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Results for “KRAS NP_004976.2:p.G12D”

62 trials

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Showing 20 of 62 results

Large-scale testing (Phase 3)Looking for participantsNCT07409272
What this trial is testing

Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Who this might be right for
Pancreatic CancerMetastatic Pancreatic CancerMetastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 614
Early research (Phase 1)Looking for participantsNCT06179160
What this trial is testing

Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Who this might be right for
Solid Tumors
Incyte Corporation 710
Testing effectiveness (Phase 2)Looking for participantsNCT06667544
What this trial is testing

RNK08954 in Subjects With Advanced Solid Tumors With KRAS ((Kirsten Rat Sarcoma) G12D Mutation

Who this might be right for
KRAS G12D Mutation
Ranok Therapeutics (Hangzhou) Co., Ltd. 152
Early research (Phase 1)Looking for participantsNCT06227377
What this trial is testing

QTX3034 in Patients With KRAS G12D Mutation

Who this might be right for
Solid Tumors
Quanta Therapeutics 250
Early research (Phase 1)Active Not RecruitingNCT06428500
What this trial is testing

QTX3046 in Patients With KRAS G12D Mutations

Who this might be right for
Advanced Solid Tumor
Quanta Therapeutics 240
Early research (Phase 1)Looking for participantsNCT07134998
What this trial is testing

Phase I Study of HRS-6093 in Participants With Advanced Solid Tumors Harboring KRAS G12D Mutations

Who this might be right for
Advanced KRAS G12D Mutant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd. 153
Testing effectiveness (Phase 2)Looking for participantsNCT07438106
What this trial is testing

A Phase II Study of HRS-4642 Combined With AG (Nab-paclitaxel and Gemcitabine) as Conversion Therapy for Locally Advanced Pancreatic Cancer

Who this might be right for
Locally Advanced Pancreatic Cancer With KRAS G12D Mutation
The First Affiliated Hospital with Nanjing Medical University 30
Early research (Phase 1)Looking for participantsNCT06619587
What this trial is testing

Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Genentech, Inc. 410
Testing effectiveness (Phase 2)Looking for participantsNCT06385925
What this trial is testing

TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Who this might be right for
Malignant Neoplasm
Tyligand Pharmaceuticals (Suzhou) Limited 440
Testing effectiveness (Phase 2)Looking for participantsNCT06620848
What this trial is testing

HRS-4642 Monotherapy or in Combination With Adebrelimab in the Treatment of Advanced Biliary Tract Tumors.

Who this might be right for
Biliary Tract Cancer
Shanghai Zhongshan Hospital 49
Testing effectiveness (Phase 2)Looking for participantsNCT06500676
What this trial is testing

GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations

Who this might be right for
KRAS G12D MutationsAdvanced Solid Tumors
Genfleet Therapeutics (Shanghai) Inc. 407
Testing effectiveness (Phase 2)Looking for participantsNCT07259590
What this trial is testing

GFH375 Combined With Cetuximab or Chemotherapy in Participants With Solid Tumors Harboring KRAS G12D Mutation

Who this might be right for
Advanced Solid Tumors CancerPDACCRC (Colorectal Cancer)
Genfleet Therapeutics (Shanghai) Inc. 126
Testing effectiveness (Phase 2)Looking for participantsNCT03608631
What this trial is testing

IExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

Who this might be right for
KRAS NP_004976.2:p.G12DMetastatic Pancreatic AdenocarcinomaPancreatic Ductal Adenocarcinoma+1 more
M.D. Anderson Cancer Center 28
Early research (Phase 1)Active Not RecruitingNCT05631899
What this trial is testing

CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors

Who this might be right for
Solid Tumor, AdultEphA2 OverexpressionKRAS G12V+2 more
Chinese PLA General Hospital 9
Early research (Phase 1)Looking for participantsNCT05382559
What this trial is testing

ASP3082 in Adults With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 681
Testing effectiveness (Phase 2)Looking for participantsNCT06770452
What this trial is testing

HRS-4642 With Nimotuzumab and Chemotherapy for First-line Treatment of Advanced Pancreatic Cancer Patients

Who this might be right for
Metastatic Pancreatic Carcinoma
Zhejiang University 133
Testing effectiveness (Phase 2)Looking for participantsNCT05786924
What this trial is testing

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

Who this might be right for
Non-small Cell Lung CancerHistiocytic NeoplasmHistiocytosis+29 more
Institut de Recherches Internationales Servier 554
Testing effectiveness (Phase 2)Active Not RecruitingNCT06385678
What this trial is testing

HRS-4642 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

Who this might be right for
Advanced KRAS G12D Mutant Solid Tumors
Jiangsu HengRui Medicine Co., Ltd. 47
Early research (Phase 1)Active Not RecruitingNCT06364696
What this trial is testing

Find a Suitable Dose of ASP4396 in Adults With Solid Tumors

Who this might be right for
Solid Tumor
Astellas Pharma Inc 175
Early research (Phase 1)Looking for participantsNCT07094204
What this trial is testing

Find a Suitable Dose of ASP5834 in Adults With Solid Tumors

Who this might be right for
Solid TumorNon-Small-Cell Lung CancerPancreatic Ductal Adenocarcinoma+1 more
Astellas Pharma Inc 364
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