tumor DNA Circulating in Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Institut de Cancérologie de Lorraine 30
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