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Results for “KRAS-mutant Non-small Cell Lung Cancer (NSCLC)”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05009329
What this trial is testing

JAB-21822 in Adult Patients With Advanced Solid Tumors Harboring KRAS p.G12C Mutation in China

Who this might be right for
NSCLCSolid Tumor
Allist Pharmaceuticals, Inc. 315
Large-scale testing (Phase 3)Not Yet RecruitingNCT07242274
What this trial is testing

Phase 3 Trial of JMKX001899 Versus Docetaxel in Previously Treated Advanced or Metastatic KRAS G12C-Mutant NSCLC

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Jemincare 472
Large-scale testing (Phase 3)Active Not RecruitingNCT05132075
What this trial is testing

Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)Looking for participantsNCT07148128
What this trial is testing

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Who this might be right for
Advanced or Metastatic KRAS-mutant Tumor in Pancreatic AdenocarcinomaAdvanced or Metastatic KRAS-mutant Tumor in Colorectal CancerAdvanced or Metastatic KRAS-mutant Tumor in Non Small Cell Lung Cancer+2 more
Auricula Biosciences Inc.
Early research (Phase 1)Looking for participantsNCT06625775
What this trial is testing

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumor, AdultMetastatic Breast CancerAdvanced Breast Cancer+8 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 392
Early research (Phase 1)Ended earlyNCT05374538
What this trial is testing

VIC-1911 Monotherapy in Combination With Sotorasib for the Treatment of KRAS G12C-Mutant Non-Small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Vitrac Therapeutics, LLC 3
Testing effectiveness (Phase 2)Looking for participantsNCT06582771
What this trial is testing

Sotorasib in People With Non-Small Cell Lung Cancer

Who this might be right for
Non Small Lung Cancer
Memorial Sloan Kettering Cancer Center 39
Testing effectiveness (Phase 2)Study completedNCT03704688
What this trial is testing

Trial of Trametinib and Ponatinib in Patients With KRAS Mutant Advanced Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung CancerKRAS Gene Mutation
Memorial Sloan Kettering Cancer Center 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT05358249
What this trial is testing

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Who this might be right for
KRAS G12C Mutant Solid TumorsCarcinoma, Non-Small Cell LungCarcinoma, Non-Small-Cell Lung+8 more
Novartis Pharmaceuticals 74
Early research (Phase 1)Looking for participantsNCT06917079
What this trial is testing

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

Who this might be right for
Non-Small Cell Lung CancerNSCLCPDAC - Pancreatic Ductal Adenocarcinoma+11 more
TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics) 665
Testing effectiveness (Phase 2)WithdrawnNCT05180422
What this trial is testing

A Phase I/II Study of AMG 510 in Combination With MVASI in Patients With Advanced, Unresectable or Metastatic KRAS G12C Mutant NSCLC With Asymptomatic Brain Metastasis

Who this might be right for
Non Small Cell Lung Cancer
Criterium, Inc.
Early research (Phase 1)Active Not RecruitingNCT05462717
What this trial is testing

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma+1 more
Revolution Medicines, Inc. 222
Testing effectiveness (Phase 2)Study completedNCT01362296
What this trial is testing

An Open-label Study of GSK1120212 Compared With Docetaxel in Stage IV KRAS-mutant Non-small Cell Lung Cancer

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT03808558
What this trial is testing

Phase 2 Study of TVB-2640 in KRAS Non-Small Cell Lung Carcinomas

Who this might be right for
KRAS Gene Mutation
David E Gerber 18
Large-scale testing (Phase 3)Looking for participantsNCT07190248
What this trial is testing

A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 675
Testing effectiveness (Phase 2)UnknownNCT02450656
What this trial is testing

Afatinib and Selumetinib in Advanced KRAS Mutant and PIK3CA Wildtype Non-small Cell Lung Cancer

Who this might be right for
Colorectal NeoplasmsGastrointestinal NeoplasmsPancreatic Neoplasms+1 more
The Netherlands Cancer Institute 320
Testing effectiveness (Phase 2)Active Not RecruitingNCT05673187
What this trial is testing

Adagrasib in Patients With KRASG12C-mutant NSCLC Who Are Elderly or Have Poor Performance Status

Who this might be right for
NSCLC Stage IVKRAS P.G12C
ETOP IBCSG Partners Foundation 68
Early research (Phase 1)Looking for participantsNCT05254184
What this trial is testing

KRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 12
Large-scale testing (Phase 3)Looking for participantsNCT07554339
What this trial is testing

A Clinical Trial of Calderasib (MK-1084) and Durvalumab in People With Non-Small Cell Lung Cancer (MK-1084-015/KANDLELIT-015)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 310
Testing effectiveness (Phase 2)Looking for participantsNCT07629960
What this trial is testing

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

Who this might be right for
Advanced Solid TumorNon-Small Cell Lung CancerColorectal Neoplasms+1 more
Blueprint Medicines Corporation 265
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