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Results for “LA HNSCC”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03765918
What this trial is testing

Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689)

Who this might be right for
Head and Neck Neoplasms
Merck Sharp & Dohme LLC 714
Testing effectiveness (Phase 2)Looking for participantsNCT06978829
What this trial is testing

Cetuximab + Tislelizumab + Chemotherapy in the Treatment of Unresectable LA HNSCC

Who this might be right for
LA HNSCC
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 42
Testing effectiveness (Phase 2)UnknownNCT02753140
What this trial is testing

Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy

Who this might be right for
Carcinoma, Squamous Cell of Head and Neck
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 60
Testing effectiveness (Phase 2)Ended earlyNCT01216020
What this trial is testing

Cetuximab Plus Radiotherapy Versus Cisplatin Plus Radiotherapy in Locally Advanced Head and Neck Cancer

Who this might be right for
Head and Neck NeoplasmsLaryngeal NeoplasmsMouth Neoplasms+1 more
Azienda USL 4 Prato 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT05522985
What this trial is testing

Toripalimab-based Neoadjuvant Therapy in LA-HNSCC

Who this might be right for
Head and Neck Squamous Cell CarcinomaNeoadjuvant Chemotherapy
Tianjin Medical University Cancer Institute and Hospital 122
Early research (Phase 1)Study completedNCT02381535
What this trial is testing

Onalespib in Treating Patients With Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck Receiving Radiation Therapy and Cisplatin

Who this might be right for
Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7+9 more
National Cancer Institute (NCI) 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT05366166
What this trial is testing

Pembrolizumab Plus Olaparib in LA-HNSCC

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
UNC Lineberger Comprehensive Cancer Center 45
Large-scale testing (Phase 3)Not Yet RecruitingNCT07371897
What this trial is testing

Toripalimab ± Chemo as Neoadjuvant Therapy in LA-HNSCC: A Phase III Trial

Who this might be right for
Head and Neck Squamous Cell Carcinoma HNSCC
Sun Yat-sen University 154
Large-scale testing (Phase 3)Looking for participantsNCT04892173
What this trial is testing

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

Who this might be right for
Carcinoma, Squamous Cell
Johnson & Johnson Enterprise Innovation Inc. 500
Large-scale testing (Phase 3)Looking for participantsNCT06102395
What this trial is testing

Evaluating the Efficacy and Safety of Pembrolizumab Plus Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCC

Who this might be right for
Head and Neck Squamous Cell CarcinomaNeoadjuvant TherapyPembrolizumab
Beijing Tongren Hospital 272
Testing effectiveness (Phase 2)Looking for participantsNCT06752798
What this trial is testing

Bone Marrow Protective Effect of Trilaciclib in Postoperative CCRT for LA-HNSCC

Who this might be right for
Head and Neck Cancer Squamous Cell Carcinoma
Hunan Cancer Hospital 30
Early research (Phase 1)Study completedNCT02537223
What this trial is testing

Phase I Study of BYL719 in Combination With Cisplatin and Radiotherapy in Patients With Squamous Cell Head and Neck Cancer

Who this might be right for
Squamous Cell Carcinoma of Head and NeckLocoregionally Advanced
University Health Network, Toronto 9
Not applicableNot Yet RecruitingNCT06722495
What this trial is testing

Efficacy and Safety of a Third-Course of Neoadjuvant Immunochemotherapy Combined With SBRT in Locally Advanced Head and Neck Squamous Cell Carcinoma Patients With Stable Disease After Two Treatment Courses: A Single-Arm Exploratory Study

Who this might be right for
SBRTNeoadjuvant ImmunochemotherapyLA HNSCC
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 20
Very early researchNot Yet RecruitingNCT07168785
What this trial is testing

[18F]-AraG PET Imaging in LA HNSCC

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)Locally Advanced Head and Neck Squamous Cell Carcinoma
Indiana University 5
Testing effectiveness (Phase 2)Active Not RecruitingNCT03410615
What this trial is testing

Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Followed by Tremelimumab + Durvalumab in Intermediate-Risk HPV-Positive Oropharyngeal SCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
Canadian Cancer Trials Group 129
Not applicableStudy completedNCT03838601
What this trial is testing

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2

Who this might be right for
Head and Neck Squamous Cell Carcinoma
University Health Network, Toronto 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07310771
What this trial is testing

Sintilimab-Nimotuzumab Induction Followed by Chemoradiation-Nimotuzumab in LA-HNSCC: Single-Arm Phase II

Who this might be right for
Locally Advanced Head and Neck Squamous Cell Carcinoma (LA-SCCHN)
Fujian Cancer Hospital 23
Testing effectiveness (Phase 2)Looking for participantsNCT05414032
What this trial is testing

Molecular Residual Disease Interception in Locoregionally-Advanced High Risk HPV+ and HPV- HNSCC

Who this might be right for
Locoregionally Advanced Head and Neck Squamous Cell Carcinoma (LA-HNSCC)
University Health Network, Toronto 102
Large-scale testing (Phase 3)Active Not RecruitingNCT02999087
What this trial is testing

Randomized Trial of Avelumab-cetuximab-radiotherapy Versus SOCs in LA SCCHN (REACH)

Who this might be right for
HNSCC
Groupe Oncologie Radiotherapie Tete et Cou 707
Testing effectiveness (Phase 2)Study completedNCT05213884
What this trial is testing

The Efficacy of Induction and Adjuvant Camrelizumab Combined With Chemoradiation for LA-HNSCC

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Chongqing University Cancer Hospital 39
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