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Results for “Langerhans Cell Histiocytoses”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT04943211
What this trial is testing

Determination of Molecular Status, the Efficacy and Safety of Fluorodeoxyglucose in PET-CT Imaging

Who this might be right for
Histiocytosis
Anna Raciborska 150
Testing effectiveness (Phase 2)Looking for participantsNCT06582745
What this trial is testing

Targeted Approach to Langerhans Cell Histiocytosis (LCH) Using MEK Inhibitor, Trametinib

Who this might be right for
Langerhans Cell Histiocytosis
Cook Children's Health Care System 75
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Study completedNCT02472054
What this trial is testing

Treatment of Familiar Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)
Assistance Publique - Hôpitaux de Paris 29
Testing effectiveness (Phase 2)UnknownNCT05008666
What this trial is testing

Induction Chemotherapy Sequential Sintilimab Combined With Dual Epigenetic Drugs for ENKTL-HLH

Who this might be right for
Safety and Efficacy
Sun Yat-sen University 37
Testing effectiveness (Phase 2)Looking for participantsNCT07525466
What this trial is testing

Combination of Mitoxantrone Liposome and Etoposide, Dexamethasone, Pegaspargase and Golidocitinib (MEPL-G) in the Treatment of NK/T-cell Lymphoma Associated Hemophagocytic Lymphohistiocytosis (NKTCL-HLH)

Who this might be right for
Extranodal NK T Cell LymphomaHemophagocytic Lymphohistiocytosis (HLH)
Beijing Tongren Hospital 25
Large-scale testing (Phase 3)Looking for participantsNCT05163288
What this trial is testing

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Who this might be right for
Niemann-Pick Disease, Type C
IntraBio Inc 53
Large-scale testing (Phase 3)Ended earlyNCT04958642
What this trial is testing

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Who this might be right for
Niemann-Pick Disease, Type C
Mandos LLC 66
Testing effectiveness (Phase 2)Study completedNCT02912793
What this trial is testing

Safety and Efficacy of Intravenous Trappsol Cyclo (HPBCD) in Niemann-Pick Type C Patients

Who this might be right for
Niemann-Pick Disease, Type C1
Cyclo Therapeutics, Inc. 12
Post-approval studies (Phase 4)Active Not RecruitingNCT03975829
What this trial is testing

Pediatric Long-Term Follow-up and Rollover Study

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+20 more
Novartis Pharmaceuticals 163
Not applicableUnknownNCT06587191
What this trial is testing

Emapalumab Efficacy in Children With Primary Hemophagocytic Lymphohistiocytosis

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 7
Testing effectiveness (Phase 2)UnknownNCT04924647
What this trial is testing

Lenalidomide and Dexamethasone for Rosai-Dorfman Disease

Who this might be right for
Rosai-Dorfman Disease
Peking Union Medical College Hospital 16
Testing effectiveness (Phase 2)Study completedNCT03213678
What this trial is testing

Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+30 more
National Cancer Institute (NCI) 18
Not applicableStudy completedNCT01899950
What this trial is testing

Longitudinal Study of Cognition With Niemann-Pick Disease, Type C

Who this might be right for
Niemann-Pick Disease, Type C
Mayo Clinic 70
Testing effectiveness (Phase 2)Study completedNCT03270020
What this trial is testing

Denosumab for the Treatment of Adult LCH

Who this might be right for
Langerhans Cell Histiocytosis
Hellenic Society for the Study of Bone Metabolism 10
Testing effectiveness (Phase 2)UnknownNCT06244862
What this trial is testing

JAK Inhibitor in Acquired Hemophagocytic synDrome in the Intensive Care Unit

Who this might be right for
Hemophagocytic Syndromes
Assistance Publique - Hôpitaux de Paris 42
Testing effectiveness (Phase 2)Study completedNCT05758922
What this trial is testing

Phase 2 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZ-3102 in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease

Who this might be right for
GM2 GangliosidosisNiemann-Pick Disease, Type C
Azafaros B.V. 13
Testing effectiveness (Phase 2)WithdrawnNCT01796405
What this trial is testing

Clofarabine for Langerhans in Pedi

Who this might be right for
Langerhans Cell Histiocytosis
Dana-Farber Cancer Institute
Not applicableStudy completedNCT05775705
What this trial is testing

L-DEP Regimen Combined With PD-1 Antibody as Induction Therapy for Epstein-Barr Virus-positive LA-HLH

Who this might be right for
PD-1 AntibodyHemophagocytic LymphohistiocytosisEpstein-Barr Virus+1 more
Beijing Friendship Hospital 24
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