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Results for “LCH”

86 trials

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Showing 20 of 86 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040
What this trial is testing

Lenalidomide for Adult Histiocyte Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS)
Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Looking for participantsNCT05828069
What this trial is testing

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Who this might be right for
Recurrent Langerhans Cell HistiocytosisRefractory Langerhans Cell Histiocytosis
National Cancer Institute (NCI) 48
Large-scale testing (Phase 3)Looking for participantsNCT04943211
What this trial is testing

Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging

Who this might be right for
Histiocytosis
Anna Raciborska 150
Testing effectiveness (Phase 2)Looking for participantsNCT04079179
What this trial is testing

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Who this might be right for
Langerhan's Cell HistiocytosisJuvenile XanthogranulomaErdheim-Chester Disease+4 more
Carl Allen 90
Testing effectiveness (Phase 2)Looking for participantsNCT06078969
What this trial is testing

Oral Prednisone in Treating LCH of Bone in Childhood and Adolescence

Who this might be right for
Langerhans Cell Histiocytosis of Bone
Shanghai Changzheng Hospital 118
Large-scale testing (Phase 3)Not Yet RecruitingNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+16 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Looking for participantsNCT06582745
What this trial is testing

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Who this might be right for
Langerhans Cell Histiocytosis
Cook Children's Health Care System 75
Early research (Phase 1)Ended earlyNCT00002947
What this trial is testing

Indium In 111 Pentetreotide in Treating Patients With Refractory Cancer

Who this might be right for
Brain and Central Nervous System TumorsChildhood Langerhans Cell HistiocytosisGastrointestinal Carcinoid Tumor+9 more
Yale University 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
Testing effectiveness (Phase 2)Ended earlyNCT00618540
What this trial is testing

Reduced Intensity Hematopoietic Cell Transplantation for Patients With Resistant Langerhans Cell Histiocytosis

Who this might be right for
Histiocytosis, Langerhans-cell
Masonic Cancer Center, University of Minnesota 1
Not applicableStudy completedNCT02608619
What this trial is testing

Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement

Who this might be right for
Erdheim-Chester DiseaseLangerhans Cell HistiocytosisHistiocytic Disorders
Memorial Sloan Kettering Cancer Center 3
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Looking for participantsNCT07187193
What this trial is testing

Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

Who this might be right for
Langerhans Cell Histiocytosis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 50
Not applicableLooking for participantsNCT04665674
What this trial is testing

Adult Pulmonary Langerhans Cell Histiocytosis: a National Registry-based Prospective Cohort Study

Who this might be right for
HistiocytosisHistiocytosis, Langerhans-CellHistiocytosis Pulmonary
Assistance Publique - Hôpitaux de Paris 500
Testing effectiveness (Phase 2)Study completedNCT01273766
What this trial is testing

Deferasirox in Treating Iron Overload Caused By Blood Transfusions in Patients With Hematologic Malignancies

Who this might be right for
Acute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+133 more
Wake Forest University Health Sciences 16
Not applicableUnknownNCT03093727
What this trial is testing

Characterization of Pulmonary Langerhans Cell Histiocytosis

Who this might be right for
Langerhans Cell Histiocytoses
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 20
Large-scale testing (Phase 3)Looking for participantsNCT02670707
What this trial is testing

Vinblastine/Prednisone Versus Single Therapy With Cytarabine for Langerhans Cell Histiocytosis (LCH)

Who this might be right for
Langerhans Cell Histiocytosis
Baylor College of Medicine 124
Testing effectiveness (Phase 2)Study completedNCT03096782
What this trial is testing

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Looking for participantsNCT05997602
What this trial is testing

To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCH

Who this might be right for
Langerhans Cell HistiocytosisLCH
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT02061800
What this trial is testing

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Who this might be right for
Chronic Myeloid Leukemia (CML)Acute Myelogenous Leukemia (AML)Myelodysplastic Syndrome (MDS)+3 more
Diane George 14
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